History of

Biotechnology
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Shoot the Boot History Of Biote Timeline of Eve X MARKS Are you
chnology nts THE SPOT! Done?
A fun pre-activity a Before taking a peak People and Inventi A fun activity await Finished?
waits you! of the timeline, you m ons can be found in s your presence!
ust first know some k this part!
eywords.
 1st Agenda: Before anything else, it’s
important

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know what we lack in and
what we excel in. In the
1st agenda, we will be
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 Who was named after
the cloned sheep
experiment last 1996?

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 When were
proteins
discovered?

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 When did James
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Crick won their Nobel
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 What is the first
known insecticide?

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 On 1928, the
antibiotic penicillin
was discovered by
whom?

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 2nd Agenda:
History Of Biotechnology
Before taking a peak of the timeline, you must first know some
keywords and the origins of biotechnology.
 Next

History Of Biotechnology:
BIOTECHNOLOGY
The term “Biotechnology” was first used by Karl
Ereky in 1919 in a book called "Biotechnology of
Meat, Fat and Milk Production in an Agricultural
Large-Scale Farm

The term “Biotechnology" indicated the process by

which raw materials could be biologically upgraded
into socially useful products.
 Back Next

History Of Biotechnology:
BIOTECHNOLOGY
In both of these definitions, you see the term living
things. Throughout the module, you will often see the
word organisms used instead of living things.

These things are so small that you can see them only by
viewing them through the microscope. These very small
things are called microorganisms. Biotechnology aims
to make use of living things to improve or benefit
people’s lives.
 Back

History Of Biotechnology:
BIOTECHNOLOGY
Biotechnology is not a new technology as it had been
traditionally used by man since time immemorial without
knowing the scientific principles involved in the process.

Biotechnology as explained above has the newest roots

in the science of molecular biology, genetic engineering,
and microbiology.

Biotechnology has now become a key to boost the

economy and health industries of different nations.
 3rd Agenda:
Timeline of Events
People and Inventions can be found in this part! If you see 2
definitions in a year, try clicking the picture! Navigate by using your
keyboard arrows!
 Timeline: 1590
Zacharias Janssen invents the
microscope.

10,000 C.E- 2000 C.E
Biotechnology was used for the first
time when the Egyptians use yeast
to leaven bread and ferment beer.
10,000 C.E- 2000 C.E
Early domestication of animals and
crops, cheese, wine bread use yeast
and bacteria for fermentation
process. It occurred in Sumeria,
China and Egypt
500 C.E.
Chinese use the first antibiotic:
Moldy soybean curds for treating
boils.
 1675
Antoni van Leeuwenhoek
first observations of protons
and bacteria.

1663 1786 1830

Cell was discovered by Edward Jenner invented the
Smallpox vaccine that in 1980
Proteins are
Robert Hooke. discovered
it declared smallpox to be
eradicated
 1861
Proposal of Louis
Pasteur of Germ theory
of Disease

1833 1838-1839 1859

First enzyme was The proposal of Matthias Charles Darwin writes
discovered and isolated Schleiden and Theodor “Origin of species”
Schwann that all living
things are made up of cell.
 1915
Production of Baker’s yeast
(Saccharomyces cerevisiae)

1911 1919 1928

Thomas Hunt Morgan The word “biotechnology” Alexander Fleming
discovered chromosomes is used in print for the first discovered penicillin
that carry genes time
 1962
Watson and Crick shared
the 1962 Nobel Prize in
medicine or Physiology
with Maurice Wilkins

1944 1953 1958

Oswald Avery, Colin James Waston and Francis DNA made in a test tube for
MacLeod and McCarty Crick describe the DNA as a the first time; Sickle cell
proved DNA carry genetic Double helix. disease occurred due to a
info as the hereditary. change in an amino acid
 1973
Staley Cohen and Henry Boyer develop
ways to cut and splice DNA, opening a
way for Gene cloning; Recombinant
DNA, restriction enzymes were
discovered,

1969 1977 1981

An enzyme is synthesized Genetic engineering is First transgenic animals
in vitro for the first time done for the first time. are produced.

1982
Human insulin gene inserted into
bacterial plasmid. Diabetes was
treated with genetically
engineered insulin instead of pig
insulin.
1986
First anti-cancer drug
produced through biotech:
interferon.
1982 1983
First biotech drug was The polymerase chain
approved by the FDA, a reaction technique (PCR) is
vaccine for Hepatitis. conceived.
 1994
Flavr Savr tomato was approved by
the FDA . The tomato was
genetically engineered to resist
rotting.

1990 1996 1996

Human genome project was The sequencing of baker’s yeast Biotech crops were
funded by the congress; genome is completed; Dolly the introduced into the
Golden rice was developed sheep was cloned by Ian Wilmut market.
to solve nutrient deficiency. and Keith Campbell.
 2003
A far more precise version
of the human genome –
one that is 99.999%
accurate is published

1998 2002 2003

Human embryonic stem cell Draft version of the Severe acute respiratory
lines are established. complete map of the syndrome (SARS) is
human genome is sequenced three weeks after
published. its discovery.
 2004
Avastin, a recombinant monoclonal
antibody, is the first targeted biological
therapy to receive FDA Approval

2004 2006 2007

The first kitten is cloned FDA approval in vaccine Scientist discovered how
(CopyCat, CC). against the human papilloma to use human skin cells to
virus create embryonic stem
cells.
 2011
A trachea derived from
stem cells is transplanted
into a human recipient.

2008 2009 2010

Japanese scientists create US Congress fees up Researcher at the J. Craig
the first DNA molecule made federal funding for broader Venter Institute create the
almost entirely artificial parts. embryonic stem cell first synthetic cell
research.
 2011
European scientists begin clinical
trials for an anti HIV biotech medicine
produced using genetically modified
tobacco.

2011 2012 2013

Advance 3D printing The FDA Issues draft guidelines The U.S Supreme Court
technology lead to "skin for biosimilar drugs; FDA rules that naturally
printing " approval for the Flucelvax, the occuring genes cannot be
first cell-culture vaccine in the patented.
U.S
X MARKS
THE SPOT!

START
MECHANICS
DONE?
 Who coined the word
“biotechnology?”

Alexander Fleming Louis Pasteur Karl Ereky

 What did the Chinese use as
the first antibiotic?

Moldy Soybean Fermented Kimchi Red Yeast Rice

 In what year did Edward
Jenner invent the smallpox
vaccine?
1786 1998 1803
In 1996 the genetic code of DNA
was cracked. True or False?
No Answer False True
The Japanese scientist created the first DNA
molecule made almost entirely out of
artificial parts in the year?

2017 2013 2008

 What is the name of the first
cloned pet?
Scooby Doo CopyCat Mr. Bubbles
Who proposed the “Germ Theory
of Diseases?”
Kim Jiwoo Louis Pasteur Aristotle
 It was 1861 when Charles Darwin writes
“Origin of Species”. True or False? When
was DNA is made in a test tube for the first
time?
True, 1958 False, 1958 No Answer, 1991
GOOD JOB
HUNTER!

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