CARE OF THE

CLIENTS
WITH IMMUNOLOGIC
(DISORDERS)
CHAPTER 21
“Today is your opportunity
to build the tomorrow -Ken Poirot
you want”
 Introduction

● The immune system is the body’s protection against invading foreign bodies. An
immune system that is impaired is unable to protect the body from a wide variety
of diseases ranging from severe infection, allergies, to immune disease.
● This chapter aims to assist you, nursing student to develop the essential knowledge,
skill and attitudes to provide quality, compassionate and humane care among client
with immunologic disorders.
 Learning outcome
At the end of this Chapter, the learner will be able to:
● Assess the client for clinical manifestation of immunologic disorders.
● Discuss the risk factor, basic pathophysiology and clinical manifestations
associated with common immunologic disorders.
● Develop plans of care for the prevention of injury, collaborative management
and rehabilitation of client with immunologic disorders.
● Implement interventions that optimize the quality of life for clients with
immunologic disorders.
● Evaluate effectiveness of management of client with immunologic disorders
based on outcome criteria developed in the planning phase of care.
Immunologic
Disorders
 Immunologic Disorders

● Immunodeficiencies - deficiencies in the

proper expression of the immune response
system.
 Immunologic Disorders
 Two types:
a. Primary Immunodeficiencies
● Deficiencies resulting from proper development of the
immunosuppressive cells and tissues.
● Mainly genetic disorders seen in children.
b. Secondary Immunodeficiencies
● Any condition that can interfere with the normal growth or
expression of the immune response system.
 Primary Immunodeficiencies

1. T-cell deficiency: Di-George’s Syndrome

(Thymic Hypoplasia)
● Absence of thymus in the neonate.
● Hypocalcemia and tetany - secondary to
hypoparathyroidism.
 Primary Immunodeficiencies

2. B-cell Deficiency: (Bruton’s

agammaglobulinemia)
○ Infantile sex - inked agammaglobulinemia
wherein all immunoglobulins are depressed
○ Found only in boys.
 Primary Immunodeficiencies

3. Common Variable Immunodeficiency (CVID)

○ Becomes evident when the person becomes
an adult, the deficiencies are primally IgA and
IgM.
 Primary Immunodeficiencies

4. Severe Combined Immunodeficiency

Disease
○ Complete absence of both cellular and
humoral immunity
 Primary Immunodeficiencies

5. Phagocytic Defect - chronic Granulomatous

Disease (CGD)
○ Sex - linked recessive disease in males
producing lack of destruction of phagocytized
organisms and particles.
THE END