Professional Documents
Culture Documents
DISEASE NURSING
Agents
1. Virus
3. Rickettsia
a. Unable to grow on artificial media
b. All rickettsial diseases are transmitted by arthropods (ticks,
flea, mites, lice )
c. Require living cell for growth and multiplication
4. Spirochete
a. Spiral-shape bacteria
b. Move in an spiral, helical, or inch-worm manner (leptospira)
7. Protozoa
•Single-celled organism
•Composed of two stages;
a) Throphozoite is the motile, feeding, and dividing stage of life
cycle
b) Cyst- the dormant, survival stage
CHAIN OF INFECTION
5. Portals of entry
6. Susceptible host
Factors in consider in the host’s resistance;
1. Natural or inherent
Vaccines:
1. Preventive aspect
· Health education
· Immunization
Levels of prevention
a. Primary – considered as the true prevention
- precedes a disease or dysfunction
- applied to clients who are physically and
emotionally healthy
b. Secondary – focuses on individuals who are
experiencing health problems
- protecting those who are risk for
developing complications
- geared toward early diagnosis
and treatment
c. Tertiary – nursing management is directed toward pre-
vention of complication, deterioration and disability
2. Control system
· Isolation
· Quarantine
· Disinfection
♠ Concurrent
♠ Terminal
· Disinfestation
· Fumigation
· Use of PPE
· Universal/Standard precaution
3. Curative
· Medical management
· Nursing management
4. Rehabilitative
· Activity
· Nutrition
DISEASES AFFECTING THE
CENTRAL
NERVOUS SYSTEM
Tetanus
(Lockjaw)
Pathogenesis:
- Clostridium tetani enters the body, produce local infection and
tissue necrosis
- While reproducing, release toxin, absorbed by the bloodstream
and the lymphatics, spread to the CNS to the anterior horn cells
of the spinal cord, thus, stimulate contraction of the muscles
supplied by the neurons to which toxin difuses.
Clinical Manifestations:
A. Neonate
ü Feeding and sucking difficulty
ü Excessive crying
ü Spasm and cyanosis (spasm provoked by stimuli)
ü Exhaustion
ü D E A T H
B. Older children and adults:
Complications:
1. Respiratory
a) Hypostatic pneumonia
b) Hypoxia due to laryngospasm
c) Atelectasis
d) Pneumothorax
2. Due to trauma
a) Laceration of the tongue and bucal mucosa
b) Intramuscular hemtoma
c ) Fracture of the ribs and the spine due to prolong
opisthotonos
3. Septicemia
b) Gram staining
c) Smear and blood culture
c) Urine culture
Types of Meningitis:
1. Aseptic meningitis
Complications:
Nursing Management:
Ø Assess neurologic condition of patient
Ø Observe level of consciousness
Ø Check for signs of ICP
ü Plucking at bedcovers
ü Projectile vomiting
ü Seizures
ü Change in motor functions and vital signs
Ø Maintain adequate fluid intake to avoid dehydration but
avoid fluid overload to prevent cerebral edema
Ø Correct positioning to prevent deformities, pressure sores and
respiratory complications
Ø Maintain adequate nutrition and elimination
Ø Isolation
Ø Provide reassurance to patient and the family
Decortication
Meningococcemia
Nursing Management:
Ø Isolation
Ø Strict aseptic technique
Ø Emotional support
Prevention:
Ø Classifications:
d. Japanese Encephalitis
Clinical Manifestations:
Ø A specific, viral infection communicated to man by an infected
animal
Ø Recommended first aid is to wash the wound with soap and water
for about 3 minutes and apply tincture of iodine
Ø Incubation period is 1 week – 7 months in dogs; and 10
2. Excitement/Neurological phase
Diagnostic Tests:
1. Virus isolation from the patient’s saliva and throat
2. Fluorescent rabies-antibody (FRA) – provides the most definitive
diagnosis
3. Presence of negri bodies in the dog’s brain
Treatment Modalities:
1. Thoroughly wash wound with soap and water
2. Immunization/vaccination
3 ATS/TAT infiltrated around the wound or IM ANST
4. Anti-rabies vaccine, both passive and active
Schedule of Vaccination (Adopted from SLH)
A. Passive
1. ERIG - P
2. ERIG – B
3. HRIG
B. Active
1) Standard Regimen
PVRV (Verorab) PCEC (Rabiphur)
Prevention:
1. Vaccination of all dogs
2. Enforcement of the regulation regarding stray dogs
3. Public education in avoiding or reporting all animals that appear
weak.
POLIOMYELITIS
(Heine-medin Dse; Infantile paralysis)
· Caused by a filterable virus., Picorna virus, or Legio Debilitan
· Incubation period is 7 – 21 days
· Pd of communicabiolty – 3 days to 3 months
· Mode of transmission:
ü Direct contamination with oropharyngeal secretions and feces
ü Through carriers
ü Indirectly, through contaminated articles, water and food
· Predisposing Factors:
ü Age : 80% less than 10 years old
ü Sex : More in male than in female
ü Environment and hygienic condition
ü Excessive work, strain, overexertion
Types:
A. Abortive ( accounts 4 – 8 % )
ü Does not invade the CNS
ü Headache and sore throat
ü Moderate grade fever
ü Occasional vomiting
ü Low lumbar pain
ü Patient usually recover within 72 hours
B. Pre-paralytic
C.3. Bulbospinal
o Involvement of the neurons both the brainstem and the
spinal cord
Pathogenesis:
1. Intestinal phase
· Organism enters the mouth, multiply in the oropharynx,
proceed to the intestines where they lodge and multiply
2. Viremic phase
· Organisms are spread to the regional lymph nodes and the
bloodstream
3. Neural phase
· Organisms migrate to the CNS
Complications:
1. Respiratory failure
2. Circulatory collapse
3. Electrolyte imbalance
4. Urinary paralysis
5. Abdominal distension
Diagnostic Procedures
· Throat swab
· Stool culture
· CSF analysis
Nursing Management:
· Enteric isolation
· Observe and assess for neurologic changes
· Watch for fecal impaction
· Carry out strict medical asepsis
· Proper disposal of excreta and vomitus
· Provide emotional support both to patient and family
· Maintain good personal hygiene particularly skin care
Diagnostic Exams:
1. Nose and throat swab
2. Schick’s test
3. Molony test
Treament:
1. AntiiDiphtheria Serum (ANST)
Nursing Management:
· Absolute bed rest
· I & O measurement
· Keep patient warm
· Care of tracheotomy
Prevention:
· Mandatory DPT immunization of babies
· Children under 5 years old should receive diphtheria-tetanus
vaccine
· Concurrent and terminal disinfection
· Isolation for at least 14 days from onset until 3 N & T swab
are negative
Bull Neck Tonsilar Diphtheria
Who should & should not receive DPT
2. Intestinal
ü Vomiting
ü Fever
ü Obstinate constipation or diarrhea
3. Nervous form
ü Headache and fever
ü Terrific muscular and joint pain
ü Profound prostration
Complications
1. Related viral infection
a) Hemorrhagic pneumonia
b) Encephalitis
c) Myocarditis
d) Sudden death in infants
2. Super imposed bacterial infection
a) Otitis media
b) Sinusitis
c) Pneumonia
Nursing Management;
ü Stay at home
ü Plenty of fluid intake
ü Antipyretics
ü Hydrotherapy
ü Isolation
ü Limit strenuous activities activities
ü Watch out for complications
Preventive Measures
ü Immunization
ü Avoidance of crowded places
u Personal hygiene
PERTUSSIS
(Whooping Cough)
1. Catarrhal stage
ü Coryza, lacrimation and dry cough
ü Cough becomes irritating, hacking and nocturnal
ü It is during this stage that the disease is very communicable
2. Paroxysmal stage
ü Occurs on the 7th – 14th day
ü Excessive explosive outburst of coughing about 5 – 10 rapid
coughs in one expiration
ü Paroxysmal coughing may induce nosebleed, increased
venous pressure, periorbital edema, and conjunctival
hemorrhage.
ü Violent coughing usually is accompanied by profuse
sweating.
Involuntary urination, lethargy, and exhaustion
ü Cough is provoked by crying, eating, drinking , or physical
exertion
ü Convulsion may occur due to cerebral hemorrhage
ü This stage lasts for 4 - 6 weeks
3. Convalescent stage
ü Gradual decrease in patoxysms both in frequency and
severity
COMPLICATIONS
1.Interstitial pneumonia
2. Atelectasis
3.Umbilical hernia
4. Otitis media
5 Bronchopneumonia
6. Severe malnutrition and starvation
DIAGNOSTIC EXAM
1. Nasopharyngeal swab
2. Sputum culture
3. CBC ( leukocytosis)
Modalities of Treatment:
1. Supportive therapy
ü Fluid and electrolyte replacement
ü Adequate nutrition
ü Oxygen therapy
2. Antibiotics
3. Hyperimmune convalscent serum
Nursing Management:
1. Isolation and medical asepsis
2. Provide quiet environment
4. Sunshine and fresh air
5. Warm baths preferred
6. Monitor intake and output
Prevention:
1. Any case of pertussis should be reported
2. Public education regarding massive immunization of DPT
PNEUMONIA
Ø An acute infectious disease characterized by general toxemia and the
consolidation of one or more lobes of either one or both lungs
Ø Caused by several organisms, and or other noxious substances
ü Bacteria
ü Viruses
ü Mycoplasma
ü Various chemicals
Pathology:
1. Stage of lung engorgement
ü Dark red in color
ü Exuding a bubbly, blood-tinged froth
2. Red hepatization
ü Looks like a piece of red granite
3. Gray hepatization
ü More softer and tears more easily
ü When pressed, exudes a purulent fluid
4. Stage of resolution
ü Inflammatory exudates are either expectorated or absorbed
the blood stream
Diagnostic Exam:
1. Physical findings
2. Chest x-ray
3. Sputum analysis, culture, smear
4. Blood/serologic exam
Modalities of Treatment:
1. Antimicrobial therapy
a) Streptococcus – Microlides
b)
Klebsiela - minoglycosides and cephalosporin
c) Streptococcu - Nafcillin/oxacillin
d) Pneumocystis - Co-trimozasole
e) Pen G still the drug of choice
2. Bronchodilators
3. Expectorants
4. Pain relievers for pleuritic pain
Nursing Management:
· Maintain patent airway and adequate oxygenation
· Teach patient how to cough and do deep breathing exercises
· Maintain adequate nutrition
· Proper disposal of sputum
· Control temperature by cooling measures
· Monitor vital signs closely, watch for danger signs like;
ü Marked dyspnea
ü Irregular, thready pulse
ü Delirium with extreme restlessness
ü Cold, moist skin
ü Cyanosis and exhaustion
Prevention:
· Hib – anti-haemophilus influenza B
· Pneumonia vaccine (PCV)
· Prevent common colds, influenza, and other upper respiratory
infection
TUBERCULOSIS
(Consumption Dse.; Koch’s Dse.; Phthisis)
Clinical Classification
1. Inactive
· Symptoms of TB are absent
· Sputum negative for TB bacilli
· No evidence of cavity on chest x-ray
2. Active
· Positive Tuberculin test
· Chest x-ray reveal progressive activity
· Symptoms are present
· Sputum and gastric content positive for tubercle bacilli
3. Activity not determined
Clinical Manifestations
· Afternoon rise of temperature
· Night sweating
· Body malaise and weight loss
· Cough, dry to productive
· Dyspnea, hoarseness of voice
· Hemoptysis
· Occasional chest pains
· Sputum positive for AFB
Diagnostic Exam
1. Ask for medical history
2. Physical exam
3. Chest x-ray
4. Microbiologic test
5. Tuberculin test
Treatment Modalities
1. SCC –Short Course Chemotherapy (6 months)
R – Rifampicin
I – Isoniazid
P – Pyrazinamide
E - Ethabutol
4. DOTS
Elements of DOTS
1. Sustained political commitment –
· increase financial and human resources
2. Access to quality-assured TB sputum microscopy
· Case detection of persons presenting symptoms of TB
· Screening of individuals
· Health education about quality-assured sputum microscopy
3. Standard short-course chemotherapy to all cases of TB
· Direct observe of treatment
4. Uninterrupted supply of quality-assured drugs
· Sustained supply of anti-TB drugs
· Establish a reliable system of regular distribution of anti-TB
drugs
· Anti-TB drugs should be available FREE to all TB patients
· Reduce non-adherence to treatment and prevent the
development of MDR
5. Recording and reporting system
· Monitors treatment and progress outcome of individual
patient
· Evaluate overall program performance
Nursing Management:
Prevention:
a) Massive BCG immunization
b) Avoid overcrowding
c) Good personal hygiene and environmental sanitation
d) Improved nutritional status
SARS
Ø First reported in China in Nov. 2002
Ø Caused by Corona virus
Ø Transmitted by respiratory droplets or direct contact with
fomites
Ø Contamination of materials or objects by respiratory secretions
or body fluids
Ø Virus is stable in urine for 1 – 2 days and in stool for 4 days in
urine at room temperature
Ø Survives on paper, walls for 36 hours and in plastic surfaces for
72 hours, and glass surfaces for 96 hrs.
Ø Virus loses infectivity after exposure to common disinfectants
Ø Heat of 55 ° C rapidly kills the virus
Signs and Symptoms:
Preventive Measures:
· Fecal - oral:
· Direct contact – sexual contact by orogenital, oroanal,
proctogenital sexual activity.
· Indirect contact –by ingestion of food specially uncooked leafy
vegetables or contaminated with fecal material
containing E. hystolitica cysts
· Are passed out with formed or semi-formed stools and are resistant
to environmental conditions
· Can remain viable and infective in moist an cool environment for
at least 12 days, and in water for 30 days.
· They are resistant to all levels of chlorine normally used for
water purification
· They are rapidly killed by temprature below 5 and above 40
degrees centigrade
· Considered as the infective stage in the life cycle of E. hystolitica
· Cyst pass to the large imtestines and htch into trophozoites. Pass
into the mesenteric veins, to the portal veins, to the liver, thereby
forming amoebic abscess.
Clinical Manifestations:
A. Acute amoebic dysentery
· Slight attack of diarrhea, altered with periods of constipation and
often accompanied by tenesmus
· Diarrhea, watery and foul-smelling stools often containing
blood-streaked mucus
· Colic and gaseous distension of the lower abdomen
· Nausea, flatulence and abdominal distension, and tenderness in the
right iliac region over the colon.
B .Chronic amoebic dysentery
· Tenesmus accompanied by the desire to defecate
· Anorexia, weight loss and weakness
· Liver may be enlarged
· The stools at first are semi-fluid but soon become watery,
bloody, and mucoid
· Vague abdominal distress, flatulence, constipation or irregularity
of the bowel.
· Abdomen lost its elasticity when picked – up between fingers.
· On sigmoidoscopy, scattered ulceration with yellowish and
erythematous border.
· The gangrenous type (fatal cases) is characterized by the
appearance in the stools of large sloughs of intestinal tissues
accompanied by hemorrhage.
3. Extraintestinal forms:
Hepatic
· Pain at the upper right quadrant with tenderness of the liver
· Jaundice
· Intermittent fever
· Abscess may break through the lungs, patient coughs anchovy-sauce
sputum
Diagnostic Exam:
1. Stool exam (cyst, pus white and yellow with plenty of amoeba)
2. Blood exam (leukocytosis)
3. Proctoscopy / Sigmoidoscopy
Treatment modalities:
Methods of prevention:
1. Health education
2. Sanitary disposal of feces
3. Protect, chlorinate and purify drinking water
4. Use scrupulous cleanliness in food preparation and handling
5. Detection and treatment of carriers
6. Fly control (they can serve as vector)
BACILLARY DYSENTERY
(Shigellosis; Bloody flux)
1. Shigella boydii
2. Shigella connei
3. Shigella flesneri (group B) common in the Philipines
4. Shigella dysenterae
Clinical manifestations
· Fever, specially in children
· Tenesmus, nausea, vomiting and headache
· Colicky or cramping abdominal pain associated with anorexia
and body weakness
· Diarrhea with bloody-mucoid stools that at first is watery
· Dehydration and loss of weight is rapid
Complications
· Rectal prolapse particularly in undernourished children
· Respiratory complications, such as cough and pneumonia
· Non-suppurative arthritis and peripheral neuropathy
Diagnostic Procedure
· Fecalysis or microscopic examination of the stools
· Isolation of the causative organism from rectal swab or culture
· Peripheral blood examination
· Blood culture
Nursing Management
· Maintain fluid and electrolyte balance to prevent profound
dehydration
· Restrict food until nausea and vomiting subsides
· Isolation; can be carried out through medical aseptic technique
· Maintain personal hygiene
· Proper disposal of excreta
· Concurrent and terminal disinfection.
1. Initially, the stools are brown and contain fecal materials but
soon become pale gray, “rice-water” in appearance with an
inoffensive, slightly fishy odor.
4.. Tissue turgur is poor, eyes are sunken into the orbit.
5. The skin is cold, the fingers and toes are wrinkled, assuming
the characteristic “washer-woman’s-hand”
7. Cyanosis is present
8. The voice become hoarse and then, is lost, so that the patient
speaks in whisper (aphonia)
12. When the patient is in deep shock, the passage of diarrhea stops
13. Death may occur as short as four (4) hours after onset, but usually
occurs on the first or the second day if not properly treated
Principal Deficits:
Diagnostic Exams:
1. Rectal swab
2. Darkfield or phase microscopy
3. Stool exam
Modalities of Treatment:
1. Intravenous treatment – this is achieved by rapid intravenous
infusion of alkaline saline solution containing sodium, potassium,
chloride and bicarbonate ions in proportions comparable to those
in water-stools.
2. Oral therapy – rehydration can be completed by oral route
(ORESOL, HYDRITES) unless contraindicated or, if the patient is
not vomiting.
3. Antibiotics
a. Tetracycline 500 mg every 6 hours for adults, and 125 mg/kg
body weight for children every 6 hours for 72 hours.
b. Chloramphenicol – 500 mg for adults and 18 mg/kg for
children every 6 hrs. for 72 hours.
c. Co-trimoxazole – 8mg/kg for 72 hours.
Nursing Management:
Prevention:
· Protection of food and water supply from fecal contamination.
· Water should be boiled or chlorinated
· Proper preparation and storage of food
· Milk should be pasteurized
· Sanitary disposal of human excreta
· Environmental sanitation
HEPATITIS A
(Infectious hepatitis; Catarrhal jaundice)
Treatment modalities
· No specific treatment, although bed rest is essential
· High carbohydrate, low fat, low protein diet
· Vitamin supplement specially the B complex group
· Intravenous therapy is occasionally necessary
· Isoprinosine (methisoprenol), may enhance the cell-mediated
immunity of the T- lymphocytes
· Administer alkalies, belladonna, and anti-emetics to control
dyspepsia and malaise
Nursing management
· Isolation of the patient (enteric isolation)
· Promote rest during acute or symptomatic phase
· Improve nutritional status
· Utilize appropriate measures to minimize spread of the disease
· Check stools for presence of blood
· Provide optimum skin and oral care
· Increase in ability to carry out activities
· Encourage gradual resumption of activities and mild
exercise during recovery
ü Carriers – could be one who recovered from the disease or one who
have cared for a patient with Typhoid and was infected.
ü Ingestion of shellfish (oysters) taken from waters contaminated by
sewage disposal
ü Stool and vomitus of infected individual
Mode of Transmission
· Fecal-oral transmission
· Organism can be transmitted through the five (5) F’s
· Ingestion of contaminated food, water and milk
Pathogenesis
I. Typhoid Ileitis
Salmonella thyphi
Bowel (Peyer’s patches)
Clinical Manifestations
I. Onset
· Headache, chilly sensation, aching all over the body,
· Nausea, vomiting and diarrhea
· By the 4th and 5th day all symptoms are worst
· Fever is higher in the morning than it was in the afternoon.
Temperature graph appears “ladder – like or stairway”
· Breathing is accelerated, the tongue is furred, the skin is dry
and hot, abdomen is distended and tender
· Rose spots appear on the abdominal wall on the 7th to the 9th day
· On the second week symptoms become more aggravated.
Temperature remains in uniform level. Rose spots become more
prominent.
II. Typhoid State
· Intense symptoms decline in severity
· The tongue protrudes, become dry and brown
· Teeth and lips accumulate a dirty-brown collection of dried
mucus and bacteria known as sordes.
· Coma vigil
· Subsultus tendinum
· Carphologia
· There is constant tendency for the patient to slip down to the foot
part of the bed
· In severe cases rambling delirium sets in often ending in coma
& death
Complications
· Bronchitis and pneumonia
· Meteorism or excessive distention of the bow-
els (Tympanites)
· Thrombosis and embolism
· Early heart failure
· “Typhoid spine” or neuritis
· Septicemia
· Reiter”s syndrome – joint pain, eye irritation,
painful urination that
can led to chronic arthritis
Diagnostic Procedure
· SEIA – Salmonella Enzyme Immuno-Assay
· Typhidot
· ELISA
· Widal test
· Rectal swab
Modalities of Treatment
· Chloramphenicol – drug of choice
· Ampicillin
· Co-trimoxazole
· Ciprofloxacin or Ciftriaxone
Nursing Management
· Maintain or restore fluid and electrolyte balance
· Monitor patient’s vital signs
· Prevent from further injury (fall) in patient with typhoid
psychosis
· Maintain good personal hygiene and mouth care
· Cooling measures during febrile state
· Watch for signs of intestinal bleeding
1. Schistosoms japonica
· Infects the intestinal tract (Katayama Disease)
· Found to be the only type that is endemic in the Philippines
· This is also known as “Oriental schistosomiasis”.
2. Schistosoma mansoni
· Also affects the intestinal tract
· Common in some parts of Africa
3. Schistosoma haematobium
· Affects the urinary tract
· Can be found in some parts of the Middle East, like Iraq, Iran
Ø An acute, contagious exanthematous disease usually affect children
which are referable to Upper Respiratory Tract Infection (URTI)
Ø Caused by a filtrable virus that belongs to genus Morbilivirus of the
family paramyxoviridae.
Ø Incubation period: 10 – 12 days; single attack conveys lifetime immunity
Ø Period of communicability
· Measles usually lasts about 9 – 10 days, measured from the
beginning of the prodromal symptoms to the fading of the rash.
· The disease is communicable 4 days before and 5 days after the
appearance of rashes
· The disease is most communicable during the height of rash
Ø Sources of infection: Patient’s blood, nasopharyngeal secretions and secre
tions from the eyes
Transmitted
· Direct contact by droplets spread through coughing or sneezing
· Indirectly, through articles or fomites freshly contaminated with
respiratory secretions of infected patients
I. Pre-eruptive stage
· Fever
· Catarrhal symptoms (Rhinitis, coryza, conjunctivitis, photophobia)
· Respiratory symptoms – starts from common colds to persistent
coughing (metallic/brassy cough)
· Enanthem sign (Koplik spot, Stimson’s line)
II. Eruptive stage
· The rash is usually seen late in the 4th day
· Maculo-papular rash
· High grade fever that comes on and off
· Abdominal tympanism, pruritus, lethargy
· The throat is red and often extremely sore.
· As fever subsides, coughing may diminish, but more often it
hangs on for a week or two, become looser and less metallic.
Modalities of treatment
Complications
· Bronchopneumonia
· Otitis media
· Pneumonia/Bronchitis
· Encephalitis; encephalo-myelitis
· Blindness (seldom)
Unfavorable Signals
· Violent onset with high grade fever
· Fading eruption with rising fever
· Hemorrhagic or black measles
· Persistence of fever 10 days or more
· Slight eruptions accompanied by severe symptoms, especially
those of encephalitis
Nursing Management
· Isolation (quiet, well ventilated, subdued light in patient’ room)
· Control high temperature with warm or tepid sponges
· Skin care.
· Oral and nasal hygiene
· Care of the eyes.
· Care of the ears.
· Daily elimination is important.
· During the febrile stage, limit the diet to fruit juices, milk, and
water..
· Patient’s position should be changed every 3 to 4 hours
Preventive measures
Immunization with:
Ø A mild viral illness caused by rubella virus. associated with a rash,
and aches in joints, that usually has a teratogenic effect on the fetus.
Prevention
· Administration of live attenuated vaccine (MMR)
· Pregnant women should avoid exposure to patients infected with
Rubella
· Administration of Immune Serum Globulin one week after
exposure to Rubella.
EXANTHEM SUBITUM
(Roseola infantum; Rose Rash of Infants)
Ø A benign disease that occur almost exclusively in infants and young
adults
Treatment:
ü Symptomatic
ü No isolation needed
CHICKENPOX
(Varicella)
HERPES ZOSTER
(shingles)
Evolution of Macule
rashes Papule Same
Vesicle
Pustule
I. Dengue fever
· Fever and chills associated by severe frontal headache, ocular pain,
myalgia with severe backache, and arthralgia
· Nausea and vomiting
· Fever is non-remitting and persist for 3 – 7 days
· Rash is more prominent on the extremities and the trunk. It may
involve the face in some isolated case
· Petechiae usually appear near the end of the febrile period and
most common on the lower extremities.
II. Dengue Hemorrhagic Fever (DHF)
Grade I
Fever accompanied by non-specific constitutional symptoms and the
Only hemorrhagic manifestation is positive (+) tourniquet test.
Grade II
All signs of grade I plus spontaneous bleeding from the nose, gums,
GIT
Grade III
Presence of circulatory failure as manifested by weak pulse, narrow
pulse pressure, hypotension, cold clammy skin and restlessness
Grade IV
Profound shock, undetectable blood pressure and pulse
Complications:
1. Dengue Fever
1. Epistaxis; menorrhagia
2. Gastrointestinal bleeding
3. Concomitant gastrointestinal disorder (peptic ulcer)
2. D H F
1. Metabolic acidosis
2. Hyperkalemia
3. Tissue anoxia
4. Hemorrhage into the CNS or adrenal glands
5. Uterine bleeding may occur
6. Myocarditis
3. Severe manifestations
1. Dengue encephalopathy – manifested by increasing restlessness,
apprehension or anxiety, disturbed
sensorium, convulsions, spacity,
and hyporeflexia
Diagnostic Tests:
2. Tourniquet test – screening test, done by occluding the arm veins
for about 5 minutes to detect capillary fragility
2. Platelet count (decreased) – confirmatory test
3. Hemoconcentration – an increase in at least 20% in hematocrit or
steady rise in hemartocrit
4. Occult blood
5. Hemoglobin determination
Treatment Modalities:
Period of Communicability
· Untreated or insufficiently treated patient may be source of mosquito
nfection for more than 3 years in P. malariae; 1 – 2 years in P. vivax,
and not more than one year on P. falciparum.
Mode of Transmission
· Rapid diagnostic test (RDT) – are blood tests for malaria that can
be conducted outside the laboratory and in the field, giving a
result within 10 – 15 minutes. This is done to detect malarial
parasite antigen in the blood.
Means of propagation:
1. Sexual – takes place in the stomach of mosquito
2. Asexual – takes place in the RBC of man
Management
1. Medical
· Anti-malarial drugs
= Chloroquine (all species except for P. malariae)
= Quinine/Quinidine
= Sulfadoxine for resistant P. falciparum
= Primaquine – for relapse of P. vivax and ovale
P. Falciparum Regimen
D1 _ Chloroquin 4 tabs
Sulfadoxin 3 tabs
D2 – Chloroquin 4 tabs
D3 - Chloroquin 2 tabs
D4 – Primaquin 3 tabs
P. Vivax Regimen
D1 – Chloroquin 4 tabs
D2 – Chloroquin 4 tabs
D3 – Chloroquin 2 tabs
Relapsing
D1 – Coartem 20/120 (Artemether Lumefantrine)
– 4 tabs
The microscopic worms pass from the mosquito through the skin and travel
to the lymph vessels where they grow into adults, and live in 7 years in the
lymph vessels
· The disease damage the kidneys and the lymph system; fluid collects
and causes swelling in the arms, breasts, legs, and for men, the genital area.
· A person with this disease tend to have more bacterial infections in the
skin, thus, causes hardening and thickening of the skin, which
is called elephantiasis.
· In conjunctival filariasis, the worms’ larvae migrate to the eye and
sometimes can be seen beneath the conjunctivae, that can lead to
blindness known as onchoceriasis
Symptoms:
· Infections usually begin with chills, headache, and fever between
three months and one year after the insect bite.
· There may also be swelling, redness, and pain in the arms, legs, or
scrotum.
· Areas of abscesses may appear as a result of dying worms or a
secondary bacterial infection.
Complications
1. Recurring infections, fevers, severe inflammation of the lymph system
2. Lung condition called Tropical Pulmonary Eosinophilia (TPE).
3. The legs become grossly swollen .that can lead to severe disfigurement,
decreased mobility, and long-term disability.
4.Testicular hydrocele is a disfiguring enlargement of the scrotum.
Diagnostic Procedures:
· Circulating Filarial Antigen (CFA) test – performed on a finger-prick
blood droplet taken any time of the day and gives result in a few minutes
Modalities of Treatment.
1. Ivermectin,
2. Albendazole, or
3..Diethylcarbamazine (DEC) – used to treat by;
· Eliminating the larvae
· Impairing the adult worms ability to reproduce
· By actually killing the adult worms
LEPTOSPIROSIS
Mode of Transmission
· Ingestion or contact with the skin and mucous membrane with the infected
urine or carcasses of wild and domestic animals
· Through the mucous membrane of the eyes, nose, and mouth, and
through a break on the skin
· Leptospira enters the blood stream to cause damage on the kidneys,
the liver, meninges and conjunctivae.
Clinical Manifestations
1. The symptoms range from severe to asymptomatic fatal outcome
2. Clinical course is generally biphasic and the majority of the cases are
unicteric. In icteric cases, typical color of the eyes is- orange
3 Three stages can be recognized:
2. Nursing
a. Isolate the patient, urine must be properly disposed
b. For home care, cleaning near dirty places, pools, and stagnant water
c. Eradicate rats and rodents
Complications:
1. Biliary tract obstruction, patient develops cholestatic jaundice
2. Hepatic abscess and cholangitis
3 Intestinal obstruction, perforation, peritonitis
4. Malnutrition – due to damage to the intestinal mucosa impairing the
absorption of nutrients
Diagnostic tests:
Pathology
· The larvae penetrate the blood and lymph vessels, damaging them in the process
after which they enter the inferior vena cava to the right atrium, to the lungs where
they pierce the capillary walls and pass into the alveoli.
· Some maybe coughed out and expectorated, while some are swallowed
and reach the small intestine where maturation occurs and egg production
takes place.
Symptoms
· They feed on the host’s blood and may consume 50 ml of blood daily.
The gradual loss of blood results in iron deficiency anemia
· Other symptoms include abdominal pain, diarrhea, and allergic reactions
like urticaria
· Children infected with worms are often underdeveloped mentally and
physically, have protruding abdomen, and are lethargic
· They tend to be malnourished and undersized
· They are lazy, have no energy, and lack ambition
· Many of them have perverted appetite
· Pedal edema and other portion of the body maybe present
Diagnosis
· Microscopic examination of feces for the eggs
· Blood exam reveals eosinophilia
Modalities of Treatment
· Pyrantel embonate (Quantrel)
· Tetrachloroethylene
· Carbon tetrachloride
Nursing Management
· Isolation is not necessary
· Diet – should be high in calories, vitamins and minerals.
· Personal hygiene should be maintained
Prevention
· Health education on the proper disposal of excreta
· Regulations to prevent the pollution of streams and lakes with human excreta
should be adopted
· All persons in areas where hookworm is endemic should avoid going barefoo
· Good hygiene is extremely important
· Animals should not be allowed to defecate on the streets or places
where people most likely linger
LIFE CYCLE OF HOOKWORM
LEPROSY
(Hansen’s Disease; Hansenosis)
1. Lepromatous leprosy
· The most serious type and considered to be the most infectious
· Causes damage to the respiratory tract, eyes, and testes as well as the
nerves and the skin
· Lepromin test is negative but the skin lesion contain large amount of
Hansen’s bacillus
· There is a gradual thickening of the skin with the development of
granulomatous condition.
· The lesions frequently appear as macules, becoming nodular in
character (leproma).
· There is slow involvement of the peripheral nerves, with some degree
of anesthesia and loss of sensation and gradual destruction of the nerves.
· There is atrophy of the skin and muscles and eventual absorption of small
bones, primarily the bones of the hands and feet.
· There is ulceration of the mucous membrane of the nose
· Because of absorption of small bones and ulcerations, natural amputation
may occur.
2. Tuberculoid leprosy
· Affects peripheral nerves and sometimes the surrounding skin, specially on
the face, eyes, and testes as well as the nerves and the skin.
· Lepromin test is positive, but the organism is rarely isolated from the lesions.
· Macules are elevated with clearing at the center and are more clearly defined
than in the lepromatous form
· Anesthesia is present, and involvement of the peripheral nerves occur more
rapidly than in the lepromatous form
3. Borderline (dimorphous) leprosy – has characteristics of both lepromatous
and tuberculoid. Skin lesions in this type are diffused and poorly defined
Clinical Manifestations:
1. Clawhand, footdrop, and ocular manifestations, such as corneal
insensitivity and ulceration, conjunctivitis, photophobia and blindness
2. Lepromatous leprosy can invade tissues in every organ of the body
3. In lepromatous disease, early lesions are multiple, symmetrical and
erythematous, sometimes appearing as macules or papules with smooth
surfaces.
4. Later, these lesions enlarged and form plagues on nodules on the earlobes,
nose, eyebrows, and forehead, giving the patient a leonine appearance.
5. Loss of eyebrows and eyelashes
6. Loss of function of sweat and sebaceous glands
7. Epistaxis, ulceration of the uvula and tonsils, septal perforation and nasal
collapse
SEXUALLY TRANSMIT-
TED DISEASES
Definition :
Signs/Symptoms
1. Persistent cough for one month
2. Generalized pruritic dermatitis
3. Recurrent herpes zoster
4. Generalized lymphadenopathy
5. Prolong fever
6. Loss of weight
Four “C’s” in the management of HIV/AIDS
1. Compliance
2. Counseling
3. Contact tracing
4. Condom
SYPHILIS
* A sexually transmitted disease caused by a bacterium
Treponema pallidum, the great imitator
C. Latent
Ø No clinical symptoms occur but serologic test
proved reactive
D. Congenital syphilis
Ø Fetus become infected and is expelled from the
uterus either as miscarriage, or stillbirth
Ø Stillborn may have macerated appearance with
collapse of the skull and protuberant abdomen
Ø The skin is red, with a number of bullae filled with
hemorrhagic fluid
Diagnostic Tests:
a) Dark field illumination test – most effective if moist
lesions are present
b) Fluorescent treponemal antibody absorption test-
exudates from lesions
c) VDRL – slide and rapid plasma test
d) CSF analysis
Drug of Choice:
a) Pen G Benzathine 2.4 million units/week x 3 weeks
b) Tetracycline or Dopxycycline (contraindicated for
pregnant women)
Nursing Management:
a) Instruct patient to abstain from sexual contact
while on treatment
b) Stress the importance of completing the treatment
c) Practice Universal/Standard precaution
d) Report all cases to health
Prevention:
a) Control of prostitution
b) Requiring health workers for regular check up
c) Proper sex education
d) Case finding
Congenital Syphilis
Adult Syphilis
GONORRHEA
(Clap. Gleet, Flores blancas)
Mode of Transmission:
1. Contact with exudates of infected persons
2. Direct contact with vaginal secretions during delivery
3. Sexual contact
4. Through fomites
Signs/Symptoms:
A) Female:
1. Burning and frequent urination
2. Yellowish purulent vaginal discharge
3. Burning and itching of the vaginal area
4. Urethritis andcervicitis, endometriutitis, salphingitis
5. Pregnant women may infect the eye of her baby
during delivery
B) Males
1. Dysuria with purulent discharge (gleet) From
urethra 2 – 7 days after exposure
2. Rectal infection
3. Prostatitis
4. Pelvic pain and fever
Complications:
1. Sterility
2. Arthritis
3. Endocarditis
4. Conjunctivitis
5. Meningitis
Treatment:
1. For uncomplicated gonorrhea – Ceftriaxone 125-250
mg IM single dose; Doxycycline 100mg BID x 7 days
2. Pregnant women – Ceftriaxone 125-250 mg IM as
single dose plus erythromycin 500mg orally x 7 days
3. Acqueous procaine penicillin 4 million units IM ANST
GENITAL HERPES
CANDIDIASIS
THE END