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  • Enzymology PPT 3

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    Alanine aminotransferase (ALT) catalyzes the transfer of an amino group from alanine to form pyruvate and glutamate. It is located primarily in the liver but also found in kidney, skeletal muscle, and heart muscle. ALT measurement is used clinically to detect and diagnose liver disease. Gamma glutamyl transpeptidase (GGT) maintains cysteine levels in the body and is located in the liver, kidney, and pancreas. GGT testing is used to detect liver dysfunction, slight cholestasis, and pancreatic cancer.

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    Biochemistry

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    Enzymology ppt 3

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    Alanine aminotransferase (ALT) catalyzes the transfer of an amino group from alanine to form pyruvate and glutamate. It is located primarily in the liver but also found in kidney, skeletal muscle, and heart muscle. ALT measurement is used clinically to detect and diagnose liver disease. Gamma glutamyl transpeptidase (GGT) maintains cysteine levels in the body and is located in the liver, kidney, and pancreas. GGT testing is used to detect liver dysfunction, slight cholestasis, and pancreatic cancer.

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    8 views3 pages

    Enzymology PPT 3

    Uploaded by

    amina tahir amina tahir
    Alanine aminotransferase (ALT) catalyzes the transfer of an amino group from alanine to form pyruvate and glutamate. It is located primarily in the liver but also found in kidney, skeletal muscle, and heart muscle. ALT measurement is used clinically to detect and diagnose liver disease. Gamma glutamyl transpeptidase (GGT) maintains cysteine levels in the body and is located in the liver, kidney, and pancreas. GGT testing is used to detect liver dysfunction, slight cholestasis, and pancreatic cancer.

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    of 3

    AIZA KHALID

    2020-AG-7021
    ALANINE AMINOTRANSFERASE

    Alanine aminotransferase catalyzes the transfer of an amino


    group from alanine to alpha-ketoglutarate in the alanine
    cycle to form pyruvate and glutamate.
    • Location in liver and significant concentrations are also found
    in kidney, skeletal muscle, and myocardium.
    • The primary clinical application of serum ALT measurement is
    the detection and diagnosis of hepatic disease.
    GAMMA GLUTAMYL TRANSPEPTIDASE

    • (GGT) is essential to maintaining cysteine levels in the


    body.
    • GGT activity is localized in liver, kidney, and pancreas tissues.
    • Application
    This test is done for liver dysfunction.
    This test can detect the slightest degree of cholestasis.
    GGT is a good marker for pancreatic cancer.

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