Coulter principle

Camila Cárdenas
Diego Castiblanco
María Paz Ussa
Mateus Vitta
 Theory

2023
Universidad de la Sabana
The Coulter principle states that particles pulled through an orifice, concurrent with an electric current,
produce a change in impedance that is proportional to the volume of the particle traversing the orifice.

Applications
Hematology Cell count and size

Count of blood cells, including their If a cellulose solution is isotonic and

volume and their size, having in count the conducts electricity the Coulter counter
different particles that can be present in will be able to measure the cells and
blood their size 
 Experimental considerations

Coincidence Particle path

Anomalous electrical
pulses can be generated. 01 02 The disturbance in the electric field is
proportional to the volume of electrolyte
displaced from the aperture.

Porous particles
The shape of the generated 0 Conductive particles
electrical pulse varies with the 03 The voltage used should be
particle path through the
aperture.
4 below the breakdown potential.

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