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CCBS 3

IMMUNOLOGY
INTRODUCTION
 Immunity is the state of having sufficient biological
defenses to avoid infection, disease, or other
unwanted biological invasion.

 It
is the capability of the body to resist harmful
microbes from entering it.

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IMMUNE SYSTEM
ORGANS
Acquired Immunity INNATE IMMUNITY
(specific) (NON-SPECIFIC)

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INNATE VS ADAPTIVE IMMUNITY
Humoral Immunity Cellular Immunity

Type of cells B-Cells T-Cell

Antibody Involvement Yes No

Location of pathogen Extracellular Intracellular

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MAJOR HISTOCOMPATIBILITY
COMPLEX (MHC)
• The Major Histocompatibility complex (MHC) is a large
genomic region or gene family found in most vertebrates.
• It is the most gene-dense region of the mammalian genome
and plays an important role in the immune system,
autoimmunity, and reproductive success.
MHC 1 & 2
ANTIBODY STRUCTURE AND
FUNCTION

Fragment crystallizable region


IMMUNOGLOBULIN ISOTYPES
ACUTE-PHASE REACTANTS
COMPLEMENT
IMPORTANT CYTOKINES
INTERFERON-Α AND -Β

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