POLYMER MATERIALS:

BIOMEDICAL AND SUSTAINABLE
ASPECTS (C004139) - AL PART
Peter Dubruel
Academic year 2022-2023

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POLYMER NETWORKS: HYDROGELS AL

AS CASE STUDY

AL1: Terminology of (poly)saccharides

AL2: Prominent amino acids in gelatin

AL3: Nomenclature of Pluronics

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POLYMER NETWORKS: HYDROGELS AL

AS CASE STUDY
AL1: Terminology of (poly)saccharides    

- Fisher?
- C1?
- stereo-isomers?
- D versus L?

- anomeric C-atom?
neutral linear polysaccharide
- 1,3 versus 1,4
of alternating (1,3)-linked β-galactopyranose and (1,4)-
linked 3,6-anhydro-α-galactopyranose units
- α versus β

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POLYMER NETWORKS: HYDROGELS AL

AS CASE STUDY
AL2: Prominent amino acids in gelatin    

- glycine: cfr. close packing

- (hydroxy)proline: cfr. restriction of conformational freedom  

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POLYMER NETWORKS: HYDROGELS AL

AS CASE STUDY
AL3: Nomenclature of Pluronics    

- F127
- solid
- hydrogel-forming

- F127:  12 x 300 g/mol = 3600 g/mol                            

              ± MM PPO
- F127:  7 x 10 = 70% 
             wt% PEO in F127                     0.7 x 12570 g/mol = 8799 g/mol  

- [EO]100-[PPP]65-[EO]100     in reality:   MM PPO = 3770 g/mol, MM PEO = 4400 g/mol, MM F127 = 12570 g/mol
                               
                                   
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POLYMERS FOR DENTAL APPLICATIONS

AL4: Shrinkage during radical polymerisation

AL5: Synthesis polysulphones, polyethersulphones and polycarbonates

AL6: What makes a metal hydrophylic?

AL7: Synthesis of bismethacrylate for dental apps

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POLYMERS FOR DENTAL APPLICATIONS

AL4: Shrinkage during radical polymerisation

- liquid monomers -----> solid material -----> density change -----> reduction in overall volume

- solution?             

AL5: Synthesis polysulphones, polyethersulphones and polycarbonates

- PES: see chapter on "Polymers for filtration applications"

- PC: bisphenol-A + phosgene

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POLYMERS FOR DENTAL APPLICATIONS

AL6: What makes a metal hydrophylic?

- some metals contain an oxide top layer    

AL7: Synthesis of bismethacrylate for dental apps

- synthesis? : bisphenol A + glycidylmethacrylate