Professional Documents
Culture Documents
• Staphylococcus spp
• Gram-Negative Enteric Bacilli
• Pseudomonas aeruginosa
epidemiologia:
• Yyvelaze xSiria zrdasrulebSi:
o studentebi, romlebic cxovroben saerTo sacxovrebelSi
o samxedroebi
epidemiologia:
• Conjugate polysaccharide Haemophilus influenzae
type b vaccine introduced in 1991
• Heptavalent pneumococcal conjugate vaccine
introduced in 2000
o Covers 80% of invasive serotypes
o Projected to prevent 12,000 cases/year
MENINGOCOCCAL VACCINES
• 5 Major Serogroups Cause Disease
o A, B, C, Y, W-135
• Polysaccharide vaccines effective for groups A, C,
Y, W-135 in older children & adults
• Poor response in young children
• No vaccines of serogroup B
MENINGOCOCCAL VACCINES
• Conjugation of polysaccharide vaccine to a protein
carrier increases efficacy in infants and young
children
• Conjugate serogroup C vaccine in use in UK since
1999: very effective in young children
• Conjugate vaccine for A, C, Y & W-135 under
development
MENINGOCOCCAL VACCINES
• Use for 1st Year College Students Controversial in
the Past
o No cost savings
Low # of cases
High cost of vaccination
o From individual perspective, may be worthwhile
MENINGOCOCCAL VACCINES
2005 AAP RECOMMENDATIONS
• Administer MCV4 to
o 11-12 year olds, especially if at increased risk
o Students entering high school or at age 15
o College freshmen who will be living in dormitories
paTofiziologia:
• hematogenuri gavrceleba
o qalas fuZis motexiloba
o gavrceleba mezobeli struqturebidan: yuri, sinusebi, orbitebi
o iatrogenuli
paTofiozologia:
• paTologiuri cvlilebebi ganpirobebulia:
o TviTon gamomwvevis zemoqmedebiT
o imunuri pasuxiT infeqciaze
simptomebi:
• Kklasikuri niSnebi:
o Tavis tkivili
o fotofobia
o kisris kunTebis rigidoba
o cnobierebis Secvla
o daWimuli yiflibandi
o gulisreva
o Rebineba
meningialuri gaRizianebis niSnebi:
o kisris kunTebis rigidoba:
o Brudzinski Sign:
o Kernig Sign:
o bavSvebi xSirad ewinaaRmdegebian ar undaT siaruli
an xelSi ayvana
o am niSnebis ar arseboba ar gamoricxavs
meningitis diagnozs
o axalSobilebSi da mcire asakis bavSvebSi
informatiuli ar aris
SYMPTOMS OF BACTERIAL
MENINGITIS
ROTHROCK
Clinical Feature Untreated (175) Pretreated (83)
cxeleba 82-96%
leTargia 17-95%
Wirveuloba 18-40%
Rebineba 20-100%
daWimuli 18-40%
yiflibandi
Bbaqteriuli meningitis niSnebi:
gulyra 4-23%
Ffokaluri 5-6%
Nnevr. niSnebi
Bbaqteriuli meningitis niSnebi:
rigidoba 27-95%
Kernig’s Sign 0-36%
Brudzinski’s 10-83%
> 1 meningiuri 26-93%