PRESENTED BY Ms. Aruna Jadav ANKYLOSING SPONDYLITIS DEFINITION
Ankylosis spondylitis is a chronic
inflammatory disease that primarily affects the axial skeleton. It leads to pain , stiffness and fusion of spine.
It effects sacroiliac joints, intervertebral disc
spaces and costovertebral articulations. AREAS MOST COMMONLY AFFECTED:- The Spine Neck Ribs Shoulder Joints Hips Thighs Joints of the Hands and Feets ETIOLOGY / RISK FACTORS The exact cause is unknown. Genetics And Family History Age Sex (more develop in men rather than women) Infection (bacteria, fungi, virus) PATHOPHYSIOLOGY Due to Etiology and Risk factors Autoimmune response occurs
Inflammation of joints and surrounding tissues
Pannus ( granulation tissue) formation that
destroy the bone and cartilage
Calcification and fusion of articular tissue
PATHOPHYSIOLOGY
Joint fusion and Immobility
LUMBER LOST CURVED SHAPE CLINICAL MANIFISTATION Pain in lower back, buttocks, hips or down the legs. Stiffness in lower back, hips and buttocks ( during night and morning) As disease progresses – lumber lost the curve shape and impair mobility. Other symptoms include fever, fatigue, anorexia and weight loss. STIFFNESS AND IMPAIR MOBILITY DIAGNOSTIC EVALUATION History collection Physical Examination CBC (Complete blood count) CRP (C- reactive protein) ESR (Erythrocyte Sedimentation Rate ) X-Rays MRI Scan INVESTIGATION COMPLICATION Spine related issues (nerve roots situated in bottom of the spinal cord as the damage vertebrae may cause problems in bladder/bowel control, loss of reflexes etc. Uvetitis (eye inflammation with light sensitivity and blurry vision. Cardiac issues UVETITIS MANAGEMENT Medical Management Non steroidal Anti-Inflammatory drugs (NSAIDS) Ex. Indomethacin used to treat stiffness. Topical corticosteroids (Ex. Sulfasalazine or Methotrexate. Anti-TNF (Tumor necrosis Factor)- Ex. Infliximab adalimumab may be effective to reduce inflammation. Physiotherapy to improve range of motion and posture. PHYSIOTHERAPY SURGICAL MANAGEMENT Artificial joint replacement surgery(Arthroplasty) Spinal Osteotomy (a surgical procedure in which a section of the spinal bone is cut and removed to allow for correction of spinal cord) ARTIFICIAL JOINT REPLACEMENT SPINAL OSTEOTOMY NURSING MANAGEMENT Acute pain related to vertebral and joint inflammation as evidenced by pain scale. Activity intolerance related to vertebral and joint inflammation and pain as evidenced by verbalization, generalized weakness, fatigue Impaired physical mobility related to vertebral and joint inflammation as evidenced by severe pain, verbalization.