What Are The Surgical

Complications Of Typhoid Organism

• Enteric fever is an acute systemic infection with a
protracted course caused by Salmonella typhi.
• Mode of transmission is faeco-oral
• Common in areas with poor sanitation and limited
availability of clean portable water.
• Usually managed by the physicians but the surgeon is
called when complications of surgical importance arise.
• The surgical complications of typhoid fever are a
significant cause of morbidity and mortality.
• It is a common disease with a annual
incidence of 21million cases.
 Aetiology
• The infection is caused by the bacteria,
Salmonella typhi,
• A gram-negative rod found only in humans,
and
• Rarely by Salmonella paratyphi.
 Pathophysiology
• The more common surgical complications
include:
• intestinal perforation; intestinal bleeding;
cholecystitis (perforation, empyema);
osteomyelitis; and abscesses.
• Rare surgical complications include
pancreatitis, hepatic and splenic abscesses,
pleural effusion, and orchitis.
• Week 1 - ingestion of contaminated
food/water.
• Bacteria in small intestine
• Passes through the payer’s patches into the
circulation and reaches various organs by this
route
– Osteomylitis
– Abscesses
• Week 2 – bacteria excreted in bile some pass into the
gallbladder, where they multiply and remain
– Invasion of the gallbladder wall
– cholecystitis
• Reaches the terminal ileum, invade peyer’s patches, and
multiply there (at this stage it is excreted in the stool)
• Week 3 – necrosis and ulceration of the peyer’s patches
occurs.
– Intestinal perforation
– Intestinal bleeding
 Clinical Presentation
• History
• The symptoms include:
• Fever and general body weakness:
• Abdominal pain usually begins 2–30 days (median
= 9 days)5 after the onset of fever.
• Abdominal distention can be observed.
• Diarrhoea or constipation: Diarrhoea may occur in
the early stages, but constipation sets in later in
the course of the illness.
• Passage of blood in the stool may occur, either
as frank or altered blood.
• Jaundice may be a complaint.
• Pain at the site of the abscess or osteomyelitis.
 Physical Examination
• These patients are usually very ill; common
findings include dehydration, pyrexia, pallor
and wasting.
• Jaundice may be present.
• Shock may also be present, as evidenced by
tachycardia and hypotension
• Abdominal/rectal examination
• Evaluation/Investigations
• Serum electrolytes, urea, and creatinine:
• Plain radiography:
• Abdominal ultrasonography:
• Microbiological cultures:
• FBC:
• Widal test:
• Further investigations:
• Management
• Correct fluid and electrolyte deficits:
• Nasogastric decompression:
• Urethral catheter:
• Blood transfusion:
• Antibiotic therapy:
• Definitive Treatment
• Intestinal Perforation
• The surgical options are:
• Segmental resection of affected intestine
• Simple closure of perforations
• Enterostomy
• Cholecystitis
• Intestinal Bleeding
• Osteomyelitis
• Abscesses