Roadmap for Research

on Antimicrobial Resistance
in Indonesia

ORGANISASI RISET KESEHATAN

BADAN RISET DAN INNOVASI NASIONAL
 Regulation and References on
Antimicrobial Resistance (AMR)
• Peraturan Menteri Koordinator Bidang Pembangunan Manusia dan Kebudayaan
Republik Indonesia nomor 7 tahun 2021 tentang Rencana Aksi Nasional Pengendalian
Resistensi Antimikroba tahun 2020-2024

• The recommendations of the 68th World Health Assembly in 2015, Member States are
urged to develop strategies and plans on the implementation of AMR control

• A one health priority research agenda for antimicrobial resistance (World Health
Organization, Food and Agriculture Organization of the United Nations, United Nations
Environment Programme and World Organisation for Animal Health, 2023)
 Introduction
• Antimicrobial resistance (AMR) is an increasing threat to public health and sustainable
development.

• The increasing emergence and spread of AMR compromises our ability to treat infections and
to manage AMR-associated economic impacts across all sectors.

• Infectious diseases caused by multiple drug resistant organisms (MDRO) have become more
worrying at the national and global levels. Several MDRO causing infections in hospitals are
Enterobacteiacear, Pseudomonas spp., Acinetobacter spp., Staphylococcus spp.,

• Indonesia uses more antibiotics, partly due to increasing income, low-cost antibiotics, lack of
control over the use of antimicrobials in hospitals, and sales of over-the- counter drugs.
 Antimicrobial Resistance Issues

• Antimicrobials are still used inappropriately, excessively, and imprudently in humans, animals,
and plants.
• Antimicrobial resistance has the potential to impede various national development programs in the
sector of disease control and food security.
• Infectious disease treatment failure due to antimicrobial resistance has become an issue for public
health and animal health, resulting in an increased burden on public health and animal health
funding.
• Antimicrobial resistance control is still performed on a sectoral basis, thus it is not handled
optimally.
• Antibiotics are being sold without a doctor’s or veterinarian’s prescription.
 Highest-priority research areas

Highest-priority research areas

• Transmission
• Impacts the transmission of resistant microorganisms between humans, animals, plants and the environment in
Indonesia
• Integrated surveillance
• To do equality integrated AMR surveillance systems including Epidemiology, Molecular and Genomics surveillances
• To run existing AMR and AMU surveillance data from humans, animals, plants and the environment in different regions in
Indonesia
• Interventions
• One Health interventions approach for AMR control and mitigation most effectively
• The systematic collection and analysis of data for risk assessment and intervention impact assessment (epidemiological,
economic, social)
• Behavioural insights and change
• Structural challenges and barriers to behaviours related to AMR be identified, characterized and assessed in different
socio cultural contexts and regions in Indonesia
• Economics and policy
• One Health AMR socioeconomic impact assessment based on accurate and cost-effectively collected data
• To identify, prioritize and institutionalize the most relevant cross- cutting, sector-specific AMR policy options and
regulatory frameworks, and financing strategies
 Roadmap of Integrated AMR Research
Center in Indonesia
Building referral
Building AMR laboratory Exploration of
laboratory: AST dan
and data Center capacity antimicrobial agents in
Genomic
Indonesia
Building integrated AMR Transmission of resistant Research Center for
surveillance systems microorganisms ”one health AMR in Indonesia
approach”

AMR surveillance in humans, One Health AMR AMR policy, regulatory

animals, plants and the socioeconomic frameworks, and
environment impact financing strategies

AMU surveillance in humans, Challenges and

animals, plants and the barriers to behaviours
environment related to AMR
Interlinkage of different data types for
actionable public health results