Professional Documents
Culture Documents
Homeostasis
Chapter 14
Pages 393-404
Chapter 2
(34-38)
Learning Outcomes
In simple words, homeostasis is the state of steady internal, physical, and chemical
conditions maintained by living systems.
Physiological homeostasis
Physiological homeostasis is the
tendency of the body to maintain
critical physiological parameters (e.g.,
blood glucose level, blood pressure,
core body temperature etc.) of its
internal environment within specific
ranges of values.
Impact of homeostatic imbalance
● Many diseases are a result of homeostatic imbalance, an inability of the body to restore a functional, stable
internal environment.
● Aging is a general example of disease as a result of homeostatic imbalance. As an organism ages, results in an
unstable internal environment. This lack of homeostasis increases the risk for illness and is responsible for the
physical changes associated with aging.
● Diseases that result from a homeostatic imbalance include heart failure and diabetes, but many more examples
exist.
● Diabetes occurs when the control mechanism for insulin becomes imbalanced, either because there is a
deficiency of insulin or because cells have become resistant to insulin.
Quizizz
Spinal cord injury and pressure sores
● Individuals with SCI are at high risk for developing pressure sores.
Up to 80% of individuals with SCI will have a pressure sore during their lifetime,
and 30% will have more than one pressure sore.
● Most pressure sores are preventable.
Causes
Extrinsic:
○ Too much pressure on the skin for too long (see notes)
○ Shearing occurs when the skin moves one way and the bone underneath it
moves another way. This can result from slouching while sitting, sitting at a 45°
angle (as in bed), or sliding during a transfer instead of lifting your body.
Shearing can also happen during spasms.
○ Trauma of any kind (cuts, bumps, burns, scrapes, rubbing)
○ Abrasion or friction: Cut or scratch; sliding across sheets or transfer board with
bare skin.
○ Bump or fall: Bumping toes into doorways; bumping your buttocks off the tire
during transfers; bumping knees under desks.
○ Immobilisation and inappropriate equipment (bed, pressure relief mattress,
chair without cushions etc.)
Causes contd..
Intrinsic: