You are on page 1of 62

Agenda

Transdiagnostic Issues With ADHD


Transdiagnostic Research Domains
Transdiagnostic Cognitive Dysfunction
Transdiagnostic Cognitive Dysfunction
What About Cognition and Aging?
IQ and ADHD
ADHD and Depression
Prevalence of Probable ADHD Increases in
Advanced Treatment Stages of MDD
Cognitive Symptoms Impact Workplace
Impairment
“A Compound Which Stimulates 5-HT1A and Blocks 5-
HT3”
Effects of Life, Medications, and Sleep on
Processing Speed Measured by DSST
Vortioxetine in Real-World Clinical Practice
Cognitive Change During MDD Treatment
High Genetic Loading for Schizophrenia
At 7 Years Old!
Muscarinic Cholinergic Receptor Agonist and
Peripheral Antagonist for Schizophrenia
Improving Cognition in Psychotic Illness
The Primary Wechsler Intelligence Scale for
Children-V (WISC-V) Scales
A Case for Diagnostic Achromatopsia:
Comorbidities or ADHD?
Mood and Anxiety Disorders Not Responding
to Treatment?
ADHD May Be Hiding in the Background
Underreporting by Adults With Childhood
History of ADHD
Pittsburgh ADHD Longitudinal Study
Underdiagnosis
Overlooked and Nonreferred
Biologic Systems, Neurotransmission, and
Networks in ADHD
Joined at the Root
Genetic Composition of Psychiatric Disorders
Polygenic Risk for ADHD and Associated
Traits
Relationship Between Genetic Risk for
ADHD and Important Clinical and Functional
Outcomes
Phenotypic-Genetic Similarity
Emotional Dysregulation May Be a
Manifestation of Genetic Risk
for ADHD
Associations of PGS With Childhood, Persistent,
and
Late-Diagnosed ADHD
Functional Brain Networks in ADHD
Stronger Connection Between DLPFC and
DMN Correlates With Impaired Attention in
ADHD
Symptoms of Depression Reflect Aberrant
Functional Network Connectivity in MDD
Altered Functional Network Activity in
Anxiety Disorders
5-HT and DA Have a Role in Networks
Associated
With ADHD
Catecholamine Regulation of PFC Activity and Sensory
Circuits
Reflective to Reactive
Catecholamine Regulation of Prefrontal Cortex, Limbic and Paralimbic
Areas
Serotonin Regulation of Brain Network
Function
Monoamines Modulate Information
Processing Arc in the Brain
Inputs and Outputs of Monoaminergic Nuclei
Evidence of Emotional Dysregulation in
ADHD
Summary
Case Discussions
Older FDA-Approved Medications With
Clinical Data for Adults
With ADHD
Serdex/d-MPH
Long-Term Efficacy 1-Year Open-Label Study
70/30 Serdex/d-MPH
AEs
Transdermal d-Amphetamine Patch
Transdermal d-Amphetamine Patch AEs
Viloxazine XR Short-Term and Long-Term
Adult Data
AEs of Viloxazine in Adults
Efficacy of Amphetamine Extended-Release
Tablets in Adults
With ADHD
Safety of Amphetamine Extended-Release
Tablets in Adults
With ADHD
Melissa B
Melissa B
Expert Discussion
Carmen M
Carmen M
Carmen M
Expert Discussion

You might also like