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  • 1.3 Respons Op Acute Inspanning Bij Obesitas

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    This document summarizes some of the physiological effects of obesity on the body during exercise. It finds that while obese individuals may not have lower maximal oxygen consumption (VO2peak) when expressed in ml/min, they universally have lower VO2peak when expressed in ml/kg/min due to the increased weight. It also discusses disturbances in muscle function, hormonal levels, lipolysis, cardiovascular function, and pulmonary function that can occur in obese individuals during exercise. These include increased ratings of perceived exertion during weight-bearing exercise, lowered fat oxidation capacity, disruptions in hormones like leptin and adiponectin, impaired ability to break down fat from adipose tissue, increased risk of high blood pressure and other cardiovascular

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    1.3 Respons op acute inspanning bij obesitas

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    This document summarizes some of the physiological effects of obesity on the body during exercise. It finds that while obese individuals may not have lower maximal oxygen consumption (VO2peak) when expressed in ml/min, they universally have lower VO2peak when expressed in ml/kg/min due to the increased weight. It also discusses disturbances in muscle function, hormonal levels, lipolysis, cardiovascular function, and pulmonary function that can occur in obese individuals during exercise. These include increased ratings of perceived exertion during weight-bearing exercise, lowered fat oxidation capacity, disruptions in hormones like leptin and adiponectin, impaired ability to break down fat from adipose tissue, increased risk of high blood pressure and other cardiovascular

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    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
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    7 views16 pages

    1.3 Respons Op Acute Inspanning Bij Obesitas

    Uploaded by

    sten.kuyken
    This document summarizes some of the physiological effects of obesity on the body during exercise. It finds that while obese individuals may not have lower maximal oxygen consumption (VO2peak) when expressed in ml/min, they universally have lower VO2peak when expressed in ml/kg/min due to the increased weight. It also discusses disturbances in muscle function, hormonal levels, lipolysis, cardiovascular function, and pulmonary function that can occur in obese individuals during exercise. These include increased ratings of perceived exertion during weight-bearing exercise, lowered fat oxidation capacity, disruptions in hormones like leptin and adiponectin, impaired ability to break down fat from adipose tissue, increased risk of high blood pressure and other cardiovascular

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
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    of 16

    Exercise physiology in internal diseases: obesity

    Prof. dr. Dominique Hansen


    dr. Charly Keytsman
    Prof. dr. Chris Burtin
    Physical fitness
     Lowered VO2peak?

     Not every obese person is deconditioned per se


     When expressing VO2peak in ml/min

     Every obese person is deconditioned


     When expressing VO2peak in ml/kg/min
    Muscle function

    Tanner CJ, et al. Am J Physiol 2002; 282: E1191


    Muscle function

    Biolo G, et al. Clin Nutr 2014; 33; 737


    Muscle function

     Muscle overload during walking/running

     Increased RPE Borg especially during weight-


    baring exercises
    Muscle function

     Lowered fat oxidation capacity

    Percentage of plasma free fatty acid (FFA) uptake oxidized during basal and exercise (50% maximum O2
    consumption). *Significantly decreased in extremely obese and extremely obese subjects after weight reduction
    (weight-reduced) compared with lean (P < 0.05).

    Houmard J A Am J Physiol Regul Integr Comp Physiol 2008;294:R1111-R1116


    Hormonal disturbances

    Mittendorfer et al. Am J Physiol 2004


    Hormonal disturbances

    Vettor R, et al. Acta Diabetol 1997; 34: 61


    Hormonal disturbances

    Goodpaster B, et al. Obes Res 2002; 10: 575


    Disturbed lipolysis

    Cedric Moro
    Adapted from: Hansen D, Exercise therapy in adult individuals with obesity. 2013, Nova Science Publishers, NY, USA
    Adipocyte physiology
    Disturbed lipolysis

    Mittendorfer B, et al. Am J Physiol 2004; 286: E354


    Cardiovascular disturbances

    Adapted from: Hansen D, Exercise therapy in adult individuals with obesity. 2013, Nova Science Publishers, NY, USA
    Gondoni et al. Nutr Metab Cardiovasc Dis 2008
    Cardiovascular disturbances

    Salvadori A, et al. J Clin Basic Cardiol 1999; 2: 229


    Pulmonary disturbances

    Santiago Lorenzo and Tony Babb


    Adapted from: Hansen D, Exercise therapy in adult individuals with obesity. 2013, Nova Science Publishers, NY, USA
    Pulmonary disturbances

    Could lower PaO2 during exercise

    Santiago Lorenzo and Tony Babb


    Adapted from: Hansen D, Exercise therapy in adult individuals with obesity. 2013, Nova Science Publishers, NY, USA

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