PEPTIC ULCER

PRESENTED BY
HAFSA NAVEED
22-MC-084
PEPTIC ULCER

 An excoriated area of
stomach or intestinal
mucosa caused
principally by the
digestive action of
gastric juice or upper
small intestinal
secretions
 Types Of Peptic Ulcer

1- Gastric Ulcer -
Ulcers that develop inside the stomach.
2- Esophageal Ulcer -
Ulcers that develop inside the esophagus.
3- Duodenal Ulcer -
Ulcers that develop in the upper section of the
small intestines, called the duodenum
 Marginal Ulcer

 A type of peptic ulcer called a

marginal ulcer also often occurs
wherever a surgical opening such as
a gastrojejunostomy has been
made between the stomach and the
jejunum of the small intestine.
 Basic Cause of Peptic Ulceration

A peptic ulcer can be caused in either of two ways:

1. Excess secretion of acid and pepsin by the gastric mucosa

2. Diminished ability of the gastroduodenal mucosal barrier to protect against the digestive
properties of the stomach acid–pepsin secretion
Gastric Protective Factors
Duodenal Protective Factors
Physiology Of Treatment

(1) Use of antibiotics along with other agents to kill infectious

bacteria

(2) Administration of an acid-suppressant drug H2 Blocker—

ranitidine H+ pump inhibitor– omeprazole Surgical
intervention is required if ulcer perforates or bleeds.
Thank You !