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    Wasan Mismar
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    James B. Sumner discovered that enzymes are proteins and developed a method to crystallize enzymes. In 1926, he was the first to isolate and crystallize the enzyme urease from jack beans, which was widely believed to be impossible at the time. His findings were ridiculed and ignored for several years, particularly by German chemist Richard Willstätter. John H. Northrop later isolated another enzyme in 1930, proving Willstätter wrong and validating Sumner's work.

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    James B. Sumner discovered that enzymes are proteins and developed a method to crystallize enzymes. In 1926, he was the first to isolate and crystallize the enzyme urease from jack beans, which was widely believed to be impossible at the time. His findings were ridiculed and ignored for several years, particularly by German chemist Richard Willstätter. John H. Northrop later isolated another enzyme in 1930, proving Willstätter wrong and validating Sumner's work.

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    Biology - Enzymes

    Uploaded by

    Wasan Mismar
    James B. Sumner discovered that enzymes are proteins and developed a method to crystallize enzymes. In 1926, he was the first to isolate and crystallize the enzyme urease from jack beans, which was widely believed to be impossible at the time. His findings were ridiculed and ignored for several years, particularly by German chemist Richard Willstätter. John H. Northrop later isolated another enzyme in 1930, proving Willstätter wrong and validating Sumner's work.

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    Wasan Mismar 11G Biology

    Enzymes
    Question 3 p.85

    Investigate Sumners work and discover which scientists were particularly against his ideas and why ? James B. Sumner
    American chemist James B. Sumner discovered the protein nature of enzymes, and developed a general crystallization method for enzymes. In 1926 he became the first scientist to isolate and crystallize an enzyme, urease, found in the Canavalia ensiformis jack beans. As this was widely believed to be impossible, his finding was ridiculed and ignored for several years, particularly by the famed German chemist Richard Willsttter. In 1930 John H. Northrop was able to isolate another enzyme, proving Willsttter wrong and Sumner right. In 1937 Sumner isolated and crystallized a second enzyme, catalase, found in blood. He shared the 1946 Nobel Prize for Chemistry with Northrop and Wendell M. Stanley.

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