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3rd lecture
By Dr. Mudassar Ali Roomi (MBBS, M. Phil)
CARDIAC MUSCLE
SMOOTH MUSCLE
Single central nucleus. Intercalated discs / gap junctions are at the level of Z membranes. (Diad)
Single central nucleus. In some places (intestine), randomly distributed thick & thin filaments interdigitate. Fewer mitochondria. Mostly glycolytic metabolism.
Few mitochondria. Major source of energy is CHO. Glycolysis Citric acid cycle.
More mitochondria (25% mass). Major source of energy is fat (60%) at rest.
Myelination Schwann cells surround the nerve axon forming a myelin sheath Sphingomyelin decreases membrane capacitance and ion flow 5,000-fold Sheath is interrupted every 1-3 mm : node of Ranvier
Saltare: to jump Node to node conduction. Internodes are myelinated and act as insulators. Myelin sheath is absent at the nodes of Ranvier & neurilemma at the nodes has got ion channels.