Drug Generic Name: Ceftriaxone Brand Name: Rocephine Classification: Third- generation cephalosporin pregnancy risk category B, Antiinfectives

Dosage, Route and Frequency Dosage: 1g Route: IVTT Frequency: Q12

Mechanism of Action Third generation cephalosporin that inhibits cell wall synthesis, promoting osmotic instability; usually bactericidal.

Indications Uncomplicated gonoccocal vulvovaginitis

Contraindications

Adverse Effects

Nursing Responsibility

- Contraindicated in patients hypersensitive to drug or other UTI; lower respiratory cephalosporins. tract, bone or joint, intra-abdominal, or - serious skin structure infection; hypersensitivity to septicemia. penicillin; Meningitis Pre-operative prevention Acute bacterial otitis media hyperbilirubinemic neonates (may lead to kernicterus) - renal impairment

CNS: fever, dizziness, Before administering headache drug, ask patient if he is allergic to CV: phlebitis penicillin, or cephalosporin GI: diarrhea, Obtain specimen for pseudomembranous culture and colitis sensitivity test before giving first GU: genital pruritus, dose. candidiasis Instruct patient to take medication around Hema: thrombothe clock and to cytosis, eosinophilia, finish the leukopenia medication completely, even Skin: pain, feeling better. induration, tenderness Advise patient to report at injecton site, rash, signs of pruritus superinfection (furry over-growth on the tongue, vaginal itching or discharges, loose foul smelling stools) and allergy.