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AnkylosingSpondylitis(AS)isachronicinflammatorydiseasethatcausesarthritisofthespine, andotherlargejoints.Thisconditioncausesinflammationofthespinaljointswhichcanleadto persistentpainandstiffnessfromtheneckdowntothelowerback.Insomecasesthebonesin thespinemayfusetogether,resultinginarigidspineandleadingtoastoopedoverposture. ASisasystemicdisease,meaningsymptomsmaynotbelimitedtothejoints.Patientswiththis conditionmayalsoexperiencefever,fatigue,andlossofappetite.Somepatientswithankylosing spondylitishaveinflammationoftheeyeandinrarecases,lungandheartproblemsmay develop. Signsandsymptomsofankylosingspondylitistypicallybegininearlyadulthoodandthe conditionsismoreprevalentamongmenthanwomen.ThereisnocureofAS;thegoalof treatmentistoreducepain,preventdeformitiesandimprovefunction.

SymptomsofAnkylosingSpondylitis Themostcommonearlysymptomsinclude: Constantstiffeningandpaininthelowerbackandhips MorningStiffness LimitedMotion Symptomimprovementwithexerciseandunrelievedwithrest Jointpainintheknees,shoulders,upperback,ribcage,andfeet Eyeinflammation

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