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The name myasthenia gravis, which is Latin and Greek in origin, literally means "grave muscle weakness.

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Presented by:

Mohamed Abedkhalil Sheila Noakes Brandy Gidney Christina Martinez

Myasthenia gravis

Myasthenia gravis is a chronic autoimmune neuromuscular disease characterized by varying degrees of skeletal muscle weakness of the body.

occurs

in about 1 in 10,000 people

most commonly affects women under 40 and men over 60

ptosis (drooping eyelids diplopia (double vision) dysarthria (speech impairment) dysphagia (chewing and swallowing) weakness of arm or leg muscles myasthenia crisis (breathing difficulties)

neurological exam
blood test for serum antibodies to AChR

electromyogram (EMG)

anticholinesterase therapy
immunosuppressant therapy

thymectomy

usually not fatal life expectancy is usually normal lifestyle changes often help with daily activities

Medical/Scientific Advisory Board (M/SAB) exercise therapy study

National Institute of Neurological Disorders and Stroke funding a phase 3 trial for thymectomy

Myasthenia Gravis Foundation of America only national volunteer health agency in the United States dedicated solely to the fight against myasthenia gravis

Mohamed Abedkhalil diagnosed at age 3 managing daily tasks powertools mestinon

McKinley Michael, Valerie O'Loughlin and Theresa Bidle. Anatomy & Physiology: An Integrative Approach. New York: McGraw Hill, 2013 (1st Edition). Print http://www.mayoclinic.com/health/myasthenia-gravis/DS00375 http://www.merckmanuals.com/professional/neurologic_disorders/peripheral_nervous_ system_and_motor_unit_disorders/myasthenia_gravis.html

http://www.myasthenia.org/HealthProfessionals/ClinicalOverviewofMG.aspx
http://www.myasthenia.org/Research.aspx http://www.myasthenia.org/WhatisMG/TestDiagnosticmethods.aspx http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0001731/ http://www.ninds.nih.gov/disorders/myasthenia_gravis/detail_myasthenia_ gravis.htm#216503153 http://www.nlm.nih.gov/medlineplus/myastheniagravis.html

https://www.youtube.com/watch?v=vyQWGclkGWQ&feature=player_detailpage

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