Schematic Diagram Pathophysiology (Book-based) COPD and Tuberculosis

Non- Modifiable Factors

Age

Modifiable Factors Environment Work Smoking

Sex
Genetic Predisposition

Primary Infection

Inhalation m. tuberculae Infecting tuberculae bacilli phagocytosed Carried into regional broncho pulmonary lymnodes

Impaired lung clearance Bronchial inflammatory airway obstruction

Alveolar hypoventilation Weakened disruption Collapse of small airways in expiration

Necrotic degeneration Cavities filled with cheese mucus and dead blood cell

Drain into trcheobronchial tree Chronic bronchitis

emphysema