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A

Abnormal proliferation interferes


with normal hetopoiesis
Disruption in hematopoiesis
Disruption in
erythropoiesis
Disruption in
thrombopoiesis
Disruption in Leukocyte
formation
Decreased platelet
production
Increased risk for
bleeding, and
petechial bruising
Decreased normal
WBC production
Increased risk for
infection
Pallor Low HCT Low HGB
Decrease O2
circulating in the
body
Easy
Fatigabilty
Body weakness Shortness of Breath
Decreased RBC
production
Anemia
Bleeding gums


















B
Spillage of myeloblast in
bloodstream
Organ infiltration
CNS Liver Spleen Lymph
nodes
Increased ICP Hepatomegaly Spleenomegaly Lymphadenopathy




C
Increase number of
myeloblasts
Increase cellular demand for
nutrition
Depletion of
bodys normal
energy reserve
Weight loss Generalized
fatigue

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