LO 2

EPIDEMIOLOGY & RISK FACTOR

NEOPLASM

Epidemiology
Cancer incident (2002 in USA)
- Male : 30 % Prostat
14 % Lungs & Broncus
11 % Colon & rectal
- Female: 31 % Breast
12 % Lungs & Broncus
12 % Colon & rectal

Risk Factor
1. Age factor
- Most of the mortality from cancer occurs at
age 55-75 years.
- Cancer cause 10 % mortality in children <15
years old.
2. Geographic factor
e.g. Breast cancer in USA & Europe >> Japan
3. Environment factor
Foods, smoke, Alcohol, working environment

4. Hereditary
a. Hereditary cancer syndromes
b. Familial cancer
c. Recessive autosomal syndromes of DNA
repair disorder