Mebendazole

Mechanism of action
Mebendazole and thiabendazole block assembly of tubulin
polymers. By disrupting microtubule assembly, the formation
of mitotic spindles is disrupted. In addition, glucose uptake
into the parasite is disrupted with mebendazole, causing
worms to starve to death.
Clinical use
These drugs may be used to treat the enteric stages of pinworm,
roundworm, hookworm, and whipworm infections
but not larvae after they have migrated to muscle tissues.
Adverse effects
These drugs may cause gastrointestinal upset. In addition,
these agents are embryotoxic and should be avoided during
pregnancy