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  • Hyperthyroidis M: Increased Proliferation of Cathecholamines

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    Sergie Paul Fernandez
    11 views3 pages
    The document discusses hyperthyroidism, which occurs when there is excess thyroid hormone in the body from the thyroid gland. This causes a hypermetabolic state with increased metabolic rate and proliferation of catecholamines. Symptoms include palpitations, tremors, increased sweating, and eye changes. It also discusses how hyperthyroidism can contribute to osteoporosis in older women through increased bone resorption relative to formation. Finally, it notes that hyperthyroidism, along with obesity and genetic factors, can increase the risk of developing type 2 diabetes through mechanisms involving insulin resistance and secretion.

    Original Description:

    Pathophysiology of hyperthyroidism, DM, and Osteoporosis

    Original Title

    Path o Physiology

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    The document discusses hyperthyroidism, which occurs when there is excess thyroid hormone in the body from the thyroid gland. This causes a hypermetabolic state with increased metabolic rate and proliferation of catecholamines. Symptoms include palpitations, tremors, increased sweating, and eye changes. It also discusses how hyperthyroidism can contribute to osteoporosis in older women through increased bone resorption relative to formation. Finally, it notes that hyperthyroidism, along with obesity and genetic factors, can increase the risk of developing type 2 diabetes through mechanisms involving insulin resistance and secretion.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    11 views3 pages

    Hyperthyroidis M: Increased Proliferation of Cathecholamines

    Uploaded by

    Sergie Paul Fernandez
    The document discusses hyperthyroidism, which occurs when there is excess thyroid hormone in the body from the thyroid gland. This causes a hypermetabolic state with increased metabolic rate and proliferation of catecholamines. Symptoms include palpitations, tremors, increased sweating, and eye changes. It also discusses how hyperthyroidism can contribute to osteoporosis in older women through increased bone resorption relative to formation. Finally, it notes that hyperthyroidism, along with obesity and genetic factors, can increase the risk of developing type 2 diabetes through mechanisms involving insulin resistance and secretion.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    of 3

    Presence

    of
    Thyroid
    stimulati
    ng Ig

    Thyroid
    Gland
    Excess Thyroid
    Hormone (T3
    and T4)
    Decreased TSH

    HYPERTHYROIDIS
    M

    Hypermetabol
    ic State

    Sympathetic
    Activity

    Increased
    general
    metabolic rate

    Increased
    proliferation of
    cathecholamines

    Increased
    overall BMR

    Sympathomimet
    ic effect
    Ocular:
    PROPTOSIS
    CNS
    overstimulation:
    TREMORS
    GIT

    INCREASED
    SWEATING

    Cardiac
    Effects
    Increased HR
    and
    Contractility

    Increased
    Cardiac
    Output

    Peripheral
    vasodilation
    due to heat load

    PALPITATION
    AND
    TACHYCARDIA

    Multifactorial
    Factors: Old-aged
    woman, nutritional

    Inadequate
    intake of dietary
    calcium and Vit.
    D

    HYPERTHYRODI
    SM

    Age-related loss
    (in the 4th decade)
    Calcitonin
    PTH, Vit D.

    Decreased
    estrogen
    (postmenopausal)

    Imbalance
    between bone
    resorption and
    breakdown
    Reduced bone mass,
    deterioration of bone matrix,
    and diminished bone
    architectural strength

    Osteoporosis

    DEXTROSCOLIO
    SIS AND
    KYPHOSIS

    Environmenta
    l Factors: High
    fat/lack of
    exercise

    Obesity

    Hyperthyroidi
    sm

    Insulin
    resistance

    Genetic
    Predisposition
    (both parents)

    Interaction

    Decreased insulin
    secretion

    Relative insufficiency of insulin


    action

    Development of type 2
    diabetes

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