June 17, 2015

Date
Evelyn Delmundo, RN, MaN, PhD.
Submitted to:
BSN IV-I
Villador, Mizchelle A.
Alcantara, Virginia Marie Q.
Submitted by:

BLASTEMA THEORY
College of Nursing

VISION
y through quality instruction and relevant research and development activities. It shall produce professional, s
A premier university in historic Cavite recognized for excellence in the development of m

Republic of the Philippines

CAVITESTATEUNIVERSITY
Don SeverinoDelas Alas Campus
Indang, Cavite

BLASTEMA THEORY
The theory was developed in 1838 by Johannes Murell, which demonstrates that a cancer
is made up of a cells and not lymph. Cancer cells did not arise from normal cells; it arose from
budding of elements blastema between normal tissues.

BLASTEMA
Blastema is a mass of undifferentiated cells which is capable of growth differentiation. It
also refers to any zone of embryonic tissue that is still differentiating and growing into a
particular organ. The term is usually applied to the tissue that develops into kidney and gonads.

DIFFERENTIATION
In Embryology, differentiation refers to the process in embryonic development during
which unspecialized cells or tissues become specialized for particular functions. In the concept of
oncology, differentiation is the degree of similarity of tumour cells to the structure of the organ
from which the tumour arose. Tumours are classified as well, moderately, or poorly
differentiated; well-differentiated tumours appear similar to the cells of the organ in which they
arose; poorly differentiated tumours do not. Such classification is often of prognostic
significance and determines the grade of the tumour. Well differentiated tumours are low grade,
poorly differentiated tumours are high grade.

CONCLUSION:
Cancer is made up of cells and not lymphatic fluid. This theory emphasizes the beginning
or onset of cancer in correlation of concept of cell development.