San Beda College

COLLEGE OF NURSING
P.O. BOX 4457 1005 MANILA, PHILIPPINES TELEFAX: 735-6011 to 15 Loc. 4131
GENERIC NAME: Cefuroxime BRAND NAME:
Route of Administration: I.V Dosage: 750mg

ADVERSE
MODE OF INDICATIONS/ REACTIO DRUG NURSING
HEALTH
DRUG CONTRAINDICATIO NS TO INTERACTIO CONSIDERATIO
ACTION TEACHINGS
CLASS NS WATCH NS NS
OUT FOR

Antibiotic Cefuroxime binds to one or Contraindication: Diarrhea/lo 1. Use IV route for 1. Report lack of
more of the penicillin- Cefuroxime for ose stools, Probenecid de severe/life response,
Cephalospo binding proteins (PBPs) Injection USP and N&V, threatening persistent
creases renal
rin, second which inhibits the final Dextrose Injection abdominal infections such as diarrhea or 5&S
clearance of
generation transpeptidation step of
USP is pain. cefuroxime. septicemia, or in of anemia (SOB,
peptidoglycan synthesis in
bacterial cell wall, thus contraindicated in poor-risk clients, dizziness, pale
patients with known Large Potentially especially skin, etc.)
inhibiting biosynthesis and
arresting cell wall assembly allergy to the doses can Fatal: Nephrot inpresence of immediately.
resulting in bacterial cell cephalosporin group cause oxicity with shock.
death. of antibiotics. cerebral aminoglycosid
Solutions containing irritation 2. For direct IV,
es
dextrose may be and reconstitute 750
and furosemid
contraindicated in convulsion mg in 8 mL sterile
e.
patients with s; nausea, water; give over
hypersensitivity to vomiting, 3-5 min. For
corn products. diarrhoea, intermittent IV,
Indications: GI further dilute in
For the treatment of disturbanc 100 mL of
many different types es; dextrose or saline
of bacterial infections erythema solution; infuse
such as bronchitis, multiforme, over 30 min.
sinusitis, tonsillitis,
Stevens-
ear infections, skin
infections, gonorrhea, Johnson
and urinary tract syndrome,
infection epidermal
necrolysis.
Potentially
Fatal: Ana
phylaxis,
nephrotoxi
city,
pseudome
mbranous
colitis.