COLLEGE OF NURSING

RLE
NCM 1O7: CARE OF THE MOTHER, CHILD & ADOLESCENTS (WELL CLIENT)
DRUG STUDY #: 1

NAME: Maria Dianne B. Ulanday BSN2-B Group E Submitted to: Sir Benjie G. Peras RN, ICN, MAN DATE : November 11, 2023

NAME OF DRUG
DOSAGE / ROUTE/ FREQUENCY ACTION ADVERSE EFFECTS CONTRAINDICATION NURSING CONSIDERATIONS
BRAND/GENERIC
Generic name: Cefuroxime Significant: Elevated INR (in Assessment
Brand names: nutritionally deficient • History: Hepatic and renal
patients; renal or hepatic impairment, lactation,
Cefuroxime is a 2nd disease, prolonged use), pregnancy
Known hypersensitivity (e.g.,
generation bacterial or fungal anaphylaxis) to cefuroxime • Physical: Skin status, LFTs,
cephalosporin which superinfection with prolonged axetil or to other β-lactams renal function tests, culture
Uncomplicated skin and skin structure binds to 1 or more of use, including Clostridium (e.g., penicillins and of affected area, sensitivity
the penicillin-binding difficile-associated diarrhoea and cephalosporins).
tests
infections
proteins (PBPs) thereby pseudomembranous colitis;
Adult: 500 mg bid for 7 days. inhibiting the final Jarisch-Herxheimer reaction Cefuroxime (cefuroxime
(cefuroxime injection) injection) Interventions
transpeptidation step (following treatment of Lyme
for Injection USP and Dextrose • Culture infection, and
Altacef, Cefudyne, Cefuget, of peptidoglycan disease).
Injection USP is arrange for sensitivity tests
Cefumax, Cefurex, Cefuvex, synthesis in the Blood and lymphatic system contraindicated in patients with before and during therapy
Cimex/Cimex Plus, Ducef, Efrox, bacterial cell wall, disorders: Neutropenia, known allergy to the
Elixime, Eroxmit 500, Eroxmit thus interrupting cell eosinophilia, decreased Hb, if expected response is not
750, Harox, Kefox, Kefsyn/Kefsyn cephalosporin group of
wall biosynthesis, and leucopenia, thrombocytopenia. antibiotics. Solutions containing seen.
750, Medzyme/Medzyme Vial,
arresting cell wall Gastrointestinal disorders: dextrose may be • Give oral drug with food to
Profurex, RiteMED Cefuroxime,
Robisef, Roxicef S125/Roxicef assembly resulting in Diarrhoea, nausea, vomiting, contraindicated in patients with decrease GI upset and
S250/Roxicef, Roxime 500, bacterial cell lysis and abdominal pain. hypersensitivity to corn enhance absorption.
Theoroxime, Trigenna, Truxim, death. General disorders and
products. • Give oral drug to children
Viacef, Xefu, Zefuxim, Zegen, administration site conditions: Inj who can swallow tablets;
Zinace, Zinnat, Zocef/Zocef Hospi, site reaction (e.g. pain, crushing the drug results in
Zoltax/Zoltax,
thrombophlebitis). a bitter, unpleasant taste.
 COLLEGE OF NURSING
Teaching points
Oral drug
Investigations: Transient increase
of hepatic enzyme levels.
Nervous system disorders:
Headache, dizziness.
Skin and subcutaneous tissue
disorders: Skin rash, urticaria,
pruritus.
Potentially Fatal: Severe
hypersensitivity (anaphylactic)
reactions.
• Have vitamin K available
in case
hypoprothrombinemia
occurs.
• Discontinue if
hypersensitivity reaction
occurs.
• Take full course of therapy
even if you are feeling
better.
• This drug is specific for
this infection and should
not be used to self-treat
other problems.
• Swallow tablets whole; do
not crush them. Take the
drug with food.
• You may experience these
side effects: Stomach upset
or diarrhea.
• Report severe diarrhea with
blood, pus, or mucus; rash;
difficulty breathing;
unusual tiredness, fatigue;
unusual bleeding or
bruising; unusual itching or
irritation.