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Bio 181 Study Guide THE CELL CYCLE and CELL DIVISION Study Questions 1.

Distinguish between fission and mitosis. 2. Describe the four phases of the cell cycle. 3. What is G0? 4. Where are the checkpoints located in the cell cycle? What is the purpose of check points? 5. What is the function of kinase? 6. Where do Cyclins D and E function in the cell cycle? What is the role of cyclindependent kinase (Cdk) in the cell cycle? 7. Is phosphorylated retinoblastoma protein functional? Why or why not? 8. What are the phases of mitosis? What are the distinguishing features of each phase? 9. What are chromatids? How many chromatids does a homologous pair of chromosomes have? 10. What are homologous chromosomes? 11. Distinguish between mitosis and meiosis. 12. Distinguish between anaphase I and anaphase II of meiosis. 13. If a particular cell has 24 chromosomes in G1 how many chromosomes will the cell have in G2? How many chromatids will the cell have at metaphase (mitosis)? 14. What is the role of the centrosome in cell division? 15. What is the role of the centromere in mitosis? 16. When do chromatids separate in mitosis? When do chromatids separate in meiosis? Terms you should know: Anaphase Anaphase I Anaphase II Cell cycle Centromere Centrosome Chromatid Chromosome Cyclin Cyclin dependent kinase (Cdk) Cytokinesis Daughter chromosome Diploid Fission G0 G1 G2 Haploid

Histone protein Homologous chromosome Interphase M phase Meiosis Metaphase Metaphase I Metaphase II Mitosis Mitotic spindle p21 protein Pro-metaphase Prophase Prophase I Prophase II Retinoblastoma (RB) protein S phase Telophase

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