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NIPER DEMO PAPER 1

Q1. Diels Alder reaction is an example of

A. Cycloaddition reaction B. Pericyclic reaction C. Sigmatropic reaction

D. none of the above Q2. In Oxo process the catalyst used is

A. CO2 [Co8] B. CO2 [Co6] C. CO2 [Co 4]

D. none of the above Q3. Generally the particle size in suspension is (micrometer)
A. 10 1000 B. 100 1000 C. 10 100

D. can be of any size Q4. Flow Point can be defined as in case of

A. Emulsion B. Colloidal C. Suspension

D. none Q5. Indian Pharmacopoeia is published by

A. Ministry of Health and Family Welfare B. Deptt. Of Pharmaceuticals C. D.C.G.I

D. Ministry of Chemicals Q6. First Edition of Indian Pharmacopoeia was published in

A. 1955 B. 1966 C. 1985

D. 1976 Q7. Total number of enzyme involved in degradation of fatty acids are A. 5 B. 7 C. 9 D. 4

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Q8. Sulfonamides act by competing with PABA for the enzyme

A. Dihydroptreoate synthtase B. H. Pylori C. CAT

D. none Q9. Near IR range is at ( in micron)

A. 0.8 2 B. 2 15 C. 15 1000

D. none Q10. In IR spectra the stretching is due to A. change in symmetry of the compound B. change in bond angle of the compound C. change in bond strength of the compound D. change in bond lenght of the compound Q11. Various types of instruments used in IR except
A. Nerst glower B. Globar source C. Incandescent wire

D. Tungsten lamp Q12. Sulfonamides are given in combination with which one of the following drug in treatment of malaria
A. Trimethoprim B. Itraconazole C. Pyrimethamine

D. none Q13. Mechanism of drug resistance in sulfonamides is due t

A. Alteration in the binding sites B. Blockage of the pathways C. Reduction of drug uptake

D. Plasmid mediated Q14. Co Trimoxazole is combination of

A. Sulfasalazine and sulfadiazine B. Sulfadiazine and methotrexate C. Sulfadiazine and Sulfamethoxazole

D. Sulfamethoxazole and trimethoprim Q15. Bolometer is used in

A. UV B. NMR C. MS

D. IR

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Q16. Central Drug Laboratory (biological and microbiological samples are tested) is located at?
A. Kolkota B. Lucknow C. Kasauli

D. Delhi Q17. Central Research Institute (CRI) is located at? (sera, vaccine, antigen, antitoxin tests and Rabbies research)
A. Kolkota B. Lucknow C. Kasauli

D. Delhi Q18. Indian Veterinary Research Institute is located at?

A. Pune B. Izatnagar C. Kanpur

D. Ghaziabad Q19. What is the antonym of Allay?

A. Pacify B. Stimulate C. Moderate

D. Peter Out Q20. Phantom and Specter are ___________ ?

A. Synonyms B. Antonyms C. Idioms

D. None of the above Q21. Water act as

A. Nucleophile B. Electrophile C. Both

D. None Q22. Pure water is

A. 58.0 M B. 55.0 M

C. 55.56 M D. none Q23. Dissociation const. of water is

A. 2 x 10-16 mol/L B. 3 x 10-16 mol/L C. 1.8 x 10-16 mol/L

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Q24. Water is
A. Monopole B. Dipole C. Both

D. None Q25. Favorskii rearrangement is a conversion of A. - hydroxyl ester to - halo ester B. - halo ester to - hydroxyl ester C. - halo ester to ester D. none Q26. Curtius reaction is a conversion of A. Acylazide to isocynate B. Isocynate to acylazide C. Nitrile to acid D. None Q27. - Lactamase inhibitor is
A. Oxacillin B. Carbenicillin C. Ticarcillin

D. Sulbactam Q28. First line drug for meningitis is

A. Carbenicillin B. Sulbactam C. Amoxicillin

D. Ampicillin Q29. How many steps are common in gluconeogenesis and glycolysis
A. 6 B. 5 C. 7

D. 8 Q30. In glycogenesis formation of branching is done by the enzyme A. Fructose 6 phosphtase

B. C. Glucose 6 phosphtase Glucosyl 4- 6 transferase

D. None Q31. A sum of money amounts to Rs.8968/- in 3 years and Rs.9424/- in 4 years at 6% simple interest. What is the sum? A. Rs.7600 B. Rs.7700 C. Rs.7800 D. Rs.8000 For registration Contact:
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Q32. In 2009, Nobel Peace Prize A. Barack Obama B. Venkatraman Ramakrishnan, Thomas Steitz and Ada Yonath C. Herta Mueller D. Elinor Ostrom and Oliver Williamson Q33. In 2009, The Nobel Memorial Prize in Economic Sciences A. Elinor Ostrom and Oliver Williamson B. Elizabeth H. Blackburn, Carol W. Greider and Jack W. Szostak C. Herta Mueller D. Charles K. Kao, Willard S. Boyle and George E. Smith. Kao Q34. Central Drug Testing Laboratory (CDTL) is located at? A. Kanpur B. Chennai C. Delhi D. Bombay Q35. Indian Drug Manufacturing Association (IDMA) is located at? A. Kanpur B. Chennai C. Delhi D. Bombay Q36. Nujol mull is
A. Lipidic

B. Fat
C. Mineral

D. All Q37. Sample preparation in IR can be done by

A. Salt plates B. KBr plates C. Nujol mull

D. All Q38. Increase in S character IR causes absorption to move

A. Left side B. Right side C. Const.

D. None Q39. As the atom bonded to C- atom increase in mass, the reduced mass also increases then frequency
A. Also increases B. Decreases C. Const.

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D. Depends on the situation Q40. Simple aliphatic ether can be distinguished from alkane is by
A. C C bond B. C H bond C. Both a and b

D. C O bond Q41. Which one of the following is competitive displacement interaction

A. Warfarin by salicylates B. Methotrexate by sulphonamides C. Both the above

D. None Q42. The cyclic ester in IR appears at ( in cm-1)

A. 1735 1770 B. 1690 1705 C. 1705 1770

D. None Q43. Tetracycline acts by A. Inhibiting protein systhesis B. DNA disruption C. Inhibiting RNA synthesis

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