Pharmaceutical Chemistry 121

Removal Examination
July 14, 2015
Part I. Identification: (40 points)
1. Concerned with the properties and behavior
of inorganic compounds, which include
metals, minerals, and organometallic
compounds.
2. Group 2A elements are also called
____________.
3. Called electron-pair acceptors.
4. The only insoluble group 2A hydroxide.
5. Stabilizer used in Hydrogen Peroxide
Topical Solution, USP
6. Manifestation of borate toxicity
7. Acid used in testing for aromatic amino
acids.
8. Water characterized by its ferruginous taste.
9. Brand name of Lithium Carbonate Tablets,
USP
10. Cation-exchange resin to treat hyperkalemia
resulting from acute kidney failure
11. Best antidote for mercury poisoning
12. Used in antidotal therapy for certain heavy
metal poisoning (particularly for lead)
13. Brand name of the answer in no. 12
14. Use of Soda Lime, NF
15. Trona
is
chemically
_____________
(include water of hydration, if necessary)
16. Endpoint in drying using calcium chloride or
sodium sulfate
17. Medicinal use of sodium nitroprusside
18. Saponifying agent for Medicated Soft Soap,
USP
19. Color of dilute potassium permanganate
solutions
20. Potassium compounds which exists as
irregular, liver brown pieces rapidly changing
to greenish-yellow on exposure to air
21. Prepared by adding zinc sulfate to the
previous number
22. Components of Ammonium Carbonate, NF
(2 points)
23. Components of Aromatic Spirit of Ammonia,
USP (2 points)
24. Chemical composition of Scheeles green
25. Brand name of the orally administered gold
compound for rheumatoid arthritis.
26. Examples of intramuscularly administered
gold compounds (2 points)
27. Components of Toughened Silver Nitrate,
USP (2 points)
28. Medicinal use of 1% silver nitrate solution.
29. Causative agent of the previous number.
30. Challenges the leaching potential of the
interior structure of glass

31. Give 2 examples of pharmaceutical glass

being subjected to the test in the previous
number (2 points)
32. Native hydrated aluminum silicate is
_____________
33. Used as an opacifying agent due to its high
refractive index.
34. Eka-silicon
35. Otherwise known as sugar of lead
Case Analysis: (10 points) Choose from one of the
two and answer the questions accordingly.
Case I. You are being tasked to perform Benedicts
and Fehlings test to check for the presence of
reducing sugars in a commercial juice product.
1) What is the oxidizing agent common to both
reagents? Give 2 other names for this
compound. (3 points)
2) Compare Fehlings and Benedicts reagent
in terms of their sequestering and
alkalinizing agents. (4 points)
3) Give the necessary information: (3 points)
a. Another name for the sequestering
agent in Fehlings test
b. In vivo use of the sequestering
agent in Benedicts test
c. In vitro use of the sequestering
agent in Benedicts test
Case II. A student was accidentally added an acidic
solution to a 10% NaCN solution. Moments later, her
classmate beside her fainted and was rushed to the
hospital.
1) Identify the poison. Give another name for
the poison. (2 points)
2) What antidotes should be given to the
patient? (4 points)
For each antidote, write the
chemical formula and give another
use of the chemical.
3) Fill in the table; write the chemical formula of
the species formed and their other names.
Only fill in cells in which blue precipitates will
be formed. Otherwise, leave the cell blank.
(4 points)
Iron (II)
Ferricyanide
Ferrocyanide

Iron (III)