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quinolone   5 $%  ,
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9. +4 bacterial septicemia !2 meningitis '2$%2 2% !2'!( '! &&
combination 2%) >$?)@(  ! 2%  Pseudomonas aeruginosa, Klebsiella
pneumoniae30-32
92%!
  &'2 Salmonella spp. )'9!: && combination ! 
cefotaxime/ceftriaxone   & ciprofloxacin /8   4-6 /!33
10. Quinolone )  && hypersensitivity type I (anaphylaxis)    2% ! %


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2%
11. 9("/3 febrile neutropenia $% 
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 !!
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19:617-28.
2. Committee on Infectious Diseases. The use of systemic fluoroquinolones.
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3. Centers for Disease Control and Prevention (CDC). Update: Investigation of anthrax associated
with intentional exposure and interim public health guidelines, October 2001. MMWR Morb
Mortal Wkly Rep. 2001;50:889-93.
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anthrax and interim guidelines for exposure management and antimicrobial therapy, October
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Administration approval of ciprofloxacin hydrochloride for management of postexposure
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7. American Academy of Pediatrics. Meningococcal infections. In: Pickering LK, Baker CJ,
Kimberlin DW, Long SS, eds. Red Book 2009: Report of the Committee on Infectious Diseases.
28th ed. Elk Grove Village, IL: American Academy of Pediatrics, 2009:455-63.
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2000;34:347-59.

13. Turnidge J. Pharmacokinetics and pharmacodynamics of fluoroquinolones. Drugs. 1999;58:S2936.


14. Wolfson JS, Hooper DC. Pharmacokinetics of quinolones: newer aspects. Eur J Clin Microbiol
Infect Dis. 1991;10:267-74.
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disposition of sequential intravenous/oral ciprofloxacin in pediatric cystic fibrosis patients with
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antipseudomonal treatment in patients with cystic fibrosis. Pediatr Infect Dis J 1997; 16: 106-11.
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fibrosis: comparative study vs. ceftazidime/tobramycin in the treatment of acute pulmonary
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ciprofloxacin vs. intravenous ceftazidime plus tobramycin in pediatric cystic fibrosis patients:
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moxifloxacin in treatment of pulmonary tuberculosis: a prospective, randomized study.
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at http://narst.dmsc.moph.go.th/ars/box/anti2007.pdf) Accessed on 8 Feb 2011.
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Antimicrob Chemother. 2000;46:653-5.
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2005;5:15-21.
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agents in neutropenic patients with cancer: 2010 Update by the Infectious Diseases Society of
America. Clin Infect Dis. 2011;52:427-31.

 !##$%# Antibiotic and vaccine use in special circumstances


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