MCQ 1/2554

12 Case 120

( 21 24)
1

4.Ferrous supplement

40

Hb 9, Hct
27 %, MCV 67, TIBC 480,
Serum feritin 12

smear microcytic
anemia

1. anemia

a.Iron deficiency
b.Hemolytic anemia
c.Megaloblastic anemia
d.Sickle cell
e.B12 deficiency
2.

a.Folic acid
b.Ferrous sulfate
c.Fresh frozen plasma
d.Vitamin B 12
e.Erythropoietin
3. Ferrous sulfate

a.Thalassemia
b.Thyroxicosis
c.Leucopemia
d.Thrombocytopenia
e.Hemophilia

Elemental Iron
a.Ferrous flumarate
b.Ferrous sulfate
(exsicated)
c.Ferrous glucanate
d.Ferrous sulfate
e.Ferrous citrate
5.Ferrous

a.Folic acid
b.Pyridoxime
c.Ascorbic acid (

)

d.Vitamin B 12
e.Lactose

Ferrous sulfate
-Ferrous sulfate
12.5 g
-Citric acid
0.2
g
-Paraben conc
1
ml
-Syrub add qs 100 ml
6. ( a
b)
a.
b.

c.

10. Ferrous

d.

e.

7.

a.

ferrous sulfate elemental

b.

iron 20%
1

c.

elemental

d.

iron mg
a.0.625 mg
b.625 mg
c.62.5 mg
d.375 mg
e.125 mg
8.

e.

a.EC
b.MC
c.HPMC
d.Polyvinyl alcohol
e.Polyvinyl pyrroridone
9.Ferrous sulfate 100

a.
b.
c.
d.
e.

2
45

1.

1. Clonazepam
2. Diazepam
3. Flunitazepam
4. Lorazepam
5. Temazepam
2.

benzodiazepine
1.
5-HT receptor
2.
Dopamine
receptor
3.
GABA receptor
4.
Glutamate
receptor
5.
Muscarinic
receptor

 3.

1. Barakol
2. Rutinol
3. Aescin
4. Lutin
5. Hesperidium
4. benzodiazepine

1. Anxiety
2. OCD
3. Convulsant
4. Muscle spasm
5. Alcohol withdrawal
5.

benzodiazepine
1.
2. Amnesia anterograde
3.
4.
5.
6.
benzodiazepine
1.
diazepam

therapeutic index

4.

1-2
5. ......
7.
diazepam alcohol
1. .
2.
3. Seizure
4. Hypertensive crisis
5. Respiration depress
8. ......................
9.
A

1. N1 -CH3
2. C7 -NO2
3. C7 -N
4. C3 -OH
5. C2 -CH3

2. Pharmacokinetics


diazepam

3.

10.
diazepam tab 2 mg

1.

. HCTZ

2.

. simvastatin

3.

. enalapril

4.

4.Oligouria

5.

3
80 60 . 160
. atenolol, HCTZ,
simvastatin, enalapril 2

ketoconazole + prednisolone
Lab: K = 7
(), BUN = 62, Scr = 2,
AST & ALT CPK 15,000
1.CrCl = ?
. 15 ml/min
. 20 ml/min
. 25 ml/min
, 30 ml/min
. 35 ml/min
2.?
. hypovolumic induced
. Smoking induced
. alcohol induced
. myoglobin induced
. embolism induced
3.
. prednisolone
. atenolol

.
.
.
. .

5.AST, ALT
. prednisolone
. atenolol
. HCTZ
. simvastatin
. enalapril
6. elyte imbalance

. glucose + insulin
. NSS 3%
. acidic sodium
phosphate solution
. ringers lactase
soluton
. aluminium hydroxide
gel
7.

prednisolone ?

. hypercalemia
. hyperphosphatemia
. hypernatemia
. hyperkalemia
. hypophosphatemia
8.
optimal condition
ketoconazole suspension

. Enalapril table

. prednisolone cream

. simvastatin 20 mg
tablet
. atenolol 50 mg tablet

. pH 1 buteryl
hydroxytoloene conc. 0.3%
. pH 3 buteryl
hydroxytoloene conc. 0.3%
. pH 5 buteryl
hydroxytoloene conc. 0.3%
. pH 7 buteryl
hydroxytoloene conc. 0.1%
. pH 9 buteryl
hydroxytoloene conc. 0.3%
9.
ketoconazole

. oxidation
. hydrolysis
. photolysis
. oxidation
photolysis
. hydrolysis
photolysis
10.

. ketoconazole
shampoo

4 70
81 150

2
7


penicillin sulfonamide

2
LAB: FBS 180 mg%,
HbA1C 9%
MED:
Acarbose 50
mg tid
Salbutamol inhale
MDI
Atenolol mg 1x2
pc
ASA 81 mg 1x1 pc
Prednisolone 5 mg
2x2 pc
1.

1) flatulence
2) hypoglycemia

3) ..
4)
5)
2.


1) glipizide
2) glibenclamide
3) metformin
4) insulin.
5) insulin
3.
metformin
1) lactic acidosis
2)
3)
4)

5)
4.

1) ACEIs
2) alpha-blockers
3) B-blockers
4) loop diuretics
5) Thiazides
5.
hypoglycemia
1) salbutamol inhale
2) ASA
3) acarbose
4) atenolol
5) prednisolone
6. 2
amorphous

1)
2)
3)
4)

5)

7. amorphous

1) Differential Scanning
Calorimetry
2) High Performance
Liquid Chromatography
3) Mass Spectrometry
4) Polarization
5) Scanning Electron
Microscope
5 70


wheezing

15
40 6
FEV1 = 0.8, FVC = 1.5 L

COPD
Rx Salbutamol 2 puff
prn # 1
Acetylcysteine 1
tid
# 120
1.
COPD

. wheezing

. FEV1/FVC

< 12%
.FEV1

> 0.7
2.
salbutamol
.
.
.
.
.

3.
salbutamol
.
Enantiomer
.
Diasteriomer
.
.

.Agonist
antagonist
4. Salbutamol

7.
seratide accuhalor
.
. propellent
. 1 dose

. meter dose valve

8.
seratide accuhalor

. 65
.
.
.
.
6 15

15 kg

2
1

1.

.Salmonella
.Entamoeba histolytica
.Acinobactor spp.
.Shigella
.Rotavirus
2.

.Caolin-pectin
.Diphenoxylate
.Activated charcoal
.Oral rehydrate salt
.Dioctasmectite
3.

Diphenoxylate
.Hypokalemia
.Hyperglycemia
.Thrombocytopenia
.Drowsiness
.Tinnitus
4. 1

Sodium chloride
2.9 g
Trisodium citrate
dehydrate
2.9 g
Potassium chloride
1.5 g
Glucose anhydrous
13.5 g
1

Sodium
(MW sodium
chloride = 58, Sodium citrate
dehydrate = 294.1,
Potassium chloride = 74.55)
.60 mEq/Litres
.70 mEq/Litres
.80 mEq/Litres
.90 mEq/Litres
.100 mEq/Litres
5. Glucose anhydrous
Glucose Glucose
(Glucose anhydrous 1
g equivalent Glucose 1.1
g)
.12.xx g
.14.85 g
6.
.

. 24

7.

.
.
.
8.Cotrimoxazole

.Pancreatitis

160 mg OD

.Heart failure

simvastatin 40 mg OD

.G-6PD deficiency

3 LDL 90

.Epilepsy

mg/dl TG 140 mg/dl

.Diabetes mellitus

1.

9.
cotrimoxazole
24 mg/kg bid x 3

1. simvastatin
80 mg

SMX/TMP 200/40 mg 1

2. fibrate

3.

. 2

4. simvastatin

. 2

5. ezetimibe

. 3

simvastatin

. 2

2.

.
3

Gemfibrozil

7
60 65 BMI 26

TC 250 mg/dl (<200)

TG 190 mg/dl (<200)
LDL 170 mg/dl (< 100)
HDL 42 mg/dl (> 50)
ALT 35 (< 40)
AST
30 (< 40)
BP 136/85 mmHg
Scr 0.8 mg/dl

5
Valsartan

(Rhabdomyolysis)

1.Chlorestyramine
2.Ezetimibe
3.Cholostipol
4.Fish oil
5.Fenofibrate
3. gemfibrozil
monitor
1.BUN
2.serum transaminase
3.serum albumin
4.5.Scr
4. Pleiotropic Effect
Statin

1.

1.

2.
3.
atherosclerotic plaques
4. glucose tolerance
5.
atherosclerotic plaques

MI
Atorvastatin
Simvastatin

3. lactone ring

5. complex

8.
simvastatin 10 mg

Incident
1,114
2,520

1. MI

2.Atorvastatin MI
Simvastatin
3.Simvastatin
MI 100
4.Simvastatin MI
Atorvastatin
7. simvastatin

2. prodrug

4. lactone ring

5.

Atorvastatin
Simvastatin

Simvastain
10 mg
Lactose monohydrate
30
mg
Microcrystalline cellulose
Ascorbic acid, Colloidal
silicon dioxide
1. Direct compression
2. Dry granule via slug
3. Dry granule via
chilo
4. Wet granuletion
9.
(Glidant)
1.Ascorbic acid
(Antioxidant)
2.Colloidal silicon
dioxide
3.Microcrystalline
cellulose (Disintegrant)
4.Lactose monohydrate
(Diluent)

10. Simvastatin

3.omeprazole

1.Ischemic stroke
2.Hemorrhagic stroke
3. Renal failure
4.Arthrosclerosis
5.Peripheral artery
disease
8

clopidogrel toxic

50

mefenamic (500 mg)
13 /

Omeprazole 20 mg
1x2
Al(OH)3 + Mg(OH)2 1
tbsp
3
omeprazole
clopidogrel

metabolite
4.omeprazole
clopidogrel
5.omeprazole
clopidogrel

4 omeprazole

1.Erythromycin
2.Ketoconazole
3.Diazepam
4.Warfarin
5.Escitalopam
7

omeprazole capsule

1.

2.

3.

1.omeprazole

4.

clopidogrel

5.

2.clopidogrel
omeprazole

8 Aluminium +
Magnesium

1.

2.

3.

4.

5.

. Varicella
. Rubella
. Measles
2.

.
.
.
.
.
3.

. Paracetamol

omeprazole

. Ibuprofen

H+/K+ ATPase

. Amitriptyline

Acyclovir
1.

. Herpes simplex
. Herpes zoster

4. emulsion

emulsifier
. Stearic acid
. Cetyl alcohol
. Potassium hydroxide
. Potassium stearate
5

Acyclovir
.

. Metoprolol

. Lisinopril
. ASA

10

. Simvastatin

57 Ishemic MI

. Isosorbide dinitrate

30

ISDN 1

2
HT, DM, DLP

6. Metoprolol

Acute MI
1.
MI
. CT scan
. Chest X-ray
. EKG
2. Lab

. 10

7.
metoprolol

. Serum Creatinine
. Serum Transaminase
. Troponin & CK-MB
3.

. ASA 325 mg
. Simvastatin 80 mg
. Warfarin 5 mg
. Metoprolol
. Streptokinase
4. cGMP

metoprolol
(
)
1. Propranolol

2. Pindolol

Enteric coated
tablet
11 Case
40

3. Atenolol

kg 160 cm

Cyclophosphamide 100
mg/m2
day 1-14
Methotrexate
40
mg/m2
day 1, 8
Fluorouracil
600
mg/m2
day 1, 8
1. mosteller

4.

5.

solution Fluorouracil

.600
.700
.800

8.
isosorbide dinitrate SL

1.
2.

3.

4. hepatic
first pass metabolism
5.

9. ASA

.900
.1000
2. MTX


.Alkylating agent
. enzyme of
dihydrofolate reductase
. enzyme of
thymyldilate syntase
.deporalizing of
microtubule
.antagonist of estrogen
receptor
3. ADR MTX

4. cyclophosphamide

DV

solution 1 cycle

cyclophosphamide 50 mg/
1 25 mg

mL (

agent

BSA
)
Cyclophosphamide
100 mg/m2 day 1-14
1400 mg/cycle
1400/25
= 56
50 mg
15 mL 1400 mg
420 mL
5.
MTX 1 g

50 mg/mL
( Displacement Value
= 0.05 mL/100 mg)
50 mg
1 mL 1000
mg 20 mL Displacement
value 100 mg
0.05 mL 1000 mg
0.5 mL
20-0.5 =
19.5 mL

6. Cyclophosphamide
alkylating
.Cytarabine
.Vincristine
.Cisplatin
.Paclitaxel
.Tamoxifen
7. 5-FU
(Antitumor effect)
leucoverin
9.
stomatitis

5-FU
1. Sucralfate
2. Mesna
3. Leucoverin
4. Prednisolone
5. Hyaluronidase
10.

.
.
.

.
.

. Acyclovir

. Tenofovir

.
Acyclovir
cream

12





Clobetasol cream
1.

4.

. Tinea versicolor
. Contact dermatitis

. Sebolic dermatitis
. Psoriasis
2.

. Infection
. Allergic reaction
. Autoimmune disease
. Sebolic inflammation
3.
.
Acyclovir
7

13
40
Clotrimox
Erythema multiform


RA
1.

1)Diclofenac
2)Glucosamine
3)Prednisolone
4)Auro ()

2.

6. Prednisolone 5 mg

10

1)

1)Cyclosporine
2)Azathiopine
3)Prednisolone
4)Celebrex
3.
O

2)
3)
4)
5)
7.

N
o

prednisolone 5 mg
(

NO2

1)
Spectrofluorometer
2)
3)Metabolite para
carboxylation
4) Sulfonylurea
5)
Hydrolysis
4.

1)Ibuprofen
2)Celecoxib
3)Glucosamine
4)Sulfasalazine
5)Metrotexate
5. steroid

1)Hydrocortisone
2)Prednisolone
3)Cortisone
4)Dexamethasone

)
1)Dissolution
2)Content uniformity
3)Identify
4)Assay
5)Mass uniformity
8.
1)Glucosamine
2)MTX
3)Celecoxib
4)Sulfasalazine
14 Thyroid
disease
1.

1.
2.
3.
4.
2.

3.
1.

2.I131

3.Thyroxidosis
Grave,s
4.

4. Carbimazole

7. Lugols solution
( KI I2)

1. KI

I2

2. I2

KI

3. KI I2

8.

9. Carbimazole

5.Adjuvant drug

10.

1.Iodine
2.Perglaride
3.vit B 1-6-12
4.Pergabide
5.Propranolol
6.

27 ..

1.I
2.Salbutamol
3.Lugol,s solution
4.Dexamethasone
5.CaCo3
131

35

53
15
35

penicillin urticaria
1.
1.S. pyogenes

2.S. aurese
3.P.aeruginosa
4.A. baumannii
5.C. difficile
2.

1.Dextromethorphan
2.Brompheniramine
3..
4.Tipolidine+pseudoeph
edrine
5.Guaifenesine
3.
1.Amoxycillin
2.Clarithromycin
3.Bactrim
4.Levofloxacin
5.Clindamycin
4. Antibiotic

1.Amoxycillin
2.Clindamycin 50s
ribosome
3.Bactrim
4.Levofloxacin
5.Clindamycin
5.

1.Amoxycillin
2.Clarithromycin
3.Bactrim
4.Levofloxacin
5.Clindamycin
Rx
Glycyrrhiza fluid extract 12
ml

Antimony potassium tartate

24 mg
Camphor opium tincture 12
ml
Glycerine 12 ml
Water qs 100 ml
...
6.

1. Camphor

opium tincture
2. Camphor opium

tincture

3.
Antimony potassium
tartate
4. Antimony
potassium tartate
Glycyrrhiza fluid extract
5. Antimony
potassium tartate
Camphor opium tincture
7.

1. Camphor opium
tincture
emulcent..

TT_TT
2. Antimony potassium
tartate artificial
sweetener
3. Glycerine
Antimony potassium tartate

4. Glycyrrhiza fluid
extract expectorant
5. Glycyrrhiza fluid
extract bitter tonic
16
24

(Standard treatment)
4.
Itraconazole

( )

(disintegrant gent)
.lactose

1.
.Trichophyton spp.
.Cryptococcus spp.
.Malazzesia furfur
.Pneumocystis carinii
Pneumonia
.Staphylococcus
aureus
2.
.whitefields ointment
.clotrimazole cream
.ciclopirox olamine
.selenium sulfide
3.


.2
.4
.2
.6
.8

.colloid silicon dioxide

.sodium starch
glycolate
.magnesium state
.polyvinylpyrrolidone
5.
Itraconazole pulse therapy
.
.

. compliance

. pulse
therapy

.
6. Itraconazole tablet

.griseofalvin
.terbenafine

.tolnaftate

.fluconazole

10.

.miconazole

. cotrimazole
terbenafine
.

2009

7.

2019
. %LA = 87%

.oleaginous bases
.absorption bases
.w/o emulsion bases
.o/w emulsion bases
.water soluble bases
8.

.ointment
.lacquer
.water spray
.cream
.alcohol spray

17
20
15

1.
.

9.

amphotericin B
. CYP 450
.
ergosterol
. ergosterol
cell membrane
. RNA
polymerase
.

. (
)
.
.

.
2.

. aloe vera gel

. erythromycin

. diclofenac gel

6.

. steroid

3.

. Escherichia coli.
. Bacteriodes fragilis.
. Staphylococcus
aureus.
. Streptococcus
pneumoniae.
. Pseudomonas
aeruginosa.
4.

. 70% ethanol

. silver sulfadiazine
cream
. mucoprolin cream
. gentamicin cream
. mercury cream
. fusidic acid cream
7. povidoneiodine

. acetyl alcohol
. carbomer
. acacia
. dimethicone
. simethicone

. 70% isopropyl alcohol

. normal saline
solution
. povidone-iodine
solution
. hexachlorophene

8.
erythromycin
.

5.

. amoxyciilin
. cotrimoxazole
. dicloxacillin

.
.
.

.
.

18 22
2

E
cream base
Rx
stearic acid
100 g
lanolin
20 g
cetyl alcohol
xg
mineral oil light
50 g
potassium hydroxide
5g
propylene glycol
50 g
purified water to make
1,000 g
9.
emulsifier
. stearic acid
. lanolin
. cetyl alcohol
. potassium hydroxide
. potassium stearate
potassium stearate
10.

2-3

1.
1.Blephetis
2.Hordeolum
3.Glaucoma
4.Bacterial
conjunctivitis
5.Allergic conjunctivitis
2. contact
lens
1. contact lens

2. contact lens


3.
contact
lens 1-2
4.
contact lens
5. contact lens

3. ophthalmic
decongestant

1.Phenylephrine
2.Oxymetazoline
3.Nephazoline
4.Antazolin
5.Tetrahydrozoline
4.

1.Escherichia coli
2.Staphylococcus
aureus
3.Acinetobacter spp.
4.Neisseria gonorrhoeae
5.Buekholderia
pseudomalle
5.
Neomycin sulfate, Polymycin
B sulphate, NaCl,
Benzakonium chloride,
Hypromellos,
Disodiumedetate
Hypromellos
1.
Neomycin
2.

3.

4.
5.

6.
Dexamethasone eye drop

1.

2.

3.

4.

5.

19
60

2 day PTA

1 day PTA

Benign
prostatic hyperplasia
Hypertension

Prazocin 2mg OD PC

1.

a.Complication cystitis

b.Uncomplication
cystitis
c.Complication acute
pyelonephritis
d.Uncomplication acute
pyelonephritis
e.Complication Urithitis
2.Lab

a.Urine gram stain

b.Urine culture
c.Renal function test
d.Complate blood count
e.VRDL
3.

a.pH
b. dielectric
constant
c.Micell
d.Cosolvent
e.Complexation
6.Norfloxacin

a.Norfloxacin BID 3 days

b.Norfloxacin BID 5

days
c.Ciprofloxacin BID 3
days
d.Ciprofloxacin BID 14
days
e.Co-trimoxazole BID 3
days
4.

a.BPH
b.Male
c.Hypertension
d.On Prazocin
e.
5.Norfloxacin

cyclodextran (
cyclodextran
Norfloxacin )

a.

b.

c.

d.

e.
7.

a.Ciprofloxacin
Theophylline
b.Antacid
Ketoconazole
c.Azithromycin
Phenytoin
d.Azithromycin
Digoxin
e.Antacid
Ciprofloxacin
8.Ciprofloxacin

Ciprofloxacin

.Raynaud

3. IV

Ciprofloxacin )

dihydroergotamine
IV
dihydroergotamine
.Rifam

a.
b.
c.
d.
e.

F
OH
=O
Cyclopropyl
NH-

.Ritonavir
.Roxithromycin
.loratadine
4. caffeine ergot

20

1.

.Ibuprofen
.sumatriptan
.tramadol
IV
dihydroergotamine
2. IV dihydroergotamine

.asthma
.vasculitis
.pancreatitis
.Reyes syndrome

.
5.
3-4

.sumatriptan
.naproxen
.propanolol
.cinnarizine
.valproic acid
6.
ergot

.cytotoxic
.mutagenic
.teratogenic
.cytotoxic
.spasmolytic

7.

( )

6 ..
.suppo

()

.effervescent tablet

.inhale

1. (choice

.IM

8.9. ergotamine

T^T)
a

bioavailability

parameter

.Half life

b 20

.Vd

.AUC

8.00 .

10. ergotamine

.T-test unpair

2.

.T-test pair

a 48
b 24
c 72
d 12
3. 2

.F-test
.Mann withney u test
21
( )
15 28
5 ..
4

(!

8.00 . 15
.. 53
53
53

a 12.00 . 15 ..
b 20.00 . 15 ..
c 8.00 . 16 .. 53

53

d 20.00 . 16 ..

e 8.00 . 17 .. 53
4. Progestogen only pill

a Lynestrenol
b Drospirenone
c Norethisterone
d Levonorgestrel
e Gestodene
5. Drug interaction

a Rifampicin
6.

Progesterone
a

b
c
d
e
7.


hormone

website

d


OH

O
e

8.

b

c

d
e
9.

a Tight container
b Single unit container
c Multiple unit container
d Tamper resistance
packing
e Light resistance
container

10. (

d B estogen

e A estrogen
CH3

B
O
a A androgenic
b B androgenic
c A androgenic
B

Case!!!!!
???