Sucralfate Suspension enema 4% w/v

Bill of Materials
Sl.no Material Name specificatio Qty/100L
n (kg)
1 Cremophor RH 40) USP 1.00
2 Xanthan gum(clear) IP 0.500
3 Water IP 40.00
4 Propylene glycol IP 20.00
5 Activated dimethicone IP 0.100
6 Sucralfate USP 4.00
7 Sodium benzoate IP 0.200
8 Water IP 40.00

Manufacturing Directions
1. Add a blend of Cremophor RH 40) and Xanthan gum to Water slowly, agitating
with maximum available shear until a smooth and uniform mix is obtained.
2. Mix together Propylene glycol, Activated dimethicone to Sucralfate in another
vessel until uniform
and then add to the above mix and agitate until uniform.
3. Add item Sodium benzoate and mix until uniform.

4.Make up to volume with the remaining quantity of water.