1

INTRODUCTORY HAEMATOLOGY AND IMMUNOLOGY PRACTICE

MCQ AND SAQ (put online)

HAEMATOLOGY MULTIPLE CHOICE QUESTIONS

Circle the most correct answer. Each question has only ONE correct answer.

1. Plasma:

(A) Is the fluid portion of blood following defibrination

(B) Contains more protein than serum
(C) Comprises 40% of blood by volume
(D) Contains no coagulation factors
(E) Contains more than 1000 plasma proteins

2. Normal adult haemoglobin (HbA):

(A) has a molecular weight of 36,000 daltons

(B) consists of two globin chains and two heme groups
(C) contains two alpha and two gamma globin chains
(D) contains two alpha and two beta globin chains
(E) contains four beta chains and one heme group

4. Iron deficiency anaemia is:

(A) A macrocytic anaemia

(B) The least common anaemia world-wide
(C) Always caused by dietary insufficiency
(D) Characterised by a low MCV
(E) Common in adult males

5. Basophil granules contain:

(A) Histamine
(B) Peroxidase
(C) 5-hydroxy tryptamine
(D) All of the above
(E) None of the above

6. Monocytosis is commonly observed in all of the following EXCEPT:

(A) Rheumatoid arthritis

(B) Tuberculosis
(C) Syphilis
(D) Hayfever
(E) Hodgkins disease
 2

7. Schistocytes are:

(A) Abnormal granules in neutrophils

(B) Associated with Pelger-Huet anomaly
(C) Present in anaemias due to dietary insufficiency
(D) Also known as target cells
(E) Fragmented erythrocytes

8. Mast cells:

(A) Have a diameter of approximately 20-25m

(B) Are mediators of vasoconstriction
(C) Have an important role in hypersensitivity
(D) Reside in tissues other than blood
(E) All of the above

9. Kuppfer cells are macrophages that are present in the:

(A) Lung
(B) Liver
(C) Skin
(D) Brain
(E) Bone marrow
 3

HAEMATOLOGY SHORT ANSWER QUESTIONS

1. Define the following:
(a) Serum

(b) Reference range

(c) Mean cell volume

(d) Erythropoiesis

(e) Polychromasia
 4

2. Briefly describe the major differences between:

MCH and MCHC

_______________________________________________________________
_______________________________________________________________

HbA and HbS

_______________________________________________________________
_______________________________________________________________

Proerythroblast and reticulocyte

_______________________________________________________________
______________________________________________________________

3. List four examples of poikilocytosis and give a brief description of each

(a) ________________________________________________________
_______________________________________________________________
_________________________________________________
_______________________________________________________________

(b) ________________________________________________________
_______________________________________________________________
_________________________________________________
_______________________________________________________________

) ________________________________________________________
_______________________________________________________________
_________________________________________________
_______________________________________________________________

(d) ________________________________________________________
_______________________________________________________________
_________________________________________________
_______________________________________________________________
_________________________________________________