Formation of a nucleotide

Three compounds are needed HO

O
OH

to make a nucleotide deoxyribose

OH

They combine through

two condensation NH2

reactions (condensation N
N a base
means ‘splitting out’
water, H2O) NH
(this one is adenine)
N

Click to follow the

O
formation of the and
nucleotide from these HO P OH
phosphoric acid
three compounds OH
 NH2 NH2

N N
N N
a base
HO N N NH N
O

H2O
OH

a condensation reaction

HO OH
O
And now a phosphate group is added by reaction with phosphoric
acid – click to see the reaction deoxyribose

OH
 NH2

N
N
O

HO P OH HO N N
O
OH

H2O
OH

NH2

a condensation reaction
N
N
O

HO P O N N
O
OH
Click for a larger
OH
H2O
diagram of the
H2O
nucleotide
 The nucleotide formed from:
deoxyribose, adeninine and phosphoric acid
is

NH2

N
N
O

HO P O N N
O
OH

OH

This is called AMP

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