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PATHOPHYSIOLOGY OF UTERINE CANCER

Predisposing Factors:
Precipitating Factors: -Age: over 50 y/o
-Race: Black Americans
Hormone Replacement Therapy Estrogen
-Genetic
-Obesity: increase ESTROGEN -Disease: Endometrial Hyperplasia. Colorectal
-Lifestyle: Exposure to Carcinogens menstruation
-Sexual Activity: nulliparity -Physiologic changes: Early menstruation, Late
menopausal stage, amenorrhea

Excessive Increase estrogen

Suppress LH and FSH

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