1. Use the Windows key + R keyboard shortcut to open the Run command.

2. Type regedit, and click OK to open the registry.

3. Browse the following path:

HKEY_LOCAL_MACHINE\Software\Microsoft\Windows\CurrentVe
rsion\Policies\ Explorer

4. Right-click on the right side, select New, and click on DWORD (32-bit)
Value.

5. Name the new DWORD NoDrives and press Enter.

6. Double-click the newly created DWORD.
7. Under "Base," select the Decimal option.
8. On "Value data" enter the decimal number that represents the drive letter
you want to hide. For the purpose of this guide, we'll be using value 16,
because we're hiding the E: drive.
 If you want to hide multiple drives, you'll need to add the decimal numbers.
For example, if you're trying to hide drive D: and E:, you'll need to add 8 +
16, which means that the value you need to enter is 24.

Quick Tip: You can use these decimal numbers as reference to hide
specific drives: A: 1, B: 2, C: 4, D: 8, E: 16, F: 32, G: 64, H: 128, I: 256, J:
512, K: 1024, L: 2048, M: 4096, N: 8192, O: 16384, P: 32768, Q: 65536, R:
131072, S: 262144, T: 524288, U: 1048576, V: 2097152, W: 4194304, X:
8388608, Y: 16777216, Z: 33554432, ALL: 67108863.

9. Click OK.
10. Close the Registry.
11. Restart your computer to apply the new changes.