4008 H / 4008 S

Hemodialysis Machine

Technical Manual

Supplemental Instructions for the OCM Option

Part no.: M32 514 1

Fresenius Medical Care

Table of Contents

Section Page

1 Description of errors .................................................................................................... 1-1

1.1 Display messages ........................................................................................................... 1-3
1.2 Description of errors ....................................................................................................... 1-5

3 Adjustment instructions ............................................................................................... 3-1

3.1 Measuring equipment ..................................................................................................... 3-3
3.2 Flow diagram .................................................................................................................. 3-4
3.3 Calibration mode ............................................................................................................. 3-8

4 Calibration program ...................................................................................................... 4-1

6 Setup menu ................................................................................................................... 6-1

6.1 Overview ......................................................................................................................... 6-1
6.2 Main menu 4008 H/S ...................................................................................................... 6-2

8 Circuit diagrams ............................................................................................................ 8-1

8.1 Circuit diagrams and component layout LP 632, CPU 2 ............................................... 8-3
8.2 Circuit diagrams and component layout LP 633-5, Input board .................................... 8-19

Fresenius Medical Care 4008 OCM Supplement 2/10.01 (TM) 0-1

0-2 Fresenius Medical Care 4008 OCM Supplement 2/10.01 (TM)
Table of Contents 1 Description of Errors

Section Page

1.1 Display messages ......................................................................................................... 1-3

1.1.1 Informational messages .................................................................................................. 1-3
1.1.2 Warnings ......................................................................................................................... 1-4

1.2 Description of errors ..................................................................................................... 1-5

Fresenius Medical Care 4008 OCM Supplement 2/10.01 (TM) 1-1

1-2 Fresenius Medical Care 4008 OCM Supplement 2/10.01 (TM)
1.1 Displaymeldungen

1.1.1 Informative Meldungen

Clear.: XXXml/min Shows the last measured clearance value. Displayed for
1 minute after a successful measurement.

Plasma-Na: XXXmmol/l Shows the plasma sodium concentration of the last single
measurement for 1 minute.

Kt/V: X.XX Shows the current Kt/V. Displayed for 1 minute when the UF
goal has been reached or if the OD senses clear fluid.

Kt: XX.Xl Displayed instead of “Kt/V:X.XX” if no valid value for Vurea is

available. Shows the current value of Kt. Displayed for
1 minute when the UF goal has been achieved or if the OD
senses clear fluid.

Kt/V: Not available There are no Kt/V data available as the calculation of Kt/V was
aborted. Displayed for 1 minute when the UF goal has been
achieved or if the OD senses clear fluid.

Enter V(urea)? This message is displayed at the start of a dialysis treatment

provided the operator has not already entered the V urea on the
screen. This message will be displayed when the OCM is
switched on manually by the operator or after the optical de-
tector has sensed blood, provided “OCM measurement ON”
was preselected in the Setup. This message prompts the ope-
rator to enter the patient’s volume of urea distribution. It will
only be displayed if the Vurea has not yet been entered. If the Vu-
rea
has been changed during the OCM measurement, the Kt/V
will be recalculated provided it is already available. This mes-
sage will be cleared by pressing the Start/Reset key.

HDF/HF < > OCM An OCM and an HDF or HF treatment procedure cannot be
performed simultaneously. Displayed once if OCM is selected
while HDF/HF is active. If HDF/HF is selected while OCM is al-
ready active, the OCM will be aborted and the message “OCM
off” will be displayed. The OCM can, however, be reselected
after HDF/HF has been switched off.

SN < > OCM The OCM cannot be started as a Single Needle treatment (SN
or SN click-clack) has been selected.

Profile< > OCM An OCM cannot be started in conjunction with a Na-/UF profile
1, 5 or 6 and a treatment time of less than 180 minutes. Dis-
played when the OCM is switched on and/or when selecting a
profile.

Fresenius Medical Care 4008 OCM Supplement 2/10.01 (TM) 1-3

 OCM tech. deact./X The OCM cannot be started as the CD cells or the temperature
sensors are not properly calibrated or have been manually de-
activated when operating the machine. Also displayed when
the integral relationship of the adjustment measurement is out-
side the limits. Displayed when the OCM is activated manually
or when the OD senses dark fluid if the default setting for the
OCM is set to active.
Inform the service technician of the error code (X).

OCM off/X The OCM was aborted due to a malfunction and will be deacti-
vated until the end of the treatment.
Inform the service technician of the error code (X).

OCM adjust Displays during an OCM adjustment.

OCM adjust OK Displays after successful completion of an OCM adjustment.

OCM adjust cancelled The OCM adjustment was not successfully completed and will
be repeated after the next treatment.

OCM adjust intended Displays when the optical detector senses dark fluid and if an
adjustment measurement is required on completion of the
treatment in progress.

Input value too low The operator has attempted to enter a value for an OCM para-
meter that is below the minimum limit.

Input value too high The operator has attempted to enter a value for an OCM para-
meter that is above the maximum limit.

1.1.2 Warnings

Kt/V too low Displays if the prescribed Kt/V cannot be reached at the end of
the treatment with the current Kt/V.

1-4 Fresenius Medical Care 4008 OCM Supplement 2/10.01 (TM)

1.2 Description of errors

Error message displayed Description

OCM OFF The OCM option will be deactivated until the machine is
switched off.
– Power failure with battery backup
– CPU II error

OCM OFF/2 The OCM option will be deactivated until the machine is
switched off.
One of the CD cells has measured a value below 11.5 mS/cm
during more than 3 consecutive OCM measurements.
– Check CD cells for proper connection
– P.C.B. LP 633-5 defective

OCM OFF/3 The OCM option will be deactivated until the machine is
switched off.
– System error

OCM OFF/5 The OCM option will be deactivated until the machine is
switched off.
A downward pulse occurs although an upward pulse was re-
quested.
– Check the bibag/concentrate delivery
– Check the concentrate pumps / mixing system
– Air in the dialysate

OCM OFF/6 The OCM option will be deactivated until the machine is
switched off.
– System error

OCM OFF/7 The OCM option will be deactivated until the machine is
switched off.
Implausibility of the ratio of blood flow to clearance or no appa-
rent change on the CD cell during more than three consecutive
measurements.
– Poor terminal connection of the CD cell

Fresenius Medical Care 4008 OCM Supplement 2/10.01 (TM) 1-5

 Error message displayed Description

OCM tech. deact./1 The OCM option is decalibrated and can only be reactivated
after a successful pulse calibration.
Deviation between the 8-bit and the 12-bit CD value of the pre-
cell > 0.5 ms/cm for > 20 s.
– Disinfection
– Check OCM calibration and calibrate, if necessary

OCM tech. deact./4 The OCM option is decalibrated and can only be reactivated
after a successful pulse calibration.
Three cyclic pressure holding tests (CPHT) showed a deviation
of > 0.5 ms/cm between CD cell 7 and CD cell 110 for > 4.5 s.
– Disinfection
– Check OCM calibration and calibrate, if necessary

OCM tech. deact./7 The OCM option is decalibrated and can only be reactivated
after a successful pulse calibration.
More than 5 consecutive measurements showed a clearance of
more than 1.3 times the blood flow or below zero.
– Check the CD cells for poor terminal connection.
– Disinfect, if necessary
– Check the calibration

OCM tech. deact./8 The OCM option is decalibrated and can only be reactivated
after a successful pulse calibration.
Zero pulse measurement failure or time of maximum pulse be-
tween pre- and post-CD cell > 13 s.
– Check the hydraulic for proper flow
– Check OCM calibration and calibrate, if necessary

OCM tech. deact./9 The OCM option is decalibrated and can only be reactivated
after a successful pulse calibration.
The correction factor of the zero pulse measurement for upward
or downward pulses is outside the acceptable range of 0.8 to
1.2.
– Perform a disinfection
– Check OCM calibration and calibrate, if necessary

1-6 Fresenius Medical Care 4008 OCM Supplement 2/10.01 (TM)

Table of Contents 3 Adjustment instructions

Section Page

3.1 Measuring equipment ................................................................................................... 3-3

3.2 Flow diagram ................................................................................................................. 3-4

3.2.1 Flow diagram 4008 H with OCM ..................................................................................... 3-4
3.2.2 Flow diagram 4008 S with OCM ..................................................................................... 3-6

3.3 Calibration mode ........................................................................................................... 3-8

3.3.1 Basic conditions .............................................................................................................. 3-8
3.3.2 Display messages (4008 H/S) ........................................................................................ 3-8

Fresenius Medical Care 4008 OCM Supplement 2/10.01 (TM) 3-1

3-2 Fresenius Medical Care 4008 OCM Supplement 2/10.01 (TM)
3.1 Measuring equipment

Caution
The accuracy of the measuring equipment used during the calibration procedure
is decisive for the accuracy of the OCM measurement.
The measuring equipment used for the calibration of the conductivity must have
an accuracy of 0.05 mS/cm within a temperature range of 35 °C – 39 °C.
We recommend to use the UMED universal measuring device which is available
from Fresenius (part no. M32 403 1).

UMED Service Case

Part number M32 403 1

Fresenius Medical Care 4008 OCM Supplement 2/10.01 (TM) 3-3

3.2 Flow diagram

3.2.1 Flow diagram 4008 H with OCM

3-4 Fresenius Medical Care 4008 OCM Supplement 2/10.01 (TM)

Legend

2 Temperature sensor 95 Bicarbonate suction tube

3 Temperature sensor 97 Air separation pump
4 Temperature sensor 99 Rinse valve
5 Float switch 100 Rinse valve
6 Level sensor 102 Central concentrate delivery valve
7 Conductivity cell 104 Central bicarbonate delivery valve
8 Blood leak detector 109 Temperature sensor
9 Pressure transducer 110 Conductivity cell
10 Reed contact, concentrate 111 Hydrophobic filter
12 Reed contact, bicarbonate 112 Vent valve
21 Flow pump 114 Dialysate filter
22 UF pump 115 Sensor Disinfection valve
23 Concentrate pump 116 Sampling valve
24 Dialyzer valve 1 117 Check valve / concentrate
24b Dialyzer valve 2 118 Check valve / bicarbonate
25 Bicarbonate pump 119 Filter / concentrate
26 Bypass valve 120 Filter / bicarbonate
29 Degassing pump 121 Central concentrate delivery connector
30 Outlet valve 122 Central bicarbonate delivery connector
31 Balancing chamber valve 1 123 Pressure switch for V102
32 Balancing chamber valve 2 124 Pressure switch for V104
33 Balancing chamber valve 3 130 biBag drain valve
34 Balancing chamber valve 4 132 biBag conductivity cell
35 Balancing chamber valve 5 133 biBag temperature sensor
36 Balancing chamber valve 6 134 biBag pressure transducer
37 Balancing chamber valve 7 136 biBag connector
38 Balancing chamber valve 8 137 biBag micro-switch 1
39 Negative pressure valve 138 biBag micro-switch 2
41 Water inlet valve 148 Filter / rinse valve V100
43 Fill valve 149 Filter / rinse valve V99
54 Heater rod 150 Filter / fill valve
61 Pressure reducing valve 151 Orifice
63 Water inlet filter 181 Temperature compensation plate 2
65 Loading pressure valve 182 Pressure transducer 2
66 Heater block 183 Test valve
66a Water inflow chamber 184 Filter / test valve
66b Heater rod chamber 185 Compressor
66c Float chamber 188 Evacuation valve
68 Balancing chamber 189 Retentate valve
71 Filter / concentrate 190 Online filter
72 Filter / bicarbonate 191 Online valve 3
73 Filter / dialysate ext. 192 Online valve 2
74 Filter / UF 193 Online valve 1
75 External flow indicator 194 Rinse port
76 Filter / fill valve 195 Substituate port
77 Heat exchanger 201 Air separator / concentrate
78 Relief valve 202 Level sensor / concentrate
84 Disinfectant valve 203 Air separator / bicarbonate
85 Disinfectant connector 204 Level sensor / bicarbonate
86 Recirculation valve 205 Mixing point / concentrate / bicarbonate
87 Drain valve 206 Buffer volume chamber
88 Multifunction block 210 Filter
88a Degassing chamber
88b Secondary air separator
88c Primary air separator Hydraulics measuring points:
89 Degassing orifice
90a Rinse chamber / concentrate A Reduced water inlet pressure
90b Rinse chamber / bicarbonate B Balancing chamber loading pressure
91 Rinse valve C Flow pump pressure
92 Vent valve D Degassing pump pressure
94 Concentrate suction tube

Fresenius Medical Care 4008 OCM Supplement 2/10.01 (TM) 3-5

3.2.2 Flow diagram 4008 S with OCM

3-6 Fresenius Medical Care 4008 OCM Supplement 2/10.01 (TM)

Legende

2 Temperature sensor 95 Bicarbonate suction tube

3 Temperature sensor 97 Air separation pump
4 Temperature sensor 99 Rinse valve
5 Float switch 100 Rinse valve
6 Level sensor 102 Central concentrate delivery valve
7 Conductivity cell 104 Central bicarbonate delivery valve
8 Blood leak detector 109 Temperature sensor
9 Pressure transducer 110 Conductivity cell
10 Reed contact, concentrate 111 Hydrophobic filter
12 Reed contact, bicarbonate 112 Vent valve
21 Flow pump 114 Dialysate filter
22 UF pump 115 Sensor Disinfection valve
23 Concentrate pump 116 Sampling valve
24 Dialyzer valve 1 117 Check valve / concentrate
24b Dialyzer valve 2 118 Check valve / bicarbonate
25 Bicarbonate pump 119 Filter / concentrate
26 Bypass valve 120 Filter / bicarbonate
29 Degassing pump 121 Central concentrate delivery connector
30 Outlet valve 122 Central bicarbonate delivery connector
31 Balancing chamber valve 1 123 Pressure switch for V102
32 Balancing chamber valve 2 124 Pressure switch for V104
33 Balancing chamber valve 3 130 biBag drain valve
34 Balancing chamber valve 4 132 biBag conductivity cell
35 Balancing chamber valve 5 133 biBag temperature sensor
36 Balancing chamber valve 6 134 biBag pressure transducer
37 Balancing chamber valve 7 136 biBag connector
38 Balancing chamber valve 8 137 biBag micro-switch 1
39 Negative pressure valve 138 biBag micro-switch 2
41 Water inlet valve 148 Filter / rinse valve V100
43 Fill valve 149 Filter / rinse valve V99
54 Heater rod 150 Filter / fill valve
61 Pressure reducing valve 151 Orifice
63 Water inlet filter 181 Temperature compensation plate 2
65 Loading pressure valve 182 Pressure transducer 2
66 Heater block 183 Test valve
66a Water inflow chamber 184 Filter / test valve
66b Heater rod chamber 185 Compressor
66c Float chamber 188 Evacuation valve
68 Balancing chamber 189 Retentate valve
71 Filter / concentrate 190 Online filter
72 Filter / bicarbonate 191 Online valve 3
73 Filter / dialysate ext. 192 Online valve 2
74 Filter / UF 193 Online valve 1
75 External flow indicator 194 Rinse port
76 Filter / fill valve 195 Substituate port
77 Heat exchanger 201 Air separator / concentrate
78 Relief valve 202 Level sensor / concentrate
84 Disinfectant valve 203 Air separator / bicarbonate
85 Disinfectant connector 204 Level sensor / bicarbonate
86 Recirculation valve 205 Mixing point / concentrate / bicarbonate
87 Drain valve 206 Buffer volume chamber
88 Multifunction block 210 Filter
88a Degassing chamber
88b Secondary air separator
88c Primary air separator Hydraulics measuring points:
89 Degassing orifice
90a Rinse chamber / concentrate A Reduced water inlet pressure
90b Rinse chamber / bicarbonate B Balancing chamber loading pressure
91 Rinse valve C Flow pump pressure
92 Vent valve D Degassing pump pressure
94 Concentrate suction tube

Fresenius Medical Care 4008 OCM Supplement 2/10.01 (TM) 3-7

3.3 Calibration mode

3.3.1 Basic conditions

– The hemodialysis machine must be

switched off.
– The service switch must be in the ON
(up) position.
– Turn the hemodialysis machine on.

3.3.2 Display messages (4008 H/S)

CALIBRATION

004.7 Volt Watchdog supply voltage (4.5 V – 5.5 V)

011.9 Volt 12 V voltage (11.5 V – 12.5 V)

023.6 Volt 24 V voltage (23 V – 25 V)

020.4 Volt Battery charging voltage (> 20 V)

7 8 9 0 Esc

4 5 6

1 2 3 C Best

3-8 Fresenius Medical Care 4008 OCM Supplement 2/10.01 (TM)

4 Calibration program

Confirm
CALIBRATION key

▲▼

DIAGNOSTICS

▲▼

MISCELLANEOUS

▲▼

SETUP MENU

▲▼

Fresenius Medical Care 4008 OCM Supplement 2/05.00 (TM) 4-1

 ● Main menu

CALIBRATION

Confirm
key

CAL. ART. PRESSURE

▲▼

CAL. ART. P_MODULE

▲▼

CAL. VENOUS PRESSURE

▲▼

CAL. VEN. P_MODULE

▲▼

CALIB. (B)-PUMP-RATE

▲▼

ADJ. UF-PUMP VOLUME

▲▼

CAL. DEGAS. PRESSURE

▲▼

CAL. FLOW 300 ml/min

▲▼

CAL. FLOW 500 ml/min

▲▼

CAL. FLOW 800 ml/min

▲▼
Confirm
CALIB. TEMPERATURE key see Part 11

▲▼

CAL. MIXING SYSTEM

▲▼
Confirm
CALIB. CONDUCTIVITY key see Part 13

▲▼

CAL. DIAL. PRESSURE

▲▼

CALIBRATE BLD

▲▼

CALIB. BIBAG VALUES

▲▼

RESET FAILURE RECORD

▲▼

NOVRAM

▲▼
Confirm
back to main menu ? key

▲▼

4-2 Fresenius Medical Care 4008 OCM Supplement 2/05.00 (TM)

● Part 11: Calibrating the dialysate temperature

CALIB. TEMPERATURE

Confirm
key

Confirm see Part 11.1

Temp. ADJUSTMENT key

▲▼
Confirm see Part 11.2
Check TEMPERATURE key

▲▼
Confirm see Part 11.3
OCM TEMP.-Check key

▲▼
Confirm
back to menu? key

▲▼

☞ Note
Accuracy of the external meter to be connected: ±0.2 °C.

Fresenius Medical Care 4008 OCM Supplement 2/05.00 (TM) 4-3

 ● Part 11.1: Adjusting the dialysate temperature

Temp. ADJUSTMENT

Confirm
key
adj. temp to 37°C

adj. temp to 37°C

Esc
key
1 XXXX ADC-digits

Connect the external 2 XXXX DAC-digits

reference instrument.
Connect the BIC suction
tube to the BIC container 3 XXXX ADC-digits
or place it in water
of room temperature.
4 XXXX ADC-digits
Adjust the digital value in
the “UF Rate” window ➁ by
pressing the +/– keys.

Wait until the temperature 7 8 9 0 Esc

on the external reference
instrument indicates 37.0 °C. 4 5 6

Tone Mute 1 2 3 C Conf

key

DATA STORED
➀ NTC3; 8 bit
➁ Control 8 bit
approx. 3 sec
➂ NTC3; 12 bit
Esc
OCM TEMP. Adjust key
➃ NTC109; 8 bit,
Machine in bypass if NTC 109 is activated in SETUP

Wait for the temperature

to stabilize (37 °C)
Indicated in "UF rate"
window ➁

Tone Mute OCM TEMP.-Adjust

key

1 XXXX ADC-digits
DATA STORED

approx. 3 sec
2 XXXX °C

3 XXXX ADC-digits

4 XXXX DAC-digits

7 8 9 0 Esc

4 5 6

1 2 3 C Conf

➀ NTC3; 12 bit
➁ NTC3 temperature
➂ NTC4; 12 bit
➃ Dynamic measurement range switching

4-4 Fresenius Medical Care 4008 OCM Supplement 2/05.00 (TM)

● Part 11.2: Checking the dialysate temperature

Check TEMPERATURE

Confirm
key

act temp = 37.0 °C

use  
to select the
Temperature setting field

set temp = XX.X °C

Specify a temperature by
pressing the +/– keys.

Tone mute
key

ACKNOWLEDGED

approx. 3 sec

ACT temp = XX.X °C

Check whether the
preselected temperature
is achieved.
Check: reference instrument,
display and 37.0 °C
LED display correspond
to 115/116 digits in the
“UF Volume” window ➀.
Repeat the Tolerance: ±0.5 °C
procedure
with different
values
Esc
(e.g. 35/39 °C) key

➀ NTC3; 8 bit

act. temp = 37.0 °C ➁

➂ NTC109; temperature
1 XXXX ADC-digits
➃ NTC109; 8 bit
2

3 XXX.X °C

4 XXXX ADC-digits
Alpha Temperature
display adjustment

7 8 9 0 Esc

4 5 6

1 2 3 C Conf

Fresenius Medical Care 4008 OCM Supplement 2/05.00 (TM) 4-5

 ● Part 11.3: Checking the dialysate temperature for OCM

OCM TEMP.-Check

Confirm
key

Open the shunt cover

to switch the machine
to the bypass mode

act temp = 37.0 °C

use  
to select the
Temperature setting field

set temp = XX.X °C

Specify a temperature by
pressing the +/– keys.

Tone Mute
key

ACKNOWLEDGED

approx. 3 sec

ACT temp = XX.X °C

Check whether the
preselected temperature
is achieved.
Check: Display,
37.0 °C bargraph display
Tolerance of the
displayed temperature
in the UF rate field ➁
and the UF time field ➃:
Repeat the ±0.2 °C
procedure
with different
values
Esc
(e.g. 35/39 °C) key

➀ NTC3; 12 bit

OCM Temp.-Check ➁ NTC3; temperature

➂ NTC4; 12 bit
1 XXXX ADC-digits
➃ NTC4; temperature
2 XX.XX °C

3 XXXX ADC-digits

4 XX.XX °C
Alpha Temperature
display adjustment

7 8 9 0 Esc

4 5 6

1 2 3 C Conf

4-6 Fresenius Medical Care 4008 OCM Supplement 2/05.00 (TM)

● Part 13: Calibrating the conductivity

CALIB. CONDUCTIVITY

Confirm
key

Confirm see Part 13.1

CONDUCTIVITY Set key

▲▼
Confirm see Part 13.2
COND. with Concentr. key

▲▼
Confirm see Part 13.3
TEMP/COND COMP Calib key

▲▼
Confirm see Part 13.4
OCM PULSE calib. key

▲▼
Confirm see Part 13.5
CONDUCTIVITY Check key

▲▼
Confirm see Part 13.6
COND Check with Conc key

▲▼
Confirm see Part 13.7
OCM COND.-Check key

▲▼
Confirm see Part 13.8
TEMP/COND COMP Check key

▲▼
Confirm
back to menu? key

▲▼

Fresenius Medical Care 4008 OCM Supplement 2/05.00 (TM) 4-7

 ● Part 13.1: Setting the conductivity

CONDUCTIVITY Set

Confirm
key

Esc
CD set: 12.80 mS/cm key
CD set: 15.70 mS/cm

Use   to
move to the Use   to
Concentrate setting field. move to the
If no key is Concentrate setting field.
Conc. set = ±0 % pressed for If no key is
approx. 4 sec conc. set = –X % pressed for
approx. 4 sec
Use +/– to reduce
the concentrate pump Use +/– to raise
volume to get to a CD in the concentrate pump
the lower display range. volume to get to a CD in
the lower display range.
e.g.:
Conc. set. = –X %
Conc. set. = +10 %

Tone Mute
key Tone Mute
key

ACKNOWLEDGED
ACKNOWLEDGED

approx. 3 sec
approx. 3 sec

CD set: 12.80 mS/cm

CD set: XX.X mS/cm

Wait for the CD to stabilize.

Compare the CD with the Wait for the CD to stabilize.
external reference meter. Compare the CD with the
In case of a deviation, adjust the dis- external reference instrument.
play by pressing the +/– keys. In case of a deviation, adjust the dis-
play by pressing the +/– keys.
Tone Mute
key Tone Mute
key

ACKNOWLEDGED
DATA STORED

approx. 3 sec
approx. 3 sec

➀ CD cell 7; 12 bit / 8 bit alternating

CD set: 12.80 mS/cm ➁

ADC-digits ➂
1 XXXX
[ADC-digits (OCM)]
➃ CD cell 110; 12 bit/ 8 bit alternating
2 XXXX steps
(concentrate pump)

3 XXXX steps
(bicarbonate pump)

4 XXXX ADC-digits
[ADC-digits (OCM)]
Alpha Concentrate Bicarbonate
display setting setting

7 8 9 0 Esc

4 5 6

1 2 3 C Conf

4-8 Fresenius Medical Care 4008 OCM Supplement 2/05.00 (TM)

● Part 13.2: Setting the conductivity with concentrate

COND. with Concentr.

☞ Note
An adjustment of the conductivity using a calibration concentrate is currently
not possible, since a suitable calibration concentrate is not available.

Fresenius Medical Care 4008 OCM Supplement 2/05.00 (TM) 4-9

 ● Part 13.3: Setting the temperature/conductivity compensation

TEMP/COND COMP Calib.

Confirm
key
act temp = XX.XX °C

Machine in bypass 1 XX.XX mS/cm

Esc
act temp = XX.XX °C key 2 XX.XX mS/cm
Verify
that the conductivity of 3 XX.XX mS/cm
both measuring cells in the
"UF rate" (➁) and the "UF time"(➃)
window is identical and that it is 4 XX.XX mS/cm
within 13.9 to 14.5 mS/cm.
Alpha Concentrate Bicarbonate Temperature
If the conductivity is display setting setting adjustment
outside the limits:
use   to select
the concentrate setting 7 8 9 0 Esc
field
4 5 6
If no key is
conc. set = ±0 % pressed for 1 2 3 C Conf
approx. 4 sec
Use +/– to reduce/increase
the concentrate pump volume
until the conductivity is
inside the alarm limits act temp = XX.XX °C
13.9 – 14.5 mS/cm

1 XX.XX mS/cm
conc. set = +X %

Tone Mute
2 XX.XX mS/cm
key
3 XX.XX mS/cm
ACKNOWLEDGED

4 XX.XX mS/cm
approx. 3 sec
Alpha Temperature
act temp = XX.XX °C display adjustment

Verify that the preset 7 8 9 0 Esc

temperature of 35 °C is achieved
and that it has stabilized. 4 5 6
Check: Display,
LED bargraph display 1 2 3 C Conf
Tolerance: ±0.5 °C

Tone Mute ➀ CD cell 7,

key
Value in mS/cm after confirmation of 35°C
ACKNOWLEDGED
➁ CD cell 7, current value in mS/cm
approx. 3 sec ➂ CD cell 110,
Value in mS/cm after confirmation of 35°C
act temp = XX.XX °C
➃ CD cell 110, current value in mS/cm
Verify that the preset
temperature of 39 °C is achieved
and that it has stabilized.
Check: Display,
LED bargraph display
Tolerance: ±0.5 °C

Tone Mute
key

DATA STORED

approx. 3 sec

4-10 Fresenius Medical Care 4008 OCM Supplement 2/05.00 (TM)

● Part 13.4: OCM pulse calibration

OCM PULSE calibr.

Verify that the

conductivity is
within13.9 to 14.6 ms
and wait for the
conductivity to stabilize.

Confirm
key

Start PULSE calib.? Esc

key

Tone Mute
key

OCM PULSE UP activ Esc

key

Positive OCM pulse

duration

OCM PULSE DOWN activ Esc

key

Negative OCM pulse

duration

OCM PULSE finished

approx. 3 sec

Tone mute
LED is flashing.
Info sound

pos. Dialy: –XXXX.X neg. Dialy: XXXX.X

☞
alternating

Tolerance per pulse: ±25

Note
If the value is outside ±25,
Tone Mute check the conductivity mea-
key
suring system of the dialysis
DATA STORED
system.

approx. 3 sec

➀ Time elapsed since the pulse calibration

was started
OCM PULSE UP activ
➁ Counter
1 XXXX Seconds ➂ Concentrate setting
2 XXXX Index ➃ CD cell 7,
compensated CD value
3 XXXX

4 XXXX mS/cm

7 8 9 0 Esc

4 5 6

1 2 3 C Conf

Fresenius Medical Care 4008 OCM Supplement 2/05.00 (TM) 4-11

 ● Part 13.5: Conductivity check

CONDUCTIVITY Check

Confirm
key

act. cond: XX.X mS/cm

use   to select
the Concentrate
setting field

If no key is
conc. set = ± 0% pressed for
approx. 4 sec
Use the +/– keys
to reduce the
concentrate pump volume
e.g.:
conc. set = –6 %

Tone Mute
key

ACKNOWLEDGED

approx. 3 sec

act. cond: XX.X mS/cm

Verify the conductivity.
Check:
Reference meter, display,
Repeat the LED bargraph display
procedure with
different values
Esc
key

➀ CD cell 7; 12 bit / 8 bit alternating

act. cond: XX.X mS/cm ➁

ADC-digits ➂
1 XXXX [ADC-digits (OCM)]
➃ CD cell 110; 12 bit / 8 bit alternating
2 XXXX steps
(concentrate pump)

3 XXXX steps
(bicarbonate pump)

4 XXXX ADC-digits
[ADC-digits (OCM)]
Alpha Concentrate Bicarbonate Temperature
display setting setting adjustment

7 8 9 0 Esc

4 5 6

1 2 3 C Conf

4-12 Fresenius Medical Care 4008 OCM Supplement 2/05.00 (TM)

● Part 13.6: Conductivity test with concentrate

COND Check with Conc

☞ Note
A calibration of the conductivity using a calibration concentrate is currently not
possible, since a suitable calibration concentrate is not available.

Fresenius Medical Care 4008 OCM Supplement 2/05.00 (TM) 4-13

 ● Part 13.7: OCM conductivity check

OCM COND.-Check

Confirm
key

OCM Cond.-Check

Use   to
select the
concentrate setting field

If no key is
conc. set = ± 0% pressed for
approx. 4 sec
Use the +/– keys
to reduce the
concentrate pump volume.
e.g.:
conc. set = –6 %

Tone Mute
key

ACKNOWLEDGED

approx. 3 sec

OCM Cond.-Check
Verify the conductivity.
Check:
Reference meter, display,
Repeat the LED bargraph display
procedure with
different values
Esc
key

➀ CD cell 7; 12 bit

OCM Cond.-Check ➁ CD cell 7

➂ CD cell 110;12 bit
1 XXXX ADC-digits (OCM)
➃ CD cell 110
2 XX.XX mS/cm

3 XXXX ADC-digits (OCM)

4 XX.XX mS/cm
Alpha Concentrate Bicarbonate Temperature
display setting setting adjustment

7 8 9 0 Esc

4 5 6

1 2 3 C Conf

4-14 Fresenius Medical Care 4008 OCM Supplement 2/05.00 (TM)

● Part 13.8: Temperature/conductivity compensation check

TEMP/COND COMP Check

Confirm
key

act temp = XX.XX °C

The individual
conductivities and their
compensation factors are
displayed in the fields
(see 4008 H/S)

The conductivity cells

can be crosschecked
by changing the
concentration
or temperature.

Esc
key

➀ CD cell 7, compensated
act temp = XX.XX °C ➁ CD cell 7, compensation factor
➂ CD cell 110, compensated
1 XX.XX mS/cm
➃ CD cell 110, compensation factor
2 XXXX mS/(cm•°C)

3 XX.XX mS/cm

4 XXXX mS/(cm•°C)
Alpha Concentrate Bicarbonate Temperature
display setting setting adjustment

7 8 9 0 Esc

4 5 6

1 2 3 C Conf

Fresenius Medical Care 4008 OCM Supplement 2/05.00 (TM) 4-15

4-16 Fresenius Medical Care 4008 OCM Supplement 2/05.00 (TM)
6 Setup Menu

6.1 Overview

CALIBRATION

▲▼

DIAGNOSTICS

▲▼

MISCELLANEOUS

▲▼
Confirm
SETUP MENU key

▲▼

Fresenius Medical Care 4008 OCM Supplement 2/05.00 (TM) 6-1

6.2 Main menu 4008 H/S

SETUP MENU

Confirm
key

SET ALARM/WARN TIME ACTIV. STD UF-DATA

▲▼ ▲▼

SETUP CLEANING PGM SET STD. PRIME-TIME

▲▼ ▲▼

SETUP DILUTION SOUND I/O-SWITCH

▲▼ ▲▼

SET CONDUCT. LIMIT SET KEY-CLICK

▲▼ ▲▼

INFO SOUND (C-PGM) BPR/UFR–WARNING

▲▼ ▲▼

SET DIAL PARAMETERS SET RINSE–VOLUME

▲▼ ▲▼

CALC. CUMUL. BLOOD-VOL T1–TEST AUTOSTART

▲▼ ▲▼

HAEMOGLOBIN UNIT ONLINE plus SETTINGS

▲▼ ▲▼
Confirm see Part 9
OCM SETTINGS key SET CENTRAL-DELIVERY

▲▼ ▲▼

AUTOM. SN-START STORE DEFAULT VALUES

▲▼ ▲▼
CONFIRM
ACTIV. MONIT_NTC109 BACK TO MAIN MENU ? KEY

▲▼ ▲▼

6-2 Fresenius Medical Care 4008 OCM Supplement 2/05.00 (TM)

● Part 9: OCM Settings

OCM SETTINGS

Confirm
key

Confirm see Part 9.1

OCM MEASUREMENT key

▲▼
Confirm see Part 9.2
OCM ZERO MEASUREMENT key

▲▼
Confirm see Part 9.3
OCM DELAY TIME key

▲▼
Confirm see Part 9.4
OCM CLR CORR FACTOR key

▲▼
Confirm see Part 9.5
OCM BASELINE DIFF key

▲▼
Confirm see Part 9.6
OCM INTEGRAL VALUE key

▲▼
Confirm see Part 9.7
OCM KT/V WARNLEVEL key

▲▼
Confirm
back to menu? key

▲▼

● Part 9.1: Activating the OCM measurement

OCM MEASUREMENT

Confirm
key

Tone Mute After

OCM Measurement: OFF key DATA STORED approx. 3 sec
(Default: OFF) Esc
+/– key

Tone Mute After

OCM Measurement: ON key DATA STORED approx. 3 sec
Esc
+/– key

Fresenius Medical Care 4008 OCM Supplement 2/05.00 (TM) 6-3

 ● Part 9.2: Activating the OCM zero measurement

OCM ZERO MEASUREMENT

Confirm
key

Tone Mute After

OCM Zero Measurement: ON key DATA STORED approx. 3 sec
(Default: ON) Esc
+/– key

Tone Mute After

OCM Zero Measurement: OFF key DATA STORED approx. 3 sec
Esc
+/– key

☞ Note
If the OCM zero measurement is set to “OFF”, the OCM option will be deacti-
vated.
When the OCM zero measurement is reactivated (ON) it is imperative to per-
form an OCM pulse calibration.

● Part 9.3: Setting the OCM delay time

OCM DELAY TIME

Machine Hydraulic unit type Time
Confirm
key
4008 H AutoPRIME™ 15 sec
Delay Time: XX s
Esc
key
4008 H ONLINEplus™ 65 sec
Use +/– to set the value
shown in the table on the right 4008 S AutoPRIME™ 18 sec
(1 – 70 seconds)
4008 S ONLINEplus™ 67 sec
Tone Mute
key

DATA STORED

After approx. 3 sec

6-4 Fresenius Medical Care 4008 OCM Supplement 2/05.00 (TM)

● Part 9.4: Setting the OCM correction factor

OCM CLR CORR FACTOR

Confirm
key

Esc
ClrCorr Factor: 1.000 key

The value displayed

is the
default value

Tone Mute
key

DATA STORED

After approx. 3 sec

☞ Note
Do not change the default value.

☞ Note
In 4008 H/S machines it is generally possible to define a correction factor for
all clearance measurements. This feature has been provided to be able to
adapt a machine at its place of installation to latest knowledge gained from
scientific discussion that has not been completed yet. Based on present know-
ledge the correction factor for Fresenius Polysulfone membranes must be ad-
justed to “1” (factory setting). The accuracies specified are only applicable for
Fresenius Polysulfone membranes in combination with a correction factor that
was set to “1”.

● Part 9.5: Setting the OCM baseline difference

OCM BASELINE DIFF

Confirm
key

Esc
Base Diff.: 0.015 ms/cm key

The value displayed

is the
default value

Tone Mute
key

DATA STORED

After approx. 3 sec

☞ Note
Do not change the default value.

Fresenius Medical Care 4008 OCM Supplement 2/05.00 (TM) 6-5

 ● Part 9.6: Setting the OCM integral value

OCM INTEGRAL VALUE

Confirm
key

Esc
Integral value: 55 key

The value displayed

is the
default value

Tone Mute
key

DATA STORED

After approx. 3 sec

☞ Note
Do not change the default value.

● Part 9.7: Setting the OCM KT/V warning level

OCM KT/V WARNLEVEL

Confirm
key

Esc
Kt/V Warnlevel: 85 % key

Use +/– to set the

warning level
(Default: 85)
Range: 0 – 99 %
0 = no warning

Tone Mute
key

DATA STORED

After approx. 3 sec

6-6 Fresenius Medical Care 4008 OCM Supplement 2/05.00 (TM)

Table of Contents 8 Circuit diagrams

Section Page

8.1 Circuit diagrams and component layout LP 632, CPU 2 .......................................... 8-3

8.2 Circuit diagrams and component layout LP 633-5, Input board ............................. 8-19

Fresenius Medical Care 4008 OCM Supplement 2/10.01 (TM) 8-1

8-2 Fresenius Medical Care 4008 OCM Supplement 2/10.01 (TM)
8.1 Circuit diagrams and component layout LP 632, CPU 2
LP 632, CPU2 Component layout

Fresenius Medical Care 4008 OCM Supplement 2/10.01 (TM) 8-3

8-4 Fresenius Medical Care 4008 OCM Supplement 2/10.01 (TM)
 LP 632, CPU 2
Circuit diagram 1/7

Fresenius Medical Care 4008 OCM Supplement 2/10.01 (TM) 8-5

8-6 Fresenius Medical Care 4008 OCM Supplement 2/10.01 (TM)
 LP 632, CPU 2
Circuit diagram 2/7

Fresenius Medical Care 4008 OCM Supplement 2/10.01 (TM) 8-7

8-8 Fresenius Medical Care 4008 OCM Supplement 2/10.01 (TM)
 LP 632, CPU 2
Circuit diagram 3/7

Fresenius Medical Care 4008 OCM Supplement 2/10.01 (TM) 8-9

8-10 Fresenius Medical Care 4008 OCM Supplement 2/10.01 (TM)
 LP 632, CPU 2
Circuit diagram 4/7

Fresenius Medical Care 4008 OCM Supplement 2/10.01 (TM) 8-11

8-12 Fresenius Medical Care 4008 OCM Supplement 2/10.01 (TM)
 LP 632, CPU 2
Circuit diagram 5/7

Fresenius Medical Care 4008 OCM Supplement 2/10.01 (TM) 8-13

8-14 Fresenius Medical Care 4008 OCM Supplement 2/10.01 (TM)
 LP 632, CPU 2
Circuit diagram 6/7

Fresenius Medical Care 4008 OCM Supplement 2/10.01 (TM) 8-15

8-16 Fresenius Medical Care 4008 OCM Supplement 2/10.01 (TM)
 LP 632, CPU 2
Circuit diagram 7/7

Fresenius Medical Care 4008 OCM Supplement 2/10.01 (TM) 8-17

8-18 Fresenius Medical Care 4008 OCM Supplement 2/10.01 (TM)
8.2 Circuit diagrams and component layout LP 633-5
LP 633-5, Input board Component layout

Fresenius Medical Care 4008 OCM Supplement 2/10.01 (TM) 8-19

8-20 Fresenius Medical Care 4008 OCM Supplement 2/10.01 (TM)
 LP 633
Circuit diagram 1/8

Fresenius Medical Care 4008 OCM Supplement 2/10.01 (TM) 8-21

8-22 Fresenius Medical Care 4008 OCM Supplement 2/10.01 (TM)
 LP 633
Circuit diagram 2/8

Fresenius Medical Care 4008 OCM Supplement 2/10.01 (TM) 8-23

8-24 Fresenius Medical Care 4008 OCM Supplement 2/10.01 (TM)
 LP 633
Circuit diagram 3/8

Fresenius Medical Care 4008 OCM Supplement 2/10.01 (TM) 8-25

8-26 Fresenius Medical Care 4008 OCM Supplement 2/10.01 (TM)
 LP 633
Circuit diagram 4/8

Fresenius Medical Care 4008 OCM Supplement 2/10.01 (TM) 8-27

8-28 Fresenius Medical Care 4008 OCM Supplement 2/10.01 (TM)
 LP 633
Circuit diagram 5/8

Fresenius Medical Care 4008 OCM Supplement 2/10.01 (TM) 8-29

8-30 Fresenius Medical Care 4008 OCM Supplement 2/10.01 (TM)
 LP 633
Circuit diagram 6/8

Fresenius Medical Care 4008 OCM Supplement 2/10.01 (TM) 8-31

8-32 Fresenius Medical Care 4008 OCM Supplement 2/10.01 (TM)
 LP 633
Circuit diagram 7/8

Fresenius Medical Care 4008 OCM Supplement 2/10.01 (TM) 8-33

8-34 Fresenius Medical Care 4008 OCM Supplement 2/10.01 (TM)
 LP 633
Circuit diagram 8/8

Fresenius Medical Care 4008 OCM Supplement 2/10.01 (TM) 8-35

8-36 Fresenius Medical Care 4008 OCM Supplement 2/10.01 (TM)