TEST BLUEPRINT

MLS 007 - Cytogenetics Comprehensive Examination

Weight Justification:
The weight of each question assigned in a content area matches with the learning outcomes of the course.

Weight Justification
Content Area Weight Justification

History of 10% The content area focuses on the beginning of Cytogenetics. This area talks
Cytogenetics about the prominent scientists and their contributions to the field.

DNA, 10% The topic focuses on the molecule Deoxyribonucleic Acid as the raw material
Chromosomes and of inheritance. From there, the topic moves on to how this genetic material is
Cell Cycle compacted to fit even the smallest chromosome. Cell cycle then follows to be
able to know how DNA is copied and distributed to newly created cells.

Chromosomal 20% The content focuses on describing karyotypes, naming and interpreting
Aberrations numerical and structural chromosome aberrations as part of the advancements
in the methodology of Cytogenetics.

Mendelian and 20% The topics focus on the patterns of inheritance as discovered by Mendel and
Non-Mendelian some principles of inheritance that are beyond Mendel’s laws. Making
Inheritance Punnett squares, identifying the genotypic and phenotypic ratios as well as
defining Non-Mendelian terms are included in these areas.

Examining and 20% The content describes the basic techniques in examining and analyzing
Analyzing chromosomes. Aside from introducing the common and advance techniques,
Chromosomes the topic teaches the students how to collect, handle, transport and process
specimens.

Cancer 20% The topic focuses on the Genetics of Cancer, the role of cell cycle and the
Cytogenetics characteristics of cancer cells.

Test Blueprint of Cytogenetics Comprehensive Examination S.Y. 2019-2020

Content Area Weight Recall Comprehension Analysis

History of Cytogenetics 10% 5 5

DNA, Chromosomes and Cell Cycle 20% 10 10

Chromosomal Aberrations 20% 20

Mendelian and Non-Mendelian Inheritance 20% 10 10

Examining and Analyzing Chromosomes 10% 5 5

Cancer Cytogenetics 20% 20

100% 20 50 30

Prepared by: Rolaine Ann A. Polo, RMT, MPH