Mindanao State University – Iligan Institute of Technology Student: _________________________ Section:___________

PHARMACOLOGY

DRUG STUDY

Brand Name: __Tekturna__ Generic Name: Aliskiren Drug Classification: DIRECT RENIN INHIBITOR

Dosage, Route & Frequency Drug-Drug & Drug- Side Effects

Drug Action Indications Contraindications Adverse Reactions (By System)
Recommended Prescribed Food Interactions (By System)
Renin inhibitor aliskiren, lithium, Aliskiren is the first Who should not GI: GI:
that inhibits the drugs that may in a class of drugs take Aliskiren 300 diarrhea, stomach diarrhea, stomach pain.
Adult: conversion of increase the level of called direct renin Mg Tablet pain.
Respiratory:
angiotensinogen to potassium in the inhibitors. Its current Angiotensin Respiratory: cough.
150 mg PO qDay,
may increase to angiotensin I. The blood (such as ACE licensed indication is Inhibiting Agents? cough.
300 mg PO qDay decrease in inhibitors including essential (primary) rash.
based on response hypertension. While -low amount of rash.
antiotensin I benazepril/lisinopril, CNS:
and tolerability used for high blood sodium in the blood.
causes a decrease birth control pills CNS: dizziness, headache.
pressure, other better -high levels of dizziness,
Pediatric: in angiotensin II, a containing
studied medications potassium in the headache.
potent blood drospirenone).
-<2 years: are typically blood.
pressure elevating recommended due to
Contraindicated -low blood pressure.
peptide concerns of higher
-2 to <6 years: -a type of allergic
Safety and efficacy side effects and less
reaction called
not established evidence of benefit.
-6 to 17 years angioedema.
<20 kg: Not -pregnancy.
recommended -decreased blood
20 to <50 kg: volume.
Starting dose is 75 -moderate to severe
mg PO qDay; not
kidney impairment.
to exceed 150 mg
PO qDay
≥50 kg: 150 mg PO
qDay; may
increase to 300 mg
PO qDay

Responsibilities in the Nursing Process (ADPIE) Responsibilities in the Nursing Process (ADPIE)

https://www.drugbank.ca/drugs/DB09026
https://medlineplus.gov › druginfo › meds
https://reference.medscape.com/drug/tekturna-aliskiren-342329
https://lookaside.fbsbx.com/file/DRUG%20CLASSIFICATION%20FINAL.pdf?token=AWz7E8QTe6FfP9IZ2Pz4YWVjqxMxI2jzYtGsNtXxJVm2RNghyBdOIX5G5Oc-
5NhkoJPmzBuPBs9BPozLNpYTsIXBCIXsmGSMlgJM7bap2fgyNKsrqhHRPVJuV2-iiEN8L2sm1D0bSCJIhpDJsuCpeVIs