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1 Title A COMPARATIVE CLINICAL STUDY ON THE EFFECT OF RASNASAPTAK KWATH
AND VISHWADI KWATH IN KATIGRAHA
2 Research Is there any difference between the effect of Rasnasaptak Kwath and Vishwadi Kwath on
Question Katigraha?

3 Null Hypothesis-
Hypothesis
- There is no significant difference between the effect of Rasnasaptak Kwath and Vishwadi
kwath in Katigraha.

Alternative Hypothesis-
-There is significant difference between the effect of Rasnasaptak Kwath and Vishwadi
kwath in Katigraha.

4 Introduction Vata, Pitta and Kapha are the three doshas mentioned in Ayurveda. These
tree doshas either vitiated or decreased causes the vydadhi. Vata, the one among the
three doshas is said to be superior most in all aspects as it affects the action and
movement of the other two doshas as well as all the dhatus etc. Vata is mainly present in
Pakvashay,KATI, sakthi,shrotra,asthi,sparshanendriyam.

uÉÉrÉÑ: ÌmɨÉÇ MüTü¶ÉåÌiÉ §ÉrÉÉå SÉåwÉÉ: xÉqÉÉxÉiÉ: |

ÌuÉM×üiÉÉÅÌuÉM×üiÉÉ SåWûÇ blÉÎliÉ iÉå uÉiÉïrÉÎliÉ cÉ ||
(A.¾û.xÉÔ.1/6)

Katigraha is considered as one among the 80 Vata Nanatmaja vikara by

Sharagdhara Samhita. Katigraha is explained as separate disease in Ayurvedic classical
text ‘Gada Nigraha’. The lakshana of Katigraha are Shoola and Sthambha/graha in Kati
Pradesh. When Vata vitiated by many hetus enters into Kati Pradesh, it produces the
symptoms like shoola and sthabdhata/graha in kati Pradesh, that condition is called as
Katigraha.
Locomotion is one of the prime necessities of every human being. Katigraha is
one of the vatavyadhi which affect the normal function of locomotion. Even though this
disease, not being a life threatening one, it hampers daily activity of the person. According
to a survey Katigraha i.e. low backache is extremely common and second only to the
common cold. It is very common in both male and female equally.

NEED FOR THE STUDY

The number of patients suffering with Katigraha is increasing day by day. It
occurs due to stressful work hours, improper seating posture during work, sitting in one
posture for a long time, lack of stretching/exercise, long travels on 2/4 wheelers etc. It can
be considered as low backache, which disturbs the routine work of an individual.
As the medical science recognized the severity of katigraha, medicine which
relieves the pain, stiffness, improves the functional ability, restores functional disability and
controls the condition with cost effectiveness is the need of the century.
 Ranasaptak Kwath and vishwadi kwath are mentioned in Sharangdhar Samhita
and sahastrayoga respectively for treatment of all kinds of vata vyadhi including katigraha.
To find out the more effective medicine among the two which will help in reduction of
symptoms of katigraha fastly, with no complications is necessary so that it can be more
precisely used in the treatment of katigraha,making it the drug of choice in katigraha
among these two, this study is necessary.

5 Review of The literature for my dissertation will be reviwed from Ayurvedic classical textbooks,
Literature Modern textbooks and various recent and past researches andfrom internet.

5.1 References for review of literature-

On Katigraha-
- Bhatt Mrunalini R.-Study of erandamool basti inmanagement of katigraha;Jamnagar
University,1997.

- Dhongade S.-Katigraha pe katibasti ki upayogita; Govt. Ayurved college

Nagpur,1998

- Management of kati graham with Vitex negundo; Govt. Ayurved college,Trivendrum,

1984
- Pattanayali S.- Clinical study on katigraha with ghrita tailadi yoga; Gopabandhu
Ayurvedic Mahavidyalaya,1999.

- Prema p. - Management of katigraha due to kati kasheruka antareeya chakrika

(lumbar disc prolapses); Govt. Ayurved college,Trivendrum, 1992

- Keeriyoth Sajitha- A study on the effect of nature cure technique in the management
of katigraha; Govt. Ayurved college,Trivendrum, 1995

- Vitalkar Pranoti- Prushthavanshgat Kati Kasherukancha Rachanatmak abhyas va

sandarbhit Katigraha;2004

- A study of structural changes in Katikasheruka (lumbar vertebrae) in heavy vehicle

drivers with special reference to Katigraha (low back pain); 2011

- Study the efficancy of shwadanshtradi matra basti in katigraha with special

reference to lumbar spondylosis;2016

On Rasnasaptak Kwath
- Saha A.- A role of Rasna saptak kwath in amavata;1994
- Devi Poornima- Clinical study of amavata and its management by Ranasaptak
Kwath and indeginous compound;2002.
- Patil J S—The comparative study of individual and combined effect of Brihat
simhananda guggul and Rasna saptak kwath;2003
- A comparative study of mahaushadhadi kwath and rasnasaptak kwath on amavata
w.s.r. to rheumatoid arthritis;2015
5.2 Disease review- Katigraha is explained as separate disease in Ayurvedic classical
text ‘Gada Nigraha’. Katigrahais one of the 80 Nanatmaja Vatavyadhi mentioned by
Acharya Sharangadhara. None of Brihatrayee has explained Katigraha as a separate
entity. But a brief description of Katigraha as a disease with its Lakshana and Chikitsa is
available in Bhavaprakasha, Yogaratnakara and Vrindamadhava has given about the
same symptoms of Katigraha and describes its treatment in detail 5.
In Charaka Samhitha, Sushrutha Samhitha and Astanga Hrudaya, in Nanatamaja
Vata Vyadhi though Katigraha has not been mentioned, other symptoms of spinal diseases
like Prusthagraha, Trikagraha, Manyagraha etc are found, and also mentioned as a
symptom in some diseases.
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MüÌOûaÉëWû: xÉ ÌuÉ¥ÉårÉ: ...... || 160 ||
(aÉSÌlÉaÉëWû uÉÉiÉUÉåaÉÉÍkÉMüÉU MüÉrÉÍcÉÌMüixÉÉ ZÉhQåû 19/160)

Shuddha saam vata when entered in the Katipradesha causes pain,stiffness

then it is called as Katigraha.
1. The conceptual part of literary review of Katigraha from Ayurvedic aspect will be
elaborated in detail.
2. Previous information of Katigraha will be collected from research articles, journals
and internet.

5.3 Drug review

A) Group A- Rasnasaptak Kwath-
UÉxlÉÉxÉmiÉMü YuÉÉjÉ
UÉxlÉÉ aÉÉå¤ÉÑUMæüUhQûSåuÉSÉà mÉÑlÉlÉïuÉÉ |
aÉÑQÒûcrÉÉUauÉkɶÉæuÉ YuÉÉjÉqÉåwÉÉÇ ÌuÉmÉÉcÉrÉåiÉç ||
vÉÑhPûÏcÉÔhÉåïlÉ xÉÇrÉÑ£üÇ ÌmÉoÉåeeÉXûÉMüÌOûaÉëWåû |
mÉɵÉïmÉ׸ÉåÃmÉÏQûÉrÉÉqÉÉqÉuÉÉiÉå xÉÑSÒxiÉUå ||
(vÉÉUÇaÉkÉU qÉ.ZÉÇ. 2/86-87)

The following table shows the contents and the pramana of the drugs.
Ingredient Quantity
Rasna 1.part
Gokshur 1 part
Eranda 1 part
Devdaru 1 part
Punarnava 1 part
Amruta 1 part
 aragvadh 1 part
shunthi prakshep
Following table shows the Karmukatva of the kwath.
Sr. Drug Latin Name Rasa Virya Vipak Guna
No.
1 Rasna Pluchea lanceolata Tikta Ushna Katu Guru
2 Eranda Ricinus communis Madhur Ushna Madhur Guru
Katu Snigdha
Kashay Tikshna
3 Devdaru Cedrus deodar Katu Ushna Katu Laghu
Tikta Snigdha
4 Punarnava Boerhavia diffusa Madhur Ushna Katu Laghu
Tikta Ruksha
5 Amruta Tinospora cordifolia Tikta Ushna Madhur Laghu
Kashay Snigdha
6 Aragvadh Cassia fistula Madhur Sheet Madhur Guru
Snigdha
7 Gokshur Tribulus terrestris Madhur Sheet Madhur Guru
Snigdha
8 Shunthi Zinziber officinale katu ushna Madhur Laghu
Snigdha

B) Group B- Vishwadi Kwath-

ÌuɵÉÉÌS YuÉÉjÉ
ÌuɵÉÉåÃoÉÔMüSvÉqÉÔsÉrÉuÉÉqpÉxÉÉ iÉÑ -
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mÉYuÉÉvÉrÉÉÇxÉpÉ×vÉÃaÉeuÉUaÉÑsqÉvÉÑsÉÏ ||
(xÉWûx§ÉrÉÉåaÉ 1/500)

Ingredient Quantity
Vishwa 1 part
Eranda 1 part
Dashmoola 1 part
Yava 1 part
Kshardvaya Prakshep
(Sajjikshar,Yavaks
har), Hingu,
Lavanatray
(saindhav,
sauvarchal, beed),
pusharmool
choorna
 Sr. Drug Latin Name Rasa Virya Vipak Guna
No.
1 Agnimantha Clerodendrum Katu Ushna Katu Laghu
phlomidis Tikta, Ruksha
Madhur
2 Shyonak Oroxylum indicum Madhur Ushna Katu Laghu
Tikta Ruksha
Kashay
3 Bruhati Solanum indicum Katu, Ushna Katu Laghu
Tikta Ruksha
4 Bilva Aegal marmelos Kashay, Ushna Katu Ruksha
Tikta Laghu
5 Patala Stereosprmum Tikta Anush Katu Laghu
sauvealens Kashay na Ruksha
6 Kantakari Solanum Tikta Ushna Katu Laghu
xanthocarpum Katu Ruksha
7 Gambhari Gmelia arborea Tikta Ushna Katu Guru
Kashay
Madhur
8 Shalaparni Desmodium Madhur Ushna Madhur Guru
gangeticum Tikta Snigdha
9 Prushniparni Uraria picta Madhur Ushna Madhur Laghu
Tikta Snigdha
10 Yava Hordeum vulgare Kashay Sheet Katu Ruksha
Madhur Laghu
11 Pushkarmula Inula racemosa Katu ushna katu Laghu
tikta tikshna
12 Hingu Ferula foetida katu ushna katu Laghu
Snigdha
tikshna
C) Collection And Standardization Of Drugs-

Authentication &identification of all raw materials will be done in Dept.of Dravyaguna &
Dept of Rasashstra and Bhaishajya Kalpana of our college

D) Preparation Of Drug-
mÉÉlÉÏrÉÇ wÉÉåQûvÉaÉÑhÉÇ ¤ÉÑhhÉå SìurÉmÉsÉå ͤÉmÉåiÉç |
qÉ×imÉɧÉå YuÉÉjÉrÉåSè aÉëɽqÉ·qÉÉÇvÉÉuÉvÉåÌwÉiÉqÉç || 1 ||
iÉieÉsÉÇ mÉÉrÉrÉåkSÏqÉÉlMüÉåwhÉqÉç qÉײÎalÉxÉÉÍkÉiÉqÉç |
´ÉÑiÉ: YuÉÉjÉ: MüwÉÉrÉå¶É ÌlÉrÉÑïWû: xÉ ÌlÉaɱiÉå ||2||
(vÉÉ.xÉÇ.qÉ.ZÉÇ. 2/1,2)

Kwath of both will be prepared by the method of preparation of Kwath

described in Sharangdhar Samhita dravya will be taken 1 part, 16 parts of water will be
added and boiled till 1/8th part remains.
 All the drugs will be taken in equal quantity for both the kwathas. 20 grams of drugs will be
taken and 320ml of water will be added and boiled till 40 ml kwath remains. The remaining
kwath will be filtered and will be asked to drink in tolerable form.
The procedure of making kwath will be given to the patients which is mentioned in
adjoining annexure.

E) Drug Administration-

Drug No.of Dose Route Kala Duration follow up

patients

GROUP Rasnasaptak 30 40ml oral Apanou 60 Days 15,30,45,60

A kwath

GROUP Vishwadi 30 40ml oral Apanou 60 Days 15,30,45,60

B Kwath

6 6.1 Primary Objectives-

Objectives
Compare the effect of Rasnasaptak Kwath and Vishwadi Kwath in Katigraha

6.2 Secondary Objectives-

1. To study Katigraha from Ayurvedic classical texts

2. To study the karmukatva of Rasnasaptak Kwath and vishwadi kwath in detail from
classical texts.
3. To study the effect of Rasnasaptak kwath and Vishwadi Kwath on signs and symptoms
of Katigraha.

7 Methodolog 7.1 Type Of Study Design- Randomized open comparative clinical study.
y
7.2 Location Of Study-
For this study subjects will be selected from O.P.D/I.P.D of our college

7.3 DURATION OF STUDY-

Duration of administration of drug- 60 days, follow up on 15th, 30th, 45th & 60th day.
Total duration of study and observation- 18 months

7.4 Method of selection of study subjects-

a)Inclusion Criteria-
1. Age group between 20-70
2. Both genders i.e. male & female
3. Presence of classical features of katigraha
4. Patients of katigraha fulfillimg the samprapti of katigraha i.e shuddha aam vata
enterimg in the katipradesh causing pain,stiffness

b)Exclusion Criteria-
1. Patients With known case of low backache due to any
infection,cancerous,congenital,vascular diseases.
2. Patients associated with any known case of other systemic disorder.
3. Pregnant or lactating women.
4. Patients not willing for trial.

7.5 Method of selection of comparison-

60 patients of Katigraha will be devided into two groups as follows
Following table shows the method of selection of comparison

Sr. No Group Number of patients Treatment

1 Group A 30 Rasnasaptak Kwath
2 Group B 30 Vishwadi Kwath

7.6- matching Criteria-

Katigraha of both groups.

7.7- Operational Definitions-

A) Gradation of Parameters

Subjective Parameters

1. Katishoola- Sr Description Grade

.
A No pain 0

B Mild pain 1
Occasional pain, can be managed
without the drug
C Moderate 2
Frequent pain, can be managed with
drug
D Severe 3
Persistent pain, unmanagable with
drug
 2. Katigraha-
Sr. Description Grade

A No stiffness 0

B Mild stiffness 1
Occasional stiffness, can be managed
without the drug
C Moderate stiffness 2
Frequent stiffness, can be managed with
drug
D Severe stiffness 3
Persistent stiffness, unmanageable with
drug

Objective parameters-
Sr. Description Grade
3. SLR Test-
A More than 90 0

B 61-90 1

C 31-60 2

D Upto 30 3
 4. Walking time-
Time taken by the patient to walk a distance of 100 meters is noted.

Sr. Description Grade

A Excellent 0

B Moderately 1
improved
C Mildly improved 2

D Not improved 3

5. Tenderness -
Sr. Description Grade

A No tenderness 0

B Tender but 1
bearable
C Tender and winced 2

D Tender, winced and 3

withdraw

Follow up-
Sr. no Symptom/ Day 0 Day 15 Day 30 Day 45 Day 60
Sign
1 Katishoola
2 Katigraha
3 SLR
4 Walking
Time
5 Tenderness

7.8 Specification of instrument and related measurements-

Meter scale
8 8.1 Sample Size- Prevalence rate of Katigraha in rural area is about 1.5% of population in
Research
Methodolog rural area.
y specified
& explained As per Daniel formula:
for data n = z2 p(1-p)
collection d2
n= 60

The sample size for present study will be 60. Further those patients will be matched and
divided into two equal groups viz. group A & group B.

8.2 Sampling Technique-

Simple random sampling technique(SRS)- 60 Patients will be randomly selected from

OPD/IPD of our college

8.3 Methods For Data Collection-

Data will be collected with the help of history taking,physical examination of the patients. It
will be done at day 0 and at every follow up and will be noted in follow up table.

8.4 Data Collection Tool-

Case record form

8.5 Data management & analysis procedure-

Collected data will be presented in the form of graphs, tables and charts.

8.6 Plans for Statistical Analysis-

Wilcoxon signed rank test will be used for efficacy of drugs at 5% level of
significance.
For comparative study of drugs Mann Whitney ‘U’ test will be applied at 5%
level of significance. Other suitable test will be applied whenever necessary.

8.7 Overall Assessment Criteria-

Marked improvement 75% to 100% relief in the symptoms

Moderate improvement 50%-74% relief in the symptoms
Mild improvement 25 %to 49% relief in the symptoms
Poor improvement <25% relief in the symptoms

Withdrawal Criteria-

1. It may be considered as – or + 5 another patients

2. Patients who will discontinue the treatment
3. Patients unwilling to take the treatment during study
 4. Patients showing any type of adverse effect

8.8 Observation & Results-

Results and inference will be drawn on the basis of readings obtained before and after
treatment by using statistical methods.

8.9 Conclusion-

Final conclusion will be drawn on the basis of statistical analysis with overall assessment.

8.10 Summery-

Summery will be written at the end of dissertation.

9 Reference
- Dr. Anna Moreshwar Kunte & Pandit Krushnashastrinavare Edited By Pandit Hari
Sadashiv Shastri Paradkar Ashtanghridaya Of Vagbhata With Sarvangasundar Of
Arundatta & Ayurvedarasayana Of Hemadri Sutrasthan Adhyay 1 Ayushkamiya
adhyaya Verse 6,7 Chaukhamba Sanskrit Sansthan Varanasi Page No 6,7

- Shri indradev tripathi Hindi translation Gadanigraha Kayachikitsa Khanda

Vatarogadhikar Adhyay 19 Verse 160 Chaukhamba Sanskrit Pratishthan Varanasi
page no-508

- Acharya Bramhanand Tripathi Hindi Commentary Sharangdharsamhita Dipika

Hindivyakhya Visheshvakta Vyasamanvita Madhyam Khanda Chapter 2 Verse
86,87 Chaukhamba Surbharti Prakashan Varanasi 1 st Edition Page no- 146

- Dr. Shuvkumar Mishra, Dr. V. Pandirtav & Dr. Sharada Nair Hindi Commentary
Edited By Vaidya Mahendrapal Sing Aarya Sahastrayogam Purvardha Chapter 1
Kashay Prakaran Verse 500 vandmay Anusandhan Ekak Page No-101

- Acharya Bramhanand Tripathi Hindi Commentary Sharangdharsamhita Dipika

Hindivyakhya Visheshvakta Vyasamanvita Madhyam Khanda Chapter 2 Verse 1,2
Chaukhamba Surbharti Prakashan Varanasi 1st Edition Page No.133

- Dr. Anna Moreshwar Kunte & Pandit Krushnashastrinavare Edited By Pandit Hari
Sadashiv Shastri Paradkar Ashtanghridaya Of Vagbhata With Sarvangasundar Of
Arundatta & Ayurvedarasayana Of Hemadri Sutrasthan Adhyay 13
Doshopakramaniya adhyaya Verse 1-3, Chaukhamba Sanskrit Sansthan Varanasi
Page No 211

- Ayurvedacharya Shri Hariharprasadpanderan & Bhishagratna Shri Bramhashankar

Mishra Shastri Shri Bhavaprakash By Bhavamishra Madhyam Khanda Dvitiya Bhag
Adhyay 28 Vatavyadhiadhikar Verse 17 Choukhamba Sanskrit Series Prakashan
Page No. 250
- Kaviraj Ambikadattashastri & Shri Rajeshwardatta Shastri Edited by Shri
Bramhashankar Mishra Bhaishajyaratnavali of Shrigovindadas Adhyaya 26
Vatavyadhi Chikitsa Verse 69,Choukhamba Prakashan Varanasi Page No. 536

- Pandit Jagannatha Sharma Bajpeyee Chakradatta By Chakrapanidutta Aamavta

Adhikara Verse 8 Shri Laxmi Venkateshwar Prakashan 3 rd Edition Page No. 132

- Dr. Anna Moreshwar Kunte & Pandit Krushnashastrinavare Edited By Pandit Hari
Sadashiv Shastri Paradkar Ashtanghridaya Of Vagbhata With Sarvangasundar Of
Arundatta & Ayurvedarasayana Of Hemadri Sutrasthan Adhyay 13
Doshopakramaniya adhyaya Verse 37-39, Chaukhamba Sanskrit Sansthan
Varanasi Page No 218,219

- Ayurvedacharya Shri Hariharprasadpanderan & Bhishagratna Shri Bramhashankar

Mishra Shastri Shri Bhavaprakash By Bhavamishra Madhyam Khanda Dvitiya Bhag
Adhyay 28 Vatavyadhiadhikar Verse 115 Choukhamba Sanskrit Series Prakashan
Page No. 263

- Kshemraj Shri Krushnadas & Lalashaligramji Rasartnakar By Siddhanityanath

Amavataadhikar Verse 7 Shrivenkateshwar Press Page No. 413

- Pt. Shri Umeshananda Sharma & Pt. Brahma Shankar Shastri Madhava Nidana Of
Shri Madhavakar With Sudhalahari Comments Adhyaya 22 Vatavyadhi Nidan Verse
14 Choukhambaa Sanskrit Prakashan 1943 Page No. 98

- Vaidya Yadavji Trikamji Acharya & Prof.R.H. Singh Charak Samhita of Agnivesa
Elaborated by Charaka & Dridhabala Commentary by Shri Chakrapanidatta
Chikitsasthan Adhyay 28 Vatavyadhi Chikitsa Verse 87-88, Chaukhamba Surbharti
Prakashan Varanasi Page no.620,621

- Vaidya Jadavji Trikamji Acharya & Narayan Ram Acharya Sushruta Samhita Of
Sushruta With Nibandhasangraha Commentary of Shri Dalhanacharya Nidansthan
Adhyay 1 Vatavyadhinidan Verse 23-24 Chaukhamba Surbharati Prakashan
Vranasi Page No. 261

- Ayurvedacharya Shri Hariharprasadpanderan & Bhishagratna Shri Bramhashankar

Mishra Shastri Shri Bhavaprakash By Bhavamishra Madhyam Khanda Dvitiya Bhag
Adhyay 28 Vatavyadhiadhikar Verse 144 Choukhamba Sanskrit Series Prakashan
Page No. 268
1 Annexures Annexure 1 - i) Abbreviations
0 ii)Rugnapatrak (Case Proforma)
iii)Drug preparation method
Annexure 2- Formal written consent form.

i) ABBREVIATIONS-
1) A. û¾- A¹É…¡û¾ûSrÉ
2) aÉ. ÌlÉ- aÉSÌlÉaÉëW
3)û zÉÉ. xÉÇ - zÉÉ…¡ïûkÉU xÉÇÌWûiÉÉ
4) xÉÔ- xÉÔ§ÉxjÉÉlÉ
5) qÉ.ZÉÇ.- qÉkrÉqÉ ZÉÇQû

ii)CASE PROFORMA

Reg. no.- OPD No./IPD No.-

Date-
Patient Name-
Age-
Sex-
Maritial Status-
Address-
Occupation- Working hours-
Type of work-
Chief complaints-
Duration

H/O Past illness-

Medical-
Surgical-
Family history-

Swa kula-
Matru kule-
Pitru kula-
Personal history-

Diet:
Nidra:
Vyasan:
Emotional stress:

General examination-
Pulse- Jivha-
BP- Netra
RR- Nakha-
Agni- Twak-
Koshta- Mala- Mutra

PRAKRUTI PARIKSHAN-
Rup Varna Agni ahar cheshta nidra vani buddhi satava Svabha
a v

Vata

Pitta

kapha

Prakruti vishesh-

EXAMINATION OF INDRIYA-
Dnyanendriya- Karmendriya-
Shrotendriya- Hasta-
Sparshanendriya- Pada-
Chakshunendriya- Guda-
Rasanendriya- Upashta-
Ghranendriya- Vaak-

STROTAS PARIKSHAN-
Pranavahastrotas-
Annavahastrotas-
Udakvahastrotas-
Rasavahastrotas-
Raktavahastrotas-
Mansavahastrotas-
Medovahastrotas-
 Asthivahastrotas-
Majjavahastrotas-
Shukravahastrotas-
Aartavavahastrotas-
Purishvahastrotas-
Mutravahastrotas-
Swedavahastrotas-

Examination-
G.C-
Temp-
Pulse-
B.P.-
R.S.-
CVS-

Nidan panchak-

Hetu-
Purvarupa-
Lakshana-
Upashaya-
Samprapti-
Strotas-
Adhisthan-
Vyadhivastha-

Parametric assessment

Sr. no Symptom/ Day 0 Day 15 Day 30 Day 45 Day 60

Sign
1 Katishoola
2 Katigraha
3 SLR
4 Walking
Time
5 Tenderness

Schedule of treatment-
Group-
Administration of drug-
Duration 60 days starting- / / end- / /
iii)Drug preparation method

MüÉRûÉ oÉlÉuÉhrÉÉcÉÏ mÉkSiÉ

1) LMüÉ mÉÉiÉåsrÉÉiÉ ÌSsÉåsÉå AÉæwÉkÉ 20 aÉëäqÉ bÉåFlÉ irÉÉqÉkrÉå 320 ÍqÉ.ÍsÉ. mÉÉhÉÏ bÉÉsÉÉuÉå.

2) lÉÇiÉU iÉå mÉÉiÉåsÉå aÉäxÉ qÉÇS AÉcÉåuÉU PåûFlÉ 40 ÍqÉ.ÍsÉ. ÍvÉssÉMü UÉWûÏsÉ iÉÉå mÉrÉïÇiÉ MüÉRûÉ EMüVûÉuÉÉ.

3) lÉÇiÉU iÉÉå MüÉRûÉ aÉÉVûhÉÏlÉå aÉÉVÕûlÉ bÉåFlÉ MüÉåwhÉ AxÉiÉÉlÉÉ mrÉÉuÉÉ.

qÉɧÉÉ - 40 ÍqÉ.ÍsÉ.
Annexure 2-

CONSENT FORM
CERTIFICATE BY INVESTIGATOR

I certify that I have disclosed all details about the study in the terms easily understood by
the patient.
Date-
Signature Of The Subject

Consent by subject
Name-
Age-
I, exercising me free power of choice, hereby give my consent to be
included as a subject in the clinical validation of Rasnasaptak kwath &Vishwadi kwath in
Katigraha.
The attending physician the purpose of the clinical trial & the nature of drug treatment
&following have informed me to my satisfaction, including the investigations to be
performed to monitor &safeguard my body functions.
I am also aware of my right to opt out of the trial at any time during the course of
the train without having to give the reasons for doing so. I am willing to undergo any risk
for inclusion in this study.

Date:
Signature/thumb impression
Date: Name of the witness
Signature/thumb impression
Relationship
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