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HYPERTENSIVE CARDIOVASCULAR DISEASE, CORONARY ARTERY DISEASE, DIFFUSE ISCHEMIA

CARDIOVASCULAR SYSTEM Risk Factors:


-diet (high in salt and fat)
-smoking
fat and cholesterol intake -sedentary lifestyle
-(+)family history of hypertension
-stress
bad cholesterol: LDL & VLDL
-others: kidney problems & pregnancy

Transports fats from


liver to blood vessels
-stress
-smoke
-drugs Fatty deposit in blood vessels

vasoconstriction Narrowing of blood vessels

Coronary Artery Disease atherosclerosis

Blood supply to the heart

ischemia Oxygen demand Anaerobic respiration

Cardiac contractility Lactic acid


production
ATP
Cardiac output
Chest pain
Arterial blood pressure
(90 mmHg )
DOB

baroreceptors
Sympathetic Nervous System
stimulation

vasoconstriction

afterload

Heart rate
(160 bpm)

Diastolic filling

Cardiac perfusion

Myocardial ischemia

Cardiac output

Hypoperfusion of organs

kidneys brain extremities

dizziness Cold clammy skin


oliguria

Weak pulse
anuria Confusion, altered level of
consciousness, headache
cyanosis
Kidney damage

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