BIONOTE Rapid Test

NEW
Canine Babesia Ab
10㎕

Whole blood
Canine Plasma/Serum 15 min.

Canine Babesia Ab test Detection of Babesia gibsoni

or
C.Babesia Ab

C.Babesia Ab

Whole blood Plasma/Serum 15 min.

■ Ordering Information
Cat. No. Description Type Packing size
RB2126DD Canine Babesia Ab Device 1 Test X 10/Kit
General Information
Purpose: Detection of Canine Babesia gibsoni antibody Product Evaluation
Specimen: Canine whole blood, serum or plasma
PCR
Materials Provided: Positive Negative Sum
·Rapid Canine Babesia Ab test devices Positive 21 7 28
·Anticoagulant tubes Rapid Test Negative 1 71 72
·Disposable capillary tubes Sum 22 78
·Assay diluents bottle
·Sensitivity: 95.4%
Special Features: ·Specificity: 91.0%
·One-step testing procedure: Quick & Accurate ·PCR positive samples from Jeju island (South Korea)
·High sensitivity and specificity and Taiwan

Result Interpretation

Antibody Levels
Parasitemia

0 1 2 3 4 20 52 156
Week 0~1 Week 1~2 Week 2~3 Week 3~16 Week 17~50 Week 51~
Incubation Acute clinical Clinical signs Clinical signs Clinical signs Clinical signs
period signs PCR(+) PCR(+) PCR(-) PCR(-)
PCR(-) PCR(-) Ab(-) Ab(+) Ab(+) Ab(-)
Ab(-) Ab(-)

Clinical Signs PCR Bionote Canine Interpretation Diagnosis

Babesia Ab
+ + + 4~16 weeks after infection Infection
+ + - 2~4 weeks after infection Infection
+ - + At least 17 weeks after infection Recheck necessary
+ - - Only 1~3 weeks passed after infection Recheck necessary

Treatment of Canine Babesia

Small and large Babesia should be differentiated at diagnosis for they require different treatment protocols

Large Babesia spp (Babesia vogeli, canis) - Imidocarb diproprionate

Small Babesia spp. (Babesia gibsoni) - Atovaquone, Azithromycin

http://www.capcvet.org/capc-recommendations/canine-babesiosis1/

Other Diagnostic Method

Intraerythrocytic piroplasms, Hemolytic anemia, thrombocytopenia, splenomegaly, hemoglobinuria, bilirubinemia.
Examination of intraerythrocyte merozoites is known as gold standard for diagnosis of the canine Babesi. However, parasi-
taemia can only be observed from 2~41 days p.i., making diagnosis of the low-level or intermittent parasitaemia difficult.
Therefore we recommend you the serologic diagnosis by using Bionote Rapid Canine Babesia Ab Test Kits. B. vogeli in
dogs, antibody production started on seven days p.i., and then the antibody titres decreased slightly until day 160. (Brandao
et al. 2003)