Name of Patient Baby Vellita Age 20 y.

o Height 5’2
Diagnosis G1P1 PU 31 wks. AOG/LMP cephalic, IPTL, severe Sex Female Weight 60 kg
preeclampsia with pulmonary congestion
Doctor Date of Admission April 28, 2015 Body endomorph
Dr. Karen Kris Balbosa, MD Build
CLASSIFICATIO MECHANISM OF ADVERSE
DRUG DATA INDICATIONS CONTRAINDICATION NURSING RESPONSIBILITIES
N ACTION EFFECTS
Generic name: Pharmacologic: Mechanism of action General: Contraindicated with CNS: sedation, Before:
Methyldopa Sympatholytic not conclusively > hypertension hypersensitivity to headache, > check doctor’s order
(centrally acting) demonsrated; > IV methyldopa, active asthenia, > assess sensitivity to methyldopa,
probably due to drug’s methyldopate: hepatic disease, weakness hepatic disease, renal failure, dialysis
Trade name/s: metabolism, which acute previous methyldopa > assess weight, skin color, lesions,
Methyldopa lowers arterial BP by hypertensive therapy associated with CV: bardycardia, mucous membrane color, lesions,
stimulating the alpha2- crisis; not drug of liver disorders. myocarditis orientation, affect
adrenergic receptors, choice because > educate client about the drug, its
Patient’s dose: Therapeutic: which in turn slow onset of Dermatologic: rash purpose and importance
250mg 1tab TID Antihypertensive decreases action seen as eczema or
sympathetic outflow > unlabeled use: Precaution: lichenoid eruption,
from the CNS hypertension of Use cautiously with toxic epidermal During:
Maximum dose: pregnancy previous liver disease, necrolysis fever > check the label twice
500mg/day in renal failure, dialysis, > administer at the right dose and in
divided doses bilateral cerebrovascular Endocrine: breast the right time
Pregnancy Category disease; pregnancy, enlargement, > do not crush nor chew tablets,
Risk: B lactation gynceomastia, swallow whole
Minimum dose: lactation > discontinue drug if fever,
250mg Onset: varies Patient’s actual abnormalities in liver function tests, or
indication: Interactions: GI: nausea, jaundice occurs
Peak: 2-4 hr Methyldopa is > drug-drug: potentiation vomiting, > discontinue drug if Coombs’-
given to patient to of the pressor effects of distention, positive hemolytic anemia occurs
Availability: Duration: 12-24 hr treat pregnancy- sympathomimetic constipation,
Tablets – 250, incduced amines; increased hepatic necrosis
500mg; Injection Metabolism: hepatic; hypertension hypotension with After:
– 50mg/ml 1-8 hr levodopa, risk of Hematologic: > monitor blood counts periodically to
hypotension during positive Coomb’s detect haemolytic anemia
Distribution: crosses surgery with central test, hemolytic > monitor hepatic function, especially
placenta, enters anesthetics anemia, bone in the first 6-8 wk of therapy or if
breast milk > drug-lab test: marrow unexplained fever appears
Route: methyldopa may depression > ensure that methyldopa is not
PO Excretion: urine interfere with tests for reinstated in such patients
urinary uric acid, serum Other: nasal > report unexplained, prolonged
creatinine, AST, urinary stuffiness, mild general tiredness; yellowing of the
catecholamines arthralgia, myalgia, skin or eyes; fever; bruising; rash.
septic shock-like > document and record.
symptoms

Source: 2011 Source: 2011 Source: 2011 Source: 2011 Source: 2011 Source: 2011 Source: 2011 Lippincott’s Nursing
Lippincott’s NDG Lippincott’s NDG Lippincott’s NDG Lippincott’s NDG Lippincott’s NDG Lippincott’s NDG Drug Guide