DRUG STUDY

Name of Student Nurse: Carissa Mae T. Estrada Date:

Level/Block/Group: 2BSN-04 Hospital/Area:
Clinical Instructor: Ma’am/Mrs. Apolonia Dela Cruz

MAGNESIUM SULFATE

NAME OF DRUG MECHANISM CONTRAIND SIDE EFFECTS ADVERSE NURSING

OF ACTION ICATIONS EFFECTS RESPONSIBILITIES
GENERIC NAME Magnesium is Hypersensiti -heart CNS: -Magnesium levels
the second vity disturbances drowsiness, must be monitored
- Magnesium most plentiful -breathing depressed frequently by
sulfate cation of the Myocardial difficulties reflexes, flaccid checking serum
intracellular damage, -poor reflexes paralysis. levels every 6 to 8
BRAND NAME fluids. It is -confusion hours or clinically by
essential for Diabetic -weakness CV: checking patellar
- Epsom Salt the activity of coma, -flushing (warmth, hypotension, reflexes or urinary
- Sulfamag many enzyme redness, or tingly flushing, output.
systems and Heart block feeling) circulatory
CLASSIFICATION plays an -sweating collapse, - Inject I.V. bolus
important role Hypermagn -lowered blood depressed slowly to avoid
Pharmacologic with regard to esemia pressure cardiac function. respiratory or cardiac
classification: mineral/ neurochemica -feeling like you arrest.
electrolyte l transmission Hypercalce might pass out Metabolic:
and muscular mia -anxiety hypocalcemia. -Administer by
Therapeutic excitability. -cold feeling constant infusion
classification: Magnesium Administrati -extreme Respiratory: pump if possible;
anticonvulsant sulfate on during 2 drowsiness respiratory maximum infusion
reduces hours -muscle tightness paralysis rate is 150
Pregnancy risk category striated preceding or contraction, or mg/minute. Rapid
A muscle delivery for headache. Skin: drip causes feeling of
INDICATION contractions mothers diaphoresis heat.
-Prevention of seizures and blocks with
in peripheral toxemia of Other: - Test knee jerk reflex
eclampsia/preeclampsia neuromuscula pregnancy hypothermia. before each dose; if
r transmission absent, discontinue
-Constipation by reducing magnesium. Use of
acetylcholine drug beyond this
-Hypomagnesemia release at the point risks
myoneural respiratory center
-Acute nephritis junction. failure.
(pediatric patients) Additionally,
Magnesium - Monitor patient for
-Cardiac arrhythmias inhibits Ca2+ magnesium toxicity
secondary to influx through and monitor I.V.
hypomagnesemia
 dihydropyridin infusion to avoid
-Soaking minor cuts or e-sensitive, circulatory overload.
bruises voltage-
DOSAGE & FREQUENCY dependent -After use in toxemic
channels. This women within 24
Preeclampsia,
accounts for hours before
Eclampsia
much of its delivery, newborn
Adult: IM/IV 4 g in 250
relaxant requires observation
mL D5W infused slowly,
action on for signs of
followed by 4–5 g IM in
vascular magnesium toxicity,
alternate buttocks q4h
smooth including
muscle. neuromuscular and
-Hypomagnesemia
respiratory
Seizures
- depression.
Adult: IM/IV Mild, 1 g
q6h for 4 doses; Severe,
-Observe newborns
250 mg/kg infused over
of mothers who
4h
received parenteral
Child: IV 20–100 mg/kg
magnesium sulfate
q4–6h prn
within a few hours of
delivery for signs of
-Laxative
toxicity, including
Adult: PO 10–15 g
respiratory and
once/d
neuromuscular
depression.
-Total Parenteral
Nutrition
-Recommended daily
Adult: IV 0.5–3 g/d
allowances of
magnesium are
obtained in a normal
-Arrhythmias.
diet. Rich sources are
Adult: give 1 to 6 g I.V.
whole-grain cereals,
over several minutes
legumes, nuts,
followed by 3- to 20-
meats, seafood, milk,
mg/minute I.V. infusion
most green leafy
for 5 to 48 hours
vegetables, and
bananas.