EEE1008 BIO-MEDICAL INSTRUMENTATION L T P J C

3 0 0 4 4
Pre-requisite NIL Syllabus version
Anti-requisite v. 2.0
Course Objectives:
1. To give an understanding of the biological signals and signal acquisition
2. To provide the design concepts of bioelectric amplifiers
3. To learn the principle and operation of various biomedical systems

Expected Course Outcomes:

On the completion of this course the student will be able to:
1. Evaluate and analyse the different physiological signals
2. Relate the knowledge to select appropriate medical instruments
3. Design and maintain the bio electric devices used for diagnostic equipment
4. Develop and analyse the therapeutic devices.
5. Create and understand the procedure in analysis of Blood used in medical laboratory
6. Evaluate the process involved in blood cell counters and sensors
7. Use the knowledge to differentiate the advanced diagnostic techniques.
8. Design a component or a product applying all the relevant standards with realistic
constraints

Student Learning Outcomes (SLO): 5,9,10

5. Having design thinking capability
9. Having problem solving ability- solving social issues and engineering problems
10. Having a clear understanding of professional and ethical responsibility
Module:1 Introduction to Biomedical Instrumentation and Measurement 8 Hours
Sources of bioelectric potentials, cardiovascular system, Central nervous system, Muscular System,
linear/nonlinear analysis of different physiological signals (ECG, EEG, EMG), Electrode theory-
mathematical analysis including Nernst equation, Goldman equation, Electrical conductivity of
electrode, Electrodes for ECG, EEG &EMG.

Module:2 General Considerations of Medical Instruments 8 Hours

Operational Amplifiers, Bioelectric Amplifiers, Selection of biomedical amplifiers – Isolation
amplifiers, Charge amplifiers and Chopper amplifier. Characteristics of biomedical recorder
amplifiers, Physiological effects of electric currents, Electric shock hazards and leakage currents,
Methods of accident prevention.

Module:3 Diagnostic Equipment 7 Hour

ECG Lead Configuration, Vector cardiograph, Phono-cardiograph, EEG and EMG Electrode system,
Recorders, Measurement of various volumes/capacity of lungs, Spirometer. Measurement of cardiac
output, blood flow and blood pressure.

Module:4 Therapeutic Equipment 6 Hours

Cardiac pacemakers, cardiac defibrillators, nerve & muscle stimulators, diathermy-types, ventilators,
Dialyzer.

Module:5 Medical Laboratory Instrumentation 5 Hours

Analysis of Blood-Measurement of pH, pO2 and pCO2 value of blood using pH/gas analyzers
Module:6 Medical Laboratory Measurement 4 Hours
Photometers, Hematology, Blood cell counters, Electrophoresis- Serum detection and classification,
Blood Glucose Sensors, GSR measurements.

Module:7 Advanced Diagnostic Techniques 5 Hours

2D, 3D Analysis and Visualization (X-Ray, MRI, CT), Biomedical Spectroscopy, Optical coherence
tomography, Fluorescence based Bio-detection & Bio-imaging- Case study: Telemedicine based
health care monitoring system.

Module:8 Contemporary issues: 2 hours

Text Book(s)
Leslie Cromwell, Fred J, Weibell & Erich A and P Feiffer, ‘Biomedical Instrumentation and
1.
Measurements’, 2nd Edition, PHI, 2011.
J.J. Carr & J.M. Brown, ‘Introduction to biomedical Equipment Technology’, Prentice Hall,
2.
4th Edition, 2011.
Reference Books
R. S. Khandpur, ‘Handbook of Biomedical Instrumentation’, Tata Mc-Graw Hill, 2nd
1.
edition, 2014.
John.E. Hall, Guyton and Hall, Textbook of Medical Physiology, Saunders; 13th Edition,
2.
2015.
Rangaraj M. Rangayyan, ‘Biomedical Signal Analysis’, A Case-Study Approach, Wiley, 2nd
3.
Edition, 2015.
Mode of Evaluation: CAT I & II – 30%, DA I & II – 20%, Quiz – 10%, FAT – 40%
Mode of assessment:
Recommended by Board of Studies 30/11/2015
Approved by Academic Council 39th AC Date 17/12/2015