The document discusses the benefits of exercise for mental health. Regular physical activity can help reduce anxiety and depression and improve mood and cognitive functioning. Exercise causes chemical changes in the brain that may help alleviate symptoms of mental illness and also provides a time of distraction from daily stressors.
The document discusses the benefits of exercise for mental health. Regular physical activity can help reduce anxiety and depression and improve mood and cognitive functioning. Exercise causes chemical changes in the brain that may help alleviate symptoms of mental illness and also provides a time of distraction from daily stressors.
The document discusses the benefits of exercise for mental health. Regular physical activity can help reduce anxiety and depression and improve mood and cognitive functioning. Exercise causes chemical changes in the brain that may help alleviate symptoms of mental illness and also provides a time of distraction from daily stressors.
Homo sapiens eukaryotic translation initiation factor 3, subunit M (EIF3M), mRNA
NCBI Reference Sequence: NM_006360.4 FASTA Graphics Go to:
LOCUS NM_006360 1338 bp mRNA linear PRI 16-MAR-2014
DEFINITION Homo sapiens eukaryotic translation initiation factor 3, subunit M (EIF3M), mRNA. ACCESSION NM_006360 VERSION NM_006360.4 GI:365777428 KEYWORDS RefSeq. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. REFERENCE 1 (bases 1 to 1338) AUTHORS Proshkin SA, Shematorova EK, Souslova EA, Proshkina GM and Shpakovski GV. TITLE A minor isoform of the human RNA polymerase II subunit hRPB11 (POLR2J) interacts with several components of the translation initiation factor eIF3 JOURNAL Biochemistry Mosc. 76 (8), 976-980 (2011) PUBMED 22022972 REMARK GeneRIF: POLR2J interacts with three different subunits of eIF3, eIF3a, eIF3i, and eIF3m. REFERENCE 2 (bases 1 to 1338) AUTHORS Goh SH, Hong SH, Hong SH, Lee BC, Ju MH, Jeong JS, Cho YR, Kim IH and Lee YS. TITLE eIF3m expression influences the regulation of tumorigenesis-related genes in human colon cancer JOURNAL Oncogene 30 (4), 398-409 (2011) PUBMED 20838379 REMARK GeneRIF: eIF3m mediates regulation of tumorigenesis-related genes in human colon cancer REFERENCE 3 (bases 1 to 1338) AUTHORS Cheshenko N, Trepanier JB, Segarra TJ, Fuller AO and Herold BC. TITLE HSV usurps eukaryotic initiation factor 3 subunit M for viral protein translation: novel prevention target JOURNAL PLoS ONE 5 (7), E11829 (2010) PUBMED 20676407 REMARK GeneRIF: Results demonstrate that B5 plays a major role in the initiation of HSV protein translation and could provide a novel target for strategies to prevent primary and recurrent herpetic disease. Publication Status: Online-Only REFERENCE 4 (bases 1 to 1338) AUTHORS Chew SK, Chen P, Link N, Galindo KA, Pogue K and Abrams JM. TITLE Genome-wide silencing in Drosophila captures conserved apoptotic effectors JOURNAL Nature 460 (7251), 123-127 (2009) PUBMED 19483676 REMARK GeneRIF: the human Tango7 counterpart, PCID1 (also known as EIF3M), impinged on caspase 9, revealing a new regulatory axis affecting the apoptosome REFERENCE 5 (bases 1 to 1338) AUTHORS Zhou M, Sandercock AM, Fraser CS, Ridlova G, Stephens E, Schenauer MR, Yokoi-Fong T, Barsky D, Leary JA, Hershey JW, Doudna JA and Robinson CV. TITLE Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3 JOURNAL Proc. Natl. Acad. Sci. U.S.A. 105 (47), 18139-18144 (2008) PUBMED 18599441 REFERENCE 6 (bases 1 to 1338) AUTHORS Kobayashi K, Xin Y, Ymer SI, Werther GA and Russo VC. TITLE Subtractive hybridisation screen identifies genes regulated by glucose deprivation in human neuroblastoma cells JOURNAL Brain Res. 1170, 129-139 (2007) PUBMED 17719568 REFERENCE 7 (bases 1 to 1338) AUTHORS Damoc E, Fraser CS, Zhou M, Videler H, Mayeur GL, Hershey JW, Doudna JA, Robinson CV and Leary JA. TITLE Structural characterization of the human eukaryotic initiation factor 3 protein complex by mass spectrometry JOURNAL Mol. Cell Proteomics 6 (7), 1135-1146 (2007) PUBMED 17322308 REFERENCE 8 (bases 1 to 1338) AUTHORS Perez-Romero P and Fuller AO. TITLE The C terminus of the B5 receptor for herpes simplex virus contains a functional region important for infection JOURNAL J. Virol. 79 (12), 7431-7437 (2005) PUBMED 15919899 REMARK GeneRIF: Concluded that the C terminus of B5 contains a functional region that is important for the B5 receptor to mediate events in HSV entry. REFERENCE 9 (bases 1 to 1338) AUTHORS Perez A, Li QX, Perez-Romero P, Delassus G, Lopez SR, Sutter S, McLaren N and Fuller AO. TITLE A new class of receptor for herpes simplex virus has heptad repeat motifs that are common to membrane fusion proteins JOURNAL J. Virol. 79 (12), 7419-7430 (2005) PUBMED 15919898 REMARK GeneRIF: Cloned a previously uncharacterized human gene, designated hfl-B5, and showed that it encodes a type II cell surface membrane protein that can serve as a receptor for entry of HSV. REFERENCE 10 (bases 1 to 1338) AUTHORS Lehner B and Sanderson CM. TITLE A protein interaction framework for human mRNA degradation JOURNAL Genome Res. 14 (7), 1315-1323 (2004) PUBMED 15231747 COMMENT VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DB479224.1, BC019103.2 and AL078477.5. On Dec 24, 2011 this sequence version replaced gi:52851442.
Summary: This gene encodes a protein that is part of the