Drug Study Format
Name: Sheryl Ann B. Pedines BSN-III
Generic Name: Lorazepam
Brand Name: Ativan
Dose/ Route/Frequency: 5mg IV
Mechanism of Action: Depresses the CNS,
probably by potentiating GABA, an inhibitor
neurotransmitter.
Physiologic classification: Anxiolytic
Pharmacologic Classification: Benzodiazepine
Desired Effect: to produce calming effect.
Indication/s: Preoperative sedation
Contraindication/s: Hypersensitivity to drug, Acute
angle-closure glaucoma, Coma or CNS depression, and
Hepatic or renal failure.
Side Effects:
Adverse Effects:
SEIZURE Date:
Nursing Responsibilities
Action Rationale
1. Verify doctor’s order. To ensure that this the drug of choice for the patient.
2. Consider the rights of drug administration To prevent medical error and to ensure safety.
3. Explain the purpose of the drug to the family To promote understanding and compliance.
of patient.
5. Ensure the patients receives full course of To increase effectiveness and decrease the risk for
lorazepam as prescribed. developing resistant of the disease.
6. During I.V administration, monitor ECG and To prevent life-threatening.
cardiovascular and respiratory status.
8. Monitor vital signs closely. To provide critical information needed to make life-
saving decisions
9. Watch closely for CNS depression. To prevent life-threatening.
10. Monitor for signs and symptoms, such as To prevent another complication.
hypotension, coma, confusion, and labored
breathing.
12. As appropriate, review all other To ensure safety.
significant and life-threatening adverse
reactions and interactions.
10.Monitor patient compliance of the drug To determine the effectiveness of the drug.
therapy.
Headache, dizziness, drowsiness, blurred vision, nausea, abdominal discomfort, increased or decreased
appetite, lethargy, disorientation
Apnea, cardiac arrest, cardiovascular collapse, tachycardia, bradycardia, diplopia, hypotension,
amnesia, agitation, ataxia, depression, asthenia
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