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Unwanted Hair

and Hirsutism
Unwanted Hair and Hirsutism

What is hirsutism? 4
Why should you treat unwanted hair? 5
What is ‘normal’ hair growth? 5
What can cause hirsutism? 6
What tests might be done? 8
How does the patient feel about her hair growth? 9
What treatments are available? 10
Facial and Body hair growth scoring 16
4 5

What is hirsutism? Why should you treat unwanted hair?


Hirsutism means excessive or unwanted hair on the face or body on Unwanted hair growth in women is considered abnormal in our society and
‘androgen dependent areas‘ in women (i.e. in places usually seen in men). this can cause distress or embarrassment and affect a woman psychologically.
Upper lip, chin, chest, abdomen (tummy), or back are common areas for Hypertrichosis (generalised excessive hair) or hirsutism (excessive hair on an-
hirsutism. This is different from hypertrichosis, which is defined as an excess drogen dependent areas in women) are rarely caused by a serious illness. Ho-
of hair in men or women at any site (even in non-androgen-dependent wever, in some cases, hypertrichosis and hirsutism may be caused by a medical
regions). condition. This can easily be investigated by a doctor. However, quite often
The normal amount of body hair varies widely among women. When coarse women do not realise that there are treatments available to reduce hair
hairs grow where women typically do not grow coarse hair, such as the upper growth or to eliminate hair. Therefore they do not even talk to their doctor
lip, chin, chest, abdomen (tummy), or back, the condition is called about it.
hirsutism. Hirsutism is not limited to dark haired people, all hair colours If a patient has trouble controlling body or facial hair by cosmetic methods, or
(blonde, red, grey) may also be coarse and grow in unwanted areas. is upset by the condition, she should discuss this with her doctor. S/he may
What is considered normal for a woman and what is considered hirsutism de- refer the patient to a specialist if s/he thinks that this is necessary. The specia-
pends on factors such as culture and race. Unwanted facial hair is usually the list may be an endocrinologist, dermatologist or gynaecologist, who can pro-
main concern to women. vide reassurance, arrange appropriate tests and discuss possible treatments.

Symptoms associated with excessive hair growth may include: What is ‘normal’ hair growth?
• greasy skin The body is completely covered with hair, except the lips, the palms of
the hands and the soles of the feet. But on most of the body, the hair
• acne
is so fine and soft that you cannot see it easily. Normally, a human
• menstrual cycle changes being has two types of hairs:
• decreased breast size 1. Terminal hairs (coloured and thicker hair on the scalp, but also found on
• masculine signs (such as deepening of the voice) eyebrows, eyelashes, groin, and under the arms)
• increased muscle size 2 Vellus hairs (fine and light, normally not coloured. These hairs can become
• hair loss on the scalp terminal hairs in the presence of male-type hormones)
• change in libido (sex drive) Women have the same number of hair follicles (places where hair is produ-
ced) on their body and face as men do. In women, most of the hair follicles
on the face and the body produce fine and light (vellus type) hair. The male
If a patient has any of these symptoms, or if they think that a medicine they
hormone, testosterone, makes hairs on men grow thicker, darker and longer,
are taking might be making the unwanted hair growth worse, they should
so that they appear more noticeable. All women produce small amounts of
contact a doctor.
testosterone and this allows terminal hairs to appear in the groin and armpit
areas, and around the brown circles of the nipple. This is normal and happens
from around puberty. However, when there are higher levels of male hormo-
nes in women, terminal hairs can develop over the shoulders, over parts of
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2. Ethnic/Racial
Women from some ethnic groups (e.g. from Mediterranean countries) are
more likely to have darker, more dense hair. There is no underlying medical
condition causing the excess hair, and this is termed ‘ethnic hypertrichosis’.

3. Polycystic Ovary Syndrome (PCOS)


This is a common cause of hirsutism and may be associated with other
symptoms such as acne, irregular periods, infertility and obesity. The condition
is usually diagnosed in adulthood, but the symptoms often start in the teen-
age years. Women with hirsutism caused by PCOS don't always have other
symptoms of the condition.

the back, upper legs and abdomen. The amount of terminal hair increases
4. Medication
with age in women, and some races naturally grow longer and darker hair
(even on the body) although they do not produce any extra hormones. Some drugs are able to induce hair growth in general, and some drugs can
contribute to hirsutism, e.g.

What can cause hirsutism?


• Glucocorticoids
If the unwanted hair growth is mild and the patient’s periods are regular, it is
unlikely that there is a serious medical problem. If the hirsutism is severe, • Cyclosporin (immunosuppressor used in organ transplant patients,
and/or the patient has irregular periods, or any other symptoms (e.g. baldness in psoriasis, atopic dermatitis and in arthritis)
or deepening of the voice), there may be a medical reason for the hirsutism. • Progestative implants, intra uterine devices (IUDs) with
Hirsutism can be caused by several different factors. The best treatment will progesterone or progestagen
depend upon which factor is causing the unwanted hair growth. • Body building drugs, i.e. ‘anabolic steroids’
• Phenytoin (or epanutin - used in epilepsy)
Reasons for hirsutism include: • Phenothiazines
1. Inherited/familial
In most women, hirsutism is inherited and may be present in other female 5. Over-production of male-type hormones
relatives. These women tend to have normal amounts of testosterone, but
All women produce small amounts of male-type hormones such as testoste-
their hair follicles are more sensitive to testosterone and so grow more quickly
rone in the adrenal glands, the ovary and in fat and muscle tissue. Hirsutism
and thicker. The increased hair growth is usually noticed in the late teenage
can develop if one or more of these sites increase their production. Blood
years, and tends to gradually get more severe as the woman gets older.
tests and abdominal scans can help to find out where and why the hormones
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are being over-produced. Obesity can cause changes in how the hormones The levels of male and female hormones in the blood may be tested.
are regulated, and so lead to hirsutism. Increased weight may increase the Occasionally, other hormone tests are needed and these may be done by an
amount of the male hormone produced by the body and so in addition endocrinologist or gynaecologist. Sometimes, a scan of the ovaries or other
weight loss may enhance the result of any treatment. glands may be helpful.

6. Congenital Adrenal Hyperplasia How does the patient feel about her hair growth?
In rare cases, hirsutism may be caused by an increase in hormone production Some people find it easy to discuss their worries with their doctor. For others,
by the adrenal glands. This condition is called Congenital Adrenal Hyperplasia this can be more difficult; especially with an embarrassing or upsetting
and is hereditary. Often it is not diagnosed until teenage years or later. The condition such as hirsutism. A patient may find the answers to the following
condition is usually treated with small amounts of steroids. questions useful, to help her explain how she feels to her doctor.

7. Benign and malignant tumors


1. Does your unwanted hair growth interfere with your daily life?
In very rare cases androgen producing tumors of the ovaries or the adrenal
2. Do you check your hair growth in the mirror more often
gland can lead to a sudden onset of excessive hair growth, and other signs
than before?
of virilisation. Although it is very rare it is important to detect as
3. In the last few weeks, have you felt that other people are looking
early as possible this cause. at your excessive hair growth more often?
4. Does your unwanted hair growth sometimes make you feel
8. Others sad or are you worried about it?
E.g. hyperprolactinaemia, Cushing’s disease, acromegaly (which are quite rare). 5. Are you very keen to reduce your unwanted hair growth?

What tests might be done? If the patient answered ‘yes’ to at least three of these questions, she worries.
A physical examination will probably carried out and also following questions It is also common for women to remove their unwanted hair before they visit
should be answered. their doctor, or go outside the house (especially if the unwanted hair is on the
face). This can make it difficult for the doctor to assess how severe the hair
• Do other members of your family also have excessive
growth is. In this case, it might be useful for the patient to use the scoring
amounts of hair?
scale at page 16 to show her doctor, or to document treatment changes
• What medications are you taking?
where the unwanted hair is, giving an idea of how severe the growth is.
• Have your periods been regular?
• Are you pregnant?
• Have you noticed other signs of excess male hormones such
as increased muscle mass, deepening voice, acne, or
decreased breast size?
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What treatments are available?


Women with hirsutism should be tested for a medical cause, and should then
be treated. If there is no underlying cause, hair management is the only way
forward. Treatment of hirsutism depends on the cause of the problem. If it is
a racial, ethnic, or family trait, no medical treatment may be necessary or
prescribed. Instead, a patient may choose to see a beautician for removal of
unwanted hair or be advised on home methods for removing unwanted hair.
Weight loss is an important treatment for hirsutism. In overweight women,
weight loss can decrease male hormone levels and reduce hair growth.

1. Cosmetic Treatment
• Bleaching is an option for dark hair and makes the excessive hair less ob-
vious. Bleaching works well on the arms, thighs, and just below the nose. • Electrolysis may cause permanent hair loss, but takes time as a small area
The results are immediate, but bleaching needs to be done frequently, de- is treated every few weeks, and unskilled treatment may cause scarring.
pending on how quickly the hair grows. Bleaching may also leave skin red, Electrolysis uses electrical current to damage individual hair follicles so they
cause rash/skin irritation, can be painful, is time-consuming, and can make do not grow back. This is expensive and requires multiple treatments.
hair more obvious • Tweezing is good for removing a few hairs, such as around the eyebrows.
• Depilatory creams dissolve the hair, and the results are immediate, but The results are immediate, but tweezing needs to be done frequently.
the treatment needs to be done frequently, which can be uncomfortable. Tweezing may also leave skin red, cause rash/skin irritation, can be painful,
Depilatory creams may also cause irritation to the skin. and is time-consuming.

• Shaving: electric shavers are probably better than the wet type, as there is
less tendency to irritate or damage the skin. The results are immediate, but 2. Medical Treatment
shaving needs to be done frequently, and can also cause a rash/skin irrita- In most cases, hirsutism will return once the medical treatment is stopped.
tion, and is time-consuming. Shaving can also leave stubble, and although
shaving does not influence the hair thickness the newly grown hair appe-
Examples of drugs* that may be prescribed are:
ars thicker.
• Eflornithine cream: a prescription cream applied twice per day to slow
• Waxing pulls hairs out from the roots. The results are immediate, but wa-
the growth of unwanted facial hair. First effects can usually be seen after
xing needs to be done frequently and the hair must be allowed to grow
8 weeks of treatment. Therefore, in the beginning it should ideally be
long enough to be able to repeat the procedure. Waxing may also leave
combined with another form of therapy such as laser, waxing etc.
skin red, cause rash/skin irritation, can lead to pimples full of pus, can be
painful, and is time-consuming.
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• Ethinyl estradiol/cyproterone acetate or 3. Photoepilation Therapy


ethinyl estradiol/drospirenone. These combinations contain oestrogen Photoepilation therapy is the most efficient method for coloured (dark) hair.
(a female hormone) and a low dose of other hormones which have an Significant improvement is usually achieved after at least 5 – 7 sessions
anti-male hormone action – see below. These hormones may not suit (depending on the laser or light source type, colour of hair etc.), and the
everyone, especially women over the age of 40 years. Side effects include benefits are long term. However, the treatment is expensive, it can cause
bleeding between periods, tender breasts, nausea (feeling sick) and burning and/or stinging sensation, can be painful, and sessions should only be
headaches, especially in the first few months. The hormones should not performed every 4 – 8 weeks to enable the hair follicle to enter a new growth
be given to women who are overweight, smoke, or have a job or lifestyle phase. Laser treatment damages individual hair follicles so they do not grow
that means they sit down a lot. This is because the medicine can increase back. Lasers may not work well on blonde, red or grey hair. Several treatments
the risk of a blood clot in people with these factors. are often required, but regrowth can be slowed by using lasers in combination
• Cyproterone acetate or drospirenone (anti-androgens). Anti-androgens with eflornithine cream.
work against male hormones. Women should not become pregnant
during and for up to 3 months following treatment with anti-androgens as
Complications can result from any topical treatment or hair removal
they can interfere with a baby’s development. Cyproterone acetate is also
procedure. It is important to follow all directions for any hair removal
available in doses that are larger and more effective than the dose found
product and to be aware of the risks involved with any professional
in the combination product. The main disadvantage is that higher doses
hair removal procedure.
are more likely to produce side effects including weight gain, depression,
and loss of libido (sex drive). Higher doses should therefore only be given
to women with moderate or severe hirsutism and always with a safe
4. Psychological Management
contraceptive method, in women of childbearing age.
If a patient’s unwanted hair growth is troubling her, affecting her daily life,
• Spironolactone is a weak diuretic (water tablet) that has some anti-an-
causing her anxiety, or making her depressed, she should talk to her doctor.
drogen activity. Like cyproterone, safe contraception should be practised
Her doctor will be able to advise about available psychotherapy treatment.
to avoid pregnancy. Side effects include tender breasts and irregular
periods. Facial and Body hair growth scoring – The Ferriman-Gallwey Score
• Metformin. This drug is normally used in the treatment of diabetes. In
recent years it has been shown to be beneficial to women with PCOS (see This scale can be used to decide how severe hirsutism is. Each area is given a
above). The main side effects of metformin are nausea, abdominal cramps, number from 1 to 4. If there is only a little extra hair growth, the area is given
flatulence (wind), diarrhoea and constipation. a score of 1, rising to a score of 4 for areas with a lot of excess hair growth.
* NB - some drugs may not be available in all countries A patient can discuss how to use this scale with her doctor; she could use it
to show him/her where she feels her excess hair growth is, and how severe it
is. Also, the scale can be used to monitor the success of treatment, by scoring
at regular intervals. A doctor will advise how to use the scale in the best way
for each patient.
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Notes Facial and body hair growth scoring 15

Name:

Date of birth:

Assess for Hirsutism as follows:

Dates 0 1 2 3 4

1st visit

2nd visit

3rd visit
A few hairs at Small mousta- Moustache Moustache
outer margin che at outer extending halfway extending to
margin from outer margin mid-line

1st visit

2nd visit

3rd visit
A few Scattered hairs Complete cover, light and heavy
scattered hairs with small
concentrations

1st visit

2nd visit

3rd visit
Circumareola With mid-line Fusion of these Complete cover
hairs hair in addition areas, with three-
quarter cover

1st visit

2nd visit

3rd visit
A few scattered Rather more, Complete cover, light and heavy
hairs still scattered

1st visit

2nd visit

3rd visit
A sacral tuft With some lateral Three quarter Complete
of hair extension cover cover

1st visit

2nd visit

3rd visit
E-mail: experts@skinacademy.eu A few mid-line
hairs
Rather more,
still mid-line
Half and full cover

1st visit

2nd visit

3rd visit
A few mid-line Mid-line streak A mid-line band An inverted V
hairs of hair of hair shape grow

Adapted from Ferriman and Gallwey (Ferriman D, Gallwey JD


J Clin Endocrinol Metab. 1961;21:1440-1446)
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E-mail: experts@skinacademy.eu

This document is a consensus of opinion from the Experts of the Skin Academy.
Sponsored by an unrestricted educational grant from Almirall Laboratoires, Spain.
E-mail: experts@skinacademy.eu

Printed by: Almirall Hermal GmbH


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